hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05892
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MTAP | S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) (5'-methylthioadenosine phosphorylase) (MTA phosphorylase) (MTAP) (MTAPase) | UniProt NCBI |
| IQGAP2 | Ras GTPase-activating-like protein IQGAP2 | UniProt NCBI |
| SUCLA2 | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial (EC 6.2.1.5) (ATP-specific succinyl-CoA synthetase subunit beta) (A-SCS) (Succinyl-CoA synthetase beta-A chain) (SCS-betaA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:394 | 0.0499776345577 | 0.333333333333 | SUCLA2 | Succinyl-CoA synthetase, ADP-forming |
| WP:WP4236 | 0.0499785733994 | 0.333333333333 | SUCLA2 | Disorders of the Krebs cycle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MTAP | SUCLA2 | 0.137 | 0.406 | bioplex_WMM fraction |
| SUCLA2 | IQGAP2 | 0.025 | 0.211 | bioplex (SUCLA2) bioplex_WMM boldt boldt_WMM |
| MTAP | IQGAP2 | 0.007 | 0.005 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_05892 has an average edge precision of 0.207 which is ranked 6075 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MTAP | HuMAP2_00179 HuMAP2_05892 |
| IQGAP2 | HuMAP2_04460 HuMAP2_05892 |
| SUCLA2 | HuMAP2_00179 HuMAP2_03050 HuMAP2_03427 HuMAP2_04460 HuMAP2_05892 |