hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05887
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FOXK2 | Forkhead box protein K2 (G/T-mismatch specific binding protein) (nGTBP) (Interleukin enhancer-binding factor 1) | UniProt NCBI |
| FOXK1 | Forkhead box protein K1 (Myocyte nuclear factor) (MNF) | UniProt NCBI |
| DVL3 | Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3) | UniProt NCBI |
| NXN | Nucleoredoxin (EC 1.8.1.8) | UniProt NCBI |
| EPB41L4A | Band 4.1-like protein 4A (Protein NBL4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0100798 | 0.0025531267598 | 0.4 | DVL3 NXN | Fingernail dysplasia |
| HP:0010297 | 0.0107072942689 | 0.4 | DVL3 NXN | Bifid tongue |
| GO:0035947 | 0.0135228859698 | 0.4 | FOXK2 FOXK1 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter |
| HP:0003027 | 0.0162585949147 | 0.4 | DVL3 NXN | Mesomelia |
| HP:0001052 | 0.0244376541782 | 0.4 | DVL3 NXN | Nevus flammeus |
| HP:0011069 | 0.0259615168254 | 0.4 | DVL3 NXN | Increased number of teeth |
| HP:0025104 | 0.0291468055875 | 0.4 | DVL3 NXN | Capillary malformation |
| HP:0010807 | 0.0308081945037 | 0.4 | DVL3 NXN | Open bite |
| HP:0004397 | 0.0342683684383 | 0.4 | DVL3 NXN | Ectopic anus |
| MIRNA:hsa-miR-6830-5p | 0.0466750398091 | 0.4 | DVL3 FOXK1 | hsa-miR-6830-5p |
| HP:0012815 | 0.0478196851342 | 0.4 | DVL3 NXN | Hypoplastic female external genitalia |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DVL3 | EPB41L4A | 0.236 | 0.469 | bioplex (DVL3) bioplex_WMM |
| DVL3 | FOXK2 | 0.048 | 0.295 | bioplex (DVL3) bioplex_WMM youn_WMM |
| NXN | DVL3 | 0.047 | 0.293 | bioplex (DVL3) bioplex_WMM youn_WMM gupta_WMM |
| FOXK1 | FOXK2 | 0.044 | 0.279 | hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM |
| FOXK1 | DVL3 | 0.02 | 0.185 | bioplex (DVL3) bioplex_WMM youn_WMM |
| FOXK2 | EPB41L4A | 0.008 | 0.037 | bioplex_WMM WMM_only |
| NXN | EPB41L4A | 0.008 | 0.032 | bioplex_WMM WMM_only |
| FOXK1 | EPB41L4A | 0.008 | 0.013 | bioplex_WMM WMM_only |
| NXN | FOXK2 | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| FOXK1 | NXN | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_05887 has an average edge precision of 0.161 which is ranked 6622 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FOXK2 | HuMAP2_04648 HuMAP2_05887 HuMAP2_06664 |
| FOXK1 | HuMAP2_00920 HuMAP2_05887 HuMAP2_06664 |
| DVL3 | HuMAP2_03933 HuMAP2_04648 HuMAP2_05887 HuMAP2_06664 |
| NXN | HuMAP2_01216 HuMAP2_05887 HuMAP2_06664 |
| EPB41L4A | HuMAP2_04648 HuMAP2_05887 HuMAP2_06664 |