hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05849
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC30A7 | Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2) | UniProt NCBI |
| CHEK1 | Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1) | UniProt NCBI |
| NAT9 | N-acetyltransferase 9 (EC 2.3.1.-) (Embryo brain-specific protein) | UniProt NCBI |
| TIMM29 | Mitochondrial import inner membrane translocase subunit Tim29 (TIM29) | UniProt NCBI |
| TP53I13 | Tumor protein p53-inducible protein 13 (Damage-stimulated cytoplasmic protein 1) | UniProt NCBI |
| CHRNA9 | Neuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9) | UniProt NCBI |
| SLC30A1 | Zinc transporter 1 (ZnT-1) (Solute carrier family 30 member 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-435368 | 0.000474522632096 | 0.285714285714 | SLC30A7 SLC30A1 | Zinc efflux and compartmentalization by the SLC30 family |
| WP:WP3529 | 0.00253615815428 | 0.285714285714 | SLC30A7 SLC30A1 | Zinc homeostasis |
| REAC:R-HSA-435354 | 0.00331497172198 | 0.285714285714 | SLC30A7 SLC30A1 | Zinc transporters |
| REAC:R-HSA-425410 | 0.00662104130949 | 0.285714285714 | SLC30A7 SLC30A1 | Metal ion SLC transporters |
| CORUM:6584 | 0.0249993571594 | 0.142857142857 | CHRNA9 | CHRNA9-CHRNA10 complex |
| CORUM:2171 | 0.0499886427319 | 0.142857142857 | CHEK1 | Ubiquitin E3 ligase (CHEK1, CUL4A) |
| CORUM:2714 | 0.0499886427319 | 0.142857142857 | CHEK1 | Ubiquitin E3 ligase (CHEK1, CUL1) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHEK1 | CHRNA9 | 0.393 | 0.556 | bioplex (CHRNA9) bioplex_WMM |
| TIMM29 | CHRNA9 | 0.081 | 0.351 | bioplex (CHRNA9) bioplex_WMM |
| SLC30A1 | CHRNA9 | 0.031 | 0.239 | bioplex (CHRNA9) bioplex_WMM |
| TP53I13 | CHRNA9 | 0.023 | 0.207 | bioplex (CHRNA9) bioplex_WMM |
| SLC30A7 | CHRNA9 | 0.021 | 0.194 | bioplex (CHRNA9) bioplex_WMM |
| CHEK1 | NAT9 | 0.02 | 0.184 | bioplex (NAT9) bioplex_WMM |
| SLC30A1 | TP53I13 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| CHEK1 | TP53I13 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| TIMM29 | TP53I13 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| SLC30A7 | TP53I13 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| CHEK1 | SLC30A1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| SLC30A1 | TIMM29 | 0.006 | 0.001 | bioplex_WMM WMM_only |
| CHEK1 | TIMM29 | 0.006 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| SLC30A1 | SLC30A7 | 0.006 | 0.006 | bioplex_WMM gupta_WMM WMM_only |
| CHEK1 | SLC30A7 | 0.005 | 0.013 | bioplex_WMM WMM_only |
| TIMM29 | SLC30A7 | 0.005 | 0.009 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05849 has an average edge precision of 0.112 which is ranked 6904 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC30A7 | HuMAP2_05849 HuMAP2_06418 HuMAP2_06539 |
| CHEK1 | HuMAP2_01371 HuMAP2_05132 HuMAP2_05849 HuMAP2_06351 HuMAP2_06418 |
| NAT9 | HuMAP2_01371 HuMAP2_05132 HuMAP2_05849 HuMAP2_06418 |
| TIMM29 | HuMAP2_05805 HuMAP2_05849 HuMAP2_06351 HuMAP2_06418 HuMAP2_06539 |
| TP53I13 | HuMAP2_05849 HuMAP2_06418 HuMAP2_06539 |
| CHRNA9 | HuMAP2_05849 HuMAP2_06351 HuMAP2_06418 HuMAP2_06539 |
| SLC30A1 | HuMAP2_03413 HuMAP2_04899 HuMAP2_05849 |