hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05901
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GSTA1 | Glutathione S-transferase A1 (EC 2.5.1.18) (13-hydroperoxyoctadecadienoate peroxidase) (EC 1.11.1.-) (Androst-5-ene-3,17-dione isomerase) (EC 5.3.3.-) (GST HA subunit 1) (GST class-alpha member 1) (GST-epsilon) (GSTA1-1) (GTH1) [Cleaved into: Glutathione S-transferase A1, N-terminally processed] | UniProt NCBI |
| GSTA3 | Glutathione S-transferase A3 (EC 2.5.1.18) (GST class-alpha member 3) (Glutathione S-transferase A3-3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00480 | 0.000171575511903 | 1.0 | GSTA1 GSTA3 | Glutathione metabolism |
| KEGG:00982 | 0.00025823865312 | 1.0 | GSTA1 GSTA3 | Drug metabolism - cytochrome P450 |
| KEGG:00980 | 0.000294129448977 | 1.0 | GSTA1 GSTA3 | Metabolism of xenobiotics by cytochrome P450 |
| KEGG:05204 | 0.000342275638542 | 1.0 | GSTA1 GSTA3 | Chemical carcinogenesis |
| KEGG:00983 | 0.00037291412281 | 1.0 | GSTA1 GSTA3 | Drug metabolism - other enzymes |
| KEGG:01524 | 0.00037291412281 | 1.0 | GSTA1 GSTA3 | Platinum drug resistance |
| REAC:R-HSA-156590 | 0.000940193062392 | 1.0 | GSTA1 GSTA3 | Glutathione conjugation |
| KEGG:05418 | 0.00113070596705 | 1.0 | GSTA1 GSTA3 | Fluid shear stress and atherosclerosis |
| KEGG:05225 | 0.00183261905189 | 1.0 | GSTA1 GSTA3 | Hepatocellular carcinoma |
| WP:WP2884 | 0.00227460903014 | 1.0 | GSTA1 GSTA3 | NRF2 pathway |
| WP:WP702 | 0.00467999410771 | 1.0 | GSTA1 GSTA3 | Metapathway biotransformation Phase I and II |
| REAC:R-HSA-156580 | 0.0074829982595 | 1.0 | GSTA1 GSTA3 | Phase II - Conjugation of compounds |
| WP:WP2882 | 0.0123521888904 | 1.0 | GSTA1 GSTA3 | Nuclear Receptors Meta-Pathway |
| KEGG:05200 | 0.0157394270613 | 1.0 | GSTA1 GSTA3 | Pathways in cancer |
| REAC:R-HSA-211859 | 0.0291459849342 | 1.0 | GSTA1 GSTA3 | Biological oxidations |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GSTA1 | GSTA3 | 1.0 | 0.949 | bioplex (GSTA1) bioplex_WMM |
Images
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Complex HuMAP2_05901 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| GSTA1 | HuMAP2_00794 HuMAP2_05901 |
| GSTA3 | HuMAP2_00794 HuMAP2_05901 |