hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05879
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP6AP2 | Renin receptor (ATPase H(+)-transporting lysosomal accessory protein 2) (ATPase H(+)-transporting lysosomal-interacting protein 2) (ER-localized type I transmembrane adaptor) (Embryonic liver differentiation factor 10) (N14F) (Renin/prorenin receptor) (Vacuolar ATP synthase membrane sector-associated protein M8-9) (ATP6M8-9) (V-ATPase M8.9 subunit) | UniProt NCBI |
| BIRC7 | Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)] | UniProt NCBI |
| TMUB1 | Transmembrane and ubiquitin-like domain-containing protein 1 (Dendritic cell-derived ubiquitin-like protein) (DULP) (Hepatocyte odd protein shuttling protein) (Ubiquitin-like protein SB144) [Cleaved into: iHOPS] | UniProt NCBI |
| SLC38A2 | Sodium-coupled neutral amino acid transporter 2 (Amino acid transporter A2) (Protein 40-9-1) (Solute carrier family 38 member 2) (System A amino acid transporter 2) (System A transporter 1) (System N amino acid transporter 2) | UniProt NCBI |
| OSTM1 | Osteopetrosis-associated transmembrane protein 1 (Chloride channel 7 beta subunit) | UniProt NCBI |
| TCIRG1 | V-type proton ATPase 116 kDa subunit a isoform 3 (V-ATPase 116 kDa isoform a3) (Osteoclastic proton pump 116 kDa subunit) (OC-116 kDa) (OC116) (T-cell immune regulator 1) (T-cell immune response cDNA7 protein) (TIRC7) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3) | UniProt NCBI |
| JPH1 | Junctophilin-1 (JP-1) (Junctophilin type 1) | UniProt NCBI |
| MITD1 | MIT domain-containing protein 1 | UniProt NCBI |
| TFRC | Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] | UniProt NCBI |
| XPNPEP3 | Xaa-Pro aminopeptidase 3 (X-Pro aminopeptidase 3) (EC 3.4.11.9) (Aminopeptidase P3) (APP3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0005425 | 0.0193356219159 | 0.2 | TCIRG1 TFRC | Recurrent sinopulmonary infections |
| HP:0011002 | 0.0266406279253 | 0.2 | TCIRG1 OSTM1 | Osteopetrosis |
| REAC:R-HSA-917977 | 0.0341308097173 | 0.2 | TCIRG1 TFRC | Transferrin endocytosis and recycling |
| MIRNA:hsa-miR-6895-3p | 0.04115062048 | 0.3 | OSTM1 TFRC XPNPEP3 | hsa-miR-6895-3p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP6AP2 | MITD1 | 0.062 | 0.342 | hein_WMM hein (ATP6AP2) |
| ATP6AP2 | SLC38A2 | 0.051 | 0.296 | hein_WMM bioplex_WMM hein (ATP6AP2) gupta_WMM |
| OSTM1 | ATP6AP2 | 0.044 | 0.279 | hein_WMM bioplex_WMM hein (ATP6AP2) |
| ATP6AP2 | TCIRG1 | 0.041 | 0.271 | bioplex (ATP6AP2) bioplex_WMM |
| ATP6AP2 | TMUB1 | 0.04 | 0.267 | hein_WMM bioplex_WMM hein (ATP6AP2) |
| BIRC7 | OSTM1 | 0.031 | 0.239 | bioplex (BIRC7) bioplex_WMM |
| ATP6AP2 | JPH1 | 0.027 | 0.227 | hein_WMM bioplex_WMM youn_WMM hein (ATP6AP2) gupta_WMM |
| TFRC | ATP6AP2 | 0.027 | 0.223 | hein_WMM bioplex (ATP6AP2) bioplex_WMM youn_WMM hein (ATP6AP2) gupta_WMM |
| BIRC7 | XPNPEP3 | 0.022 | 0.208 | bioplex (BIRC7) bioplex_WMM |
| TFRC | SLC38A2 | 0.007 | 0.005 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| OSTM1 | TMUB1 | 0.007 | 0.002 | hein_WMM WMM_only |
| OSTM1 | SLC38A2 | 0.007 | 0.01 | hein_WMM bioplex_WMM WMM_only |
| OSTM1 | JPH1 | 0.007 | 0.009 | hein_WMM WMM_only |
| OSTM1 | MITD1 | 0.007 | 0.004 | hein_WMM WMM_only |
| TFRC | OSTM1 | 0.007 | 0.003 | hein_WMM WMM_only |
| XPNPEP3 | ATP6AP2 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| XPNPEP3 | TMUB1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| TCIRG1 | TMUB1 | 0.007 | 0.006 | hein_WMM WMM_only |
| XPNPEP3 | OSTM1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TCIRG1 | SLC38A2 | 0.007 | 0.007 | hein_WMM WMM_only |
| TFRC | TCIRG1 | 0.007 | 0.002 | hein_WMM bioplex_WMM WMM_only |
| TFRC | XPNPEP3 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| MITD1 | JPH1 | 0.006 | 0.009 | hein_WMM WMM_only |
| TFRC | JPH1 | 0.006 | 0.004 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MITD1 | TMUB1 | 0.006 | 0.006 | hein_WMM WMM_only |
| XPNPEP3 | JPH1 | 0.006 | 0.004 | bioplex_WMM WMM_only |
| XPNPEP3 | SLC38A2 | 0.006 | 0.003 | bioplex_WMM WMM_only |
| TFRC | TMUB1 | 0.006 | 0.007 | hein_WMM bioplex_WMM WMM_only |
| MITD1 | SLC38A2 | 0.006 | 0.003 | hein_WMM WMM_only |
| JPH1 | TMUB1 | 0.006 | 0.005 | hein_WMM bioplex_WMM WMM_only |
| SLC38A2 | JPH1 | 0.006 | 0.008 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| TFRC | MITD1 | 0.005 | 0.01 | hein_WMM WMM_only |
| SLC38A2 | TMUB1 | 0.004 | 0.012 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05879 has an average edge precision of 0.075 which is ranked 6966 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP6AP2 | HuMAP2_00515 HuMAP2_01018 HuMAP2_01270 HuMAP2_04327 HuMAP2_05361 HuMAP2_05879 HuMAP2_06410 |
| BIRC7 | HuMAP2_00392 HuMAP2_01437 HuMAP2_01596 HuMAP2_03984 HuMAP2_05879 HuMAP2_06122 |
| TMUB1 | HuMAP2_05879 HuMAP2_06386 |
| SLC38A2 | HuMAP2_01018 HuMAP2_05879 HuMAP2_06410 |
| OSTM1 | HuMAP2_00392 HuMAP2_01437 HuMAP2_05879 HuMAP2_06410 |
| TCIRG1 | HuMAP2_01018 HuMAP2_01270 HuMAP2_05879 |
| JPH1 | HuMAP2_02734 HuMAP2_05879 |
| MITD1 | HuMAP2_01018 HuMAP2_05879 HuMAP2_06410 |
| TFRC | HuMAP2_00382 HuMAP2_01484 HuMAP2_05879 |
| XPNPEP3 | HuMAP2_00392 HuMAP2_01437 HuMAP2_01819 HuMAP2_03984 HuMAP2_04023 HuMAP2_05879 |