hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_05832

Confidence: Medium

Genename	Protein Name	Links
DERL2	Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)	UniProt NCBI
SH3PXD2A	SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains)	UniProt NCBI
RTN4	Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5)	UniProt NCBI
ARL6IP1	ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Apoptotic regulator in the membrane of the endoplasmic reticulum)	UniProt NCBI
RTN3	Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII)	UniProt NCBI
RABAC1	Prenylated Rab acceptor protein 1 (PRA1 family protein 1)	UniProt NCBI
FAM210B	Protein FAM210B, mitochondrial	UniProt NCBI
DHCR24	Delta(24)-sterol reductase (EC 1.3.1.72) (24-dehydrocholesterol reductase) (3-beta-hydroxysterol Delta-24-reductase) (Diminuto/dwarf1 homolog) (Seladin-1)	UniProt NCBI
CYB5R3	NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) [Cleaved into: NADH-cytochrome b5 reductase 3 membrane-bound form; NADH-cytochrome b5 reductase 3 soluble form]	UniProt NCBI
RTN2	Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI)	UniProt NCBI
TMEM208	Transmembrane protein 208	UniProt NCBI
SPOPL	Speckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2)	UniProt NCBI
SPOP	Speckle-type POZ protein (HIB homolog 1) (Roadkill homolog 1)	UniProt NCBI
TM9SF1	Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70)	UniProt NCBI
ATL3	Atlastin-3 (EC 3.6.5.-)	UniProt NCBI
ATP1B2	Sodium/potassium-transporting ATPase subunit beta-2 (Adhesion molecule in glia) (AMOG) (Sodium/potassium-dependent ATPase subunit beta-2)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0071786	6.01773964241e-05	0.25	ATL3 ARL6IP1 RTN4 RTN3	endoplasmic reticulum tubular network organization
GO:0071787	0.000203300410527	0.1875	RTN4 ARL6IP1 RTN3	endoplasmic reticulum tubular network formation
GO:0007029	0.00705166336964	0.25	ATL3 ARL6IP1 RTN4 RTN3	endoplasmic reticulum organization

