hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05890
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PLEKHO2 | Pleckstrin homology domain-containing family O member 2 (PH domain-containing family O member 2) (Pleckstrin homology domain-containing family Q member 1) (PH domain-containing family Q member 1) | UniProt NCBI |
| CAPZB | F-actin-capping protein subunit beta (CapZ beta) | UniProt NCBI |
| CAPZA1 | F-actin-capping protein subunit alpha-1 (CapZ alpha-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6483 | 3.35600554376e-06 | 0.666666666667 | CAPZB CAPZA1 | CAPZalpha-CAPZbeta complex |
| CORUM:846 | 7.04603414803e-05 | 0.666666666667 | CAPZB CAPZA1 | RICH1/AMOT polarity complex, Flag-Rich1 precipitated |
| CORUM:6484 | 7.04603414803e-05 | 0.666666666667 | CAPZB CAPZA1 | WASH-CAPZalpa/beta complex |
| CORUM:6671 | 0.000305232445119 | 0.666666666667 | CAPZB CAPZA1 | PI4K2A-WASH complex |
| REAC:R-HSA-6811436 | 0.00818423736949 | 0.666666666667 | CAPZB CAPZA1 | COPI-independent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-3371497 | 0.008858224502 | 0.666666666667 | CAPZB CAPZA1 | HSP90 chaperone cycle for steroid hormone receptors (SHR) |
| KEGG:04144 | 0.0117748506163 | 0.666666666667 | CAPZB CAPZA1 | Endocytosis |
| REAC:R-HSA-6807878 | 0.03104119222 | 0.666666666667 | CAPZB CAPZA1 | COPI-mediated anterograde transport |
| GO:0008290 | 0.0378589948753 | 0.666666666667 | CAPZB CAPZA1 | F-actin capping protein complex |
| REAC:R-HSA-2132295 | 0.0444303896492 | 0.666666666667 | CAPZB CAPZA1 | MHC class II antigen presentation |
| CORUM:7002 | 0.0499776345577 | 0.333333333333 | CAPZB | CAPZA3-CAPZB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CAPZB | CAPZA1 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| PLEKHO2 | CAPZA1 | 0.812 | 0.771 | bioplex (PLEKHO2) bioplex_WMM |
| PLEKHO2 | CAPZB | 0.753 | 0.747 | bioplex (PLEKHO2) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_05890 has an average edge precision of 0.822 which is ranked 863 out of all 6965 complexes.
Related Complexes