hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05893
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TANK | TRAF family member-associated NF-kappa-B activator (TRAF-interacting protein) (I-TRAF) | UniProt NCBI |
| TRAF2 | TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2) (Tumor necrosis factor type 2 receptor-associated protein 3) | UniProt NCBI |
| LAMC3 | Laminin subunit gamma-3 (Laminin-12 subunit gamma) (Laminin-14 subunit gamma) (Laminin-15 subunit gamma) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5210 | 1.00675659188e-05 | 0.666666666667 | TANK TRAF2 | TANK-TRAF2-TRAF3 complex |
| CORUM:5212 | 9.39429153233e-05 | 0.666666666667 | TANK TRAF2 | Kinase maturation complex 2 |
| KEGG:04622 | 0.000900335185999 | 0.666666666667 | TANK TRAF2 | RIG-I-like receptor signaling pathway |
| WP:WP3865 | 0.00136941813981 | 0.666666666667 | TANK TRAF2 | Novel intracellular components of RIG-I-like receptor (RLR) pathway |
| KEGG:05222 | 0.00186709616111 | 0.666666666667 | LAMC3 TRAF2 | Small cell lung cancer |
| REAC:R-HSA-933541 | 0.00271504560844 | 0.666666666667 | TANK TRAF2 | TRAF6 mediated IRF7 activation |
| WP:WP231 | 0.00365767654025 | 0.666666666667 | TANK TRAF2 | TNF alpha Signaling Pathway |
| WP:WP4658 | 0.00426499169434 | 0.666666666667 | LAMC3 TRAF2 | Small cell lung cancer |
| KEGG:04621 | 0.00551574183542 | 0.666666666667 | TANK TRAF2 | NOD-like receptor signaling pathway |
| REAC:R-HSA-168928 | 0.0170598073203 | 0.666666666667 | TANK TRAF2 | DDX58/IFIH1-mediated induction of interferon-alpha/beta |
| KEGG:05200 | 0.0473113658041 | 0.666666666667 | LAMC3 TRAF2 | Pathways in cancer |
| CORUM:2744 | 0.0499776345577 | 0.333333333333 | TRAF2 | TRAF2-MALT1 complex |
| CORUM:5529 | 0.0499776345577 | 0.333333333333 | TRAF2 | TRAF2-cIAP1/BIRC2 complex |
| CORUM:5540 | 0.0499776345577 | 0.333333333333 | TRAF2 | TRAF2-TRADD complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TANK | TRAF2 | 0.086 | 0.351 | bioplex (TRAF2) bioplex_WMM |
| LAMC3 | TRAF2 | 0.03 | 0.231 | fraction |
Images
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Complex HuMAP2_05893 has an average edge precision of 0.291 which is ranked 4735 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TANK | HuMAP2_01807 HuMAP2_02471 HuMAP2_02920 HuMAP2_03079 HuMAP2_05715 HuMAP2_05893 |
| TRAF2 | HuMAP2_01807 HuMAP2_05715 HuMAP2_05893 |
| LAMC3 | HuMAP2_01807 HuMAP2_05893 |