hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05873
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ADSS2 | Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2) | UniProt NCBI |
| ADSS1 | Adenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC 6.3.4.4) (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (IMP--aspartate ligase 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00250 | 7.70339033036e-05 | 1.0 | ADSS2 ADSS1 | Alanine, aspartate and glutamate metabolism |
| REAC:R-HSA-73817 | 0.000110610948517 | 1.0 | ADSS2 ADSS1 | Purine ribonucleoside monophosphate biosynthesis |
| REAC:R-HSA-8956320 | 0.000175971963549 | 1.0 | ADSS2 ADSS1 | Nucleobase biosynthesis |
| GO:0004019 | 0.000450823411379 | 1.0 | ADSS2 ADSS1 | adenylosuccinate synthase activity |
| KEGG:00230 | 0.000890704506947 | 1.0 | ADSS2 ADSS1 | Purine metabolism |
| GO:0044208 | 0.00135247023414 | 1.0 | ADSS2 ADSS1 | 'de novo' AMP biosynthetic process |
| GO:0006167 | 0.00270494046827 | 1.0 | ADSS2 ADSS1 | AMP biosynthetic process |
| REAC:R-HSA-15869 | 0.00612550025498 | 1.0 | ADSS2 ADSS1 | Metabolism of nucleotides |
| GO:0046040 | 0.0126230555186 | 1.0 | ADSS2 ADSS1 | IMP metabolic process |
| GO:0042301 | 0.0162296428096 | 1.0 | ADSS2 ADSS1 | phosphate ion binding |
| GO:0046033 | 0.020287053512 | 1.0 | ADSS2 ADSS1 | AMP metabolic process |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ADSS2 | ADSS1 | 1.0 | 0.949 | bioplex (ADSS2) bioplex_WMM |
Images
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Complex HuMAP2_05873 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ADSS2 | HuMAP2_00546 HuMAP2_01426 HuMAP2_05873 HuMAP2_05943 HuMAP2_06767 |
| ADSS1 | HuMAP2_00570 HuMAP2_03217 HuMAP2_05130 HuMAP2_05873 |