Edges

Protein 1	Protein 2	Score	Precision	Evidence
ARL6IP1	RTN4	0.792	0.758	bioplex (RTN4) bioplex_WMM
ATL3	RTN4	0.378	0.547	hein_WMM bioplex (RTN4) bioplex_WMM hein (ATL3) boldt_WMM treiber_WMM
RTN2	RTN4	0.308	0.503	bioplex (RTN4) bioplex_WMM
RTN4	ATP1B2	0.23	0.468	bioplex (ATP1B2,RTN4) bioplex_WMM
RABAC1	RTN4	0.217	0.464	bioplex (RTN4) bioplex_WMM
CYB5R3	RTN4	0.141	0.405	bioplex (RTN4) bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM
TMEM208	RTN4	0.135	0.406	bioplex (RTN4) bioplex_WMM
DERL2	RTN4	0.124	0.395	bioplex (RTN4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
SPOPL	RTN4	0.112	0.38	bioplex (RTN4) bioplex_WMM
SH3PXD2A	RTN4	0.084	0.348	bioplex () treiber_WMM bioplex_WMM
RTN3	RTN4	0.063	0.348	hein_WMM bioplex (RTN4) bioplex_WMM youn_WMM gupta_WMM boldt_WMM treiber_WMM
SPOP	RTN4	0.062	0.341	bioplex (RTN4) bioplex_WMM youn_WMM treiber_WMM
TM9SF1	RTN4	0.024	0.214	bioplex (RTN4) bioplex_WMM boldt boldt_WMM
DHCR24	RTN4	0.021	0.194	bioplex (DHCR24,RTN4) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM
FAM210B	RTN4	0.02	0.188	bioplex_WMM bioplex ()
RTN2	RTN3	0.011	0.149	bioplex_WMM WMM_only
RTN2	ARL6IP1	0.01	0.1	bioplex_WMM WMM_only
TMEM208	RTN3	0.009	0.11	bioplex_WMM WMM_only
ARL6IP1	RTN3	0.009	0.11	bioplex_WMM WMM_only
RTN2	TMEM208	0.009	0.105	bioplex_WMM WMM_only
TMEM208	ARL6IP1	0.009	0.107	bioplex_WMM WMM_only
RABAC1	TMEM208	0.009	0.09	bioplex_WMM WMM_only
ARL6IP1	ATP1B2	0.009	0.099	bioplex_WMM WMM_only
RABAC1	ATP1B2	0.008	0.095	bioplex_WMM WMM_only
SPOPL	ATP1B2	0.008	0.091	bioplex_WMM WMM_only
RABAC1	ARL6IP1	0.008	0.089	bioplex_WMM WMM_only
ATL3	ARL6IP1	0.008	0.09	bioplex_WMM WMM_only
TM9SF1	DHCR24	0.008	0.087	bioplex_WMM boldt boldt_WMM
RTN2	RABAC1	0.008	0.086	bioplex_WMM WMM_only
TMEM208	SPOPL	0.008	0.085	bioplex_WMM WMM_only
ARL6IP1	SPOPL	0.008	0.085	bioplex_WMM WMM_only
RABAC1	SPOPL	0.008	0.082	bioplex_WMM WMM_only
SPOP	ATP1B2	0.008	0.083	bioplex_WMM WMM_only
FAM210B	DHCR24	0.008	0.069	bioplex_WMM WMM_only
ARL6IP1	SPOP	0.008	0.065	bioplex_WMM WMM_only
TMEM208	ATP1B2	0.008	0.06	bioplex_WMM WMM_only
SPOPL	SPOP	0.008	0.06	bioplex_WMM WMM_only
RABAC1	SPOP	0.008	0.059	bioplex_WMM WMM_only
TM9SF1	DERL2	0.008	0.05	bioplex_WMM boldt boldt_WMM
RABAC1	FAM210B	0.008	0.04	bioplex_WMM WMM_only
RABAC1	RTN3	0.008	0.044	bioplex_WMM WMM_only
ATL3	ATP1B2	0.008	0.041	bioplex_WMM WMM_only
RTN2	ATP1B2	0.008	0.032	bioplex_WMM WMM_only
TM9SF1	ARL6IP1	0.008	0.032	bioplex_WMM WMM_only
CYB5R3	FAM210B	0.008	0.031	bioplex_WMM WMM_only
ATL3	TMEM208	0.008	0.031	bioplex_WMM WMM_only
SPOPL	RTN3	0.008	0.038	bioplex_WMM WMM_only
RTN2	SPOPL	0.008	0.037	bioplex_WMM WMM_only
ATL3	SPOPL	0.008	0.025	bioplex_WMM WMM_only
RTN2	FAM210B	0.008	0.025	bioplex_WMM WMM_only
SH3PXD2A	ARL6IP1	0.008	0.013	WMM_only bioplex_WMM
SH3PXD2A	RABAC1	0.008	0.013	WMM_only bioplex_WMM
DERL2	TMEM208	0.008	0.013	bioplex_WMM WMM_only
ATL3	RABAC1	0.008	0.013	bioplex_WMM WMM_only
RTN3	ATP1B2	0.008	0.014	bioplex_WMM WMM_only
CYB5R3	SPOPL	0.007	0.005	bioplex_WMM WMM_only
CYB5R3	ATP1B2	0.007	0.011	bioplex_WMM WMM_only
SH3PXD2A	ATP1B2	0.007	0.011	WMM_only bioplex_WMM
TMEM208	SPOP	0.007	0.004	bioplex_WMM WMM_only
FAM210B	RTN3	0.007	0.005	bioplex_WMM WMM_only
SH3PXD2A	SPOP	0.007	0.012	WMM_only bioplex_WMM
SH3PXD2A	ATL3	0.007	0.012	WMM_only bioplex_WMM
SH3PXD2A	FAM210B	0.007	0.008	WMM_only bioplex_WMM
FAM210B	ARL6IP1	0.007	0.008	WMM_only bioplex_WMM
TM9SF1	SPOPL	0.007	0.012	bioplex_WMM WMM_only
CYB5R3	ARL6IP1	0.007	0.01	bioplex_WMM WMM_only
CYB5R3	RABAC1	0.007	0.009	bioplex_WMM WMM_only
SH3PXD2A	RTN2	0.007	0.015	WMM_only bioplex_WMM
ATL3	SPOP	0.007	0.004	bioplex_WMM WMM_only
DERL2	ARL6IP1	0.007	0.006	bioplex_WMM WMM_only
FAM210B	ATP1B2	0.007	0.007	WMM_only bioplex_WMM
CYB5R3	SH3PXD2A	0.007	0.007	WMM_only bioplex_WMM
RTN2	SPOP	0.007	0.007	bioplex_WMM WMM_only
TM9SF1	FAM210B	0.007	0.012	bioplex_WMM WMM_only
TM9SF1	TMEM208	0.007	0.005	bioplex_WMM WMM_only
TM9SF1	RTN2	0.007	0.004	bioplex (RTN2) bioplex_WMM
FAM210B	SPOP	0.007	0.005	WMM_only bioplex_WMM
ATL3	FAM210B	0.007	0.005	WMM_only bioplex_WMM
SH3PXD2A	DERL2	0.007	0.005	WMM_only bioplex_WMM
TM9SF1	ATP1B2	0.007	0.002	bioplex_WMM WMM_only
DERL2	SPOPL	0.007	0.006	bioplex_WMM WMM_only
TM9SF1	RTN3	0.007	0.007	bioplex_WMM WMM_only boldt_WMM
ATL3	RTN2	0.007	0.006	bioplex_WMM WMM_only
SPOP	RTN3	0.007	0.002	bioplex_WMM WMM_only
CYB5R3	TMEM208	0.007	0.001	bioplex_WMM WMM_only
DERL2	ATP1B2	0.007	0.003	bioplex_WMM WMM_only
CYB5R3	SPOP	0.007	0.002	bioplex_WMM WMM_only
DERL2	RABAC1	0.007	0.001	bioplex_WMM WMM_only
SH3PXD2A	RTN3	0.007	0.0	WMM_only treiber_WMM
DHCR24	SPOP	0.007	0.0	bioplex_WMM WMM_only
DHCR24	ATP1B2	0.007	0.004	bioplex_WMM WMM_only
DHCR24	SPOPL	0.007	0.004	bioplex_WMM WMM_only
TM9SF1	RABAC1	0.007	0.004	bioplex_WMM WMM_only
CYB5R3	ATL3	0.007	0.005	bioplex_WMM WMM_only boldt_WMM treiber_WMM
TMEM208	DHCR24	0.007	0.003	bioplex_WMM WMM_only
DHCR24	ARL6IP1	0.007	0.007	bioplex_WMM WMM_only
RABAC1	DHCR24	0.007	0.005	bioplex_WMM WMM_only
TM9SF1	SPOP	0.007	0.001	bioplex_WMM WMM_only
CYB5R3	RTN2	0.007	0.008	bioplex_WMM WMM_only
CYB5R3	RTN3	0.007	0.003	bioplex_WMM gupta_WMM fraction treiber_WMM
ATL3	RTN3	0.007	0.008	hein_WMM bioplex_WMM hein (ATL3)
DERL2	SPOP	0.007	0.004	bioplex_WMM WMM_only
DERL2	FAM210B	0.007	0.007	bioplex_WMM WMM_only
TM9SF1	ATL3	0.006	0.007	bioplex_WMM WMM_only
DHCR24	RTN3	0.006	0.008	bioplex_WMM gupta_WMM WMM_only boldt_WMM
RTN2	DHCR24	0.006	0.005	bioplex_WMM WMM_only
DERL2	RTN3	0.006	0.005	bioplex_WMM gupta_WMM WMM_only boldt_WMM
DERL2	RTN2	0.006	0.002	bioplex_WMM WMM_only
ATL3	DHCR24	0.006	0.003	bioplex_WMM WMM_only boldt_WMM
CYB5R3	TM9SF1	0.006	0.011	bioplex_WMM WMM_only
CYB5R3	DHCR24	0.006	0.01	bioplex_WMM boldt gupta_WMM boldt_WMM
DERL2	ATL3	0.005	0.008	bioplex_WMM WMM_only
DERL2	DHCR24	0.005	0.01	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
CYB5R3	DERL2	0.005	0.011	bioplex_WMM gupta_WMM WMM_only

