hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05891
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEMG1 | Semenogelin-1 (Cancer/testis antigen 103) (Semenogelin I) (SGI) [Cleaved into: Alpha-inhibin-92; Alpha-inhibin-31; Seminal basic protein] | UniProt NCBI |
| HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 1) (HACD1) (Cementum-attachment protein) (CAP) (Protein-tyrosine phosphatase-like member A) | UniProt NCBI |
| MSS51 | Putative protein MSS51 homolog, mitochondrial (Zinc finger MYND domain-containing protein 17) | UniProt NCBI |
| NUPR1 | Nuclear protein 1 (Candidate of metastasis 1) (Protein p8) | UniProt NCBI |
| SYN2 | Synapsin-2 (Synapsin II) | UniProt NCBI |
| POLL | DNA polymerase lambda (Pol Lambda) (EC 2.7.7.7) (EC 4.2.99.-) (DNA polymerase beta-2) (Pol beta2) (DNA polymerase kappa) | UniProt NCBI |
| SEMG2 | Semenogelin-2 (Semenogelin II) (SGII) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1900005 | 0.00946729163895 | 0.285714285714 | SEMG1 SEMG2 | positive regulation of serine-type endopeptidase activity |
| GO:1902573 | 0.00946729163895 | 0.285714285714 | SEMG1 SEMG2 | positive regulation of serine-type peptidase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SEMG1 | POLL | 0.162 | 0.42 | bioplex (POLL) bioplex_WMM |
| SYN2 | POLL | 0.11 | 0.379 | bioplex (POLL) bioplex_WMM |
| NUPR1 | SEMG2 | 0.084 | 0.349 | bioplex (NUPR1) bioplex_WMM |
| SEMG1 | NUPR1 | 0.064 | 0.349 | bioplex (NUPR1) bioplex_WMM |
| SEMG1 | SEMG2 | 0.036 | 0.265 | bioplex_WMM boldt boldt_WMM treiber_WMM |
| SEMG1 | HACD1 | 0.029 | 0.23 | bioplex (HACD1) bioplex_WMM |
| SEMG2 | POLL | 0.027 | 0.23 | bioplex (POLL) bioplex_WMM |
| SEMG1 | MSS51 | 0.023 | 0.208 | bioplex (MSS51) bioplex_WMM |
| SEMG2 | MSS51 | 0.022 | 0.195 | bioplex (MSS51) bioplex_WMM |
| SEMG2 | HACD1 | 0.012 | 0.15 | bioplex (HACD1) bioplex_WMM |
| SEMG2 | SYN2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| SEMG1 | SYN2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05891 has an average edge precision of 0.232 which is ranked 5657 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEMG1 | HuMAP2_01459 HuMAP2_05474 HuMAP2_05891 |
| HACD1 | HuMAP2_05891 |
| MSS51 | HuMAP2_05891 |
| NUPR1 | HuMAP2_01459 HuMAP2_05474 HuMAP2_05891 |
| SYN2 | HuMAP2_03583 HuMAP2_05891 |
| POLL | HuMAP2_03583 HuMAP2_04114 HuMAP2_04306 HuMAP2_05891 |
| SEMG2 | HuMAP2_01459 HuMAP2_03909 HuMAP2_05474 HuMAP2_05891 |