Images

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Complex HuMAP2_05832 has an average edge precision of 0.078 which is ranked 6965 out of all 6965 complexes.

Related Complexes

Genename	Complexes
DERL2	HuMAP2_01801 HuMAP2_02408 HuMAP2_05832
SH3PXD2A	HuMAP2_01786 HuMAP2_02658 HuMAP2_02666 HuMAP2_03684 HuMAP2_03765 HuMAP2_04492 HuMAP2_05832
RTN4	HuMAP2_05832 HuMAP2_05916
ARL6IP1	HuMAP2_05832 HuMAP2_05916
RTN3	HuMAP2_05832
RABAC1	HuMAP2_03643 HuMAP2_05832 HuMAP2_06386
FAM210B	HuMAP2_03643 HuMAP2_05832
DHCR24	HuMAP2_05832
CYB5R3	HuMAP2_00523 HuMAP2_03055 HuMAP2_03118 HuMAP2_05832
RTN2	HuMAP2_02998 HuMAP2_05832 HuMAP2_06445 HuMAP2_06879
TMEM208	HuMAP2_04240 HuMAP2_05832 HuMAP2_06445
SPOPL	HuMAP2_05832
SPOP	HuMAP2_05832 HuMAP2_05900
TM9SF1	HuMAP2_01441 HuMAP2_02886 HuMAP2_05832
ATL3	HuMAP2_02702 HuMAP2_05832
ATP1B2	HuMAP2_05832

hu.MAP 2.0: Complex View

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Complex: HuMAP2_05832