hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05903
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FARSB | Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS) | UniProt NCBI |
| FARSA | Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (CML33) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS) | UniProt NCBI |
| POU2F1 | POU domain, class 2, transcription factor 1 (NF-A1) (Octamer-binding protein 1) (Oct-1) (Octamer-binding transcription factor 1) (OTF-1) | UniProt NCBI |
| ARFGAP2 | ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289) | UniProt NCBI |
| SAMHD1 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (dNTPase) (EC 3.1.5.-) (Dendritic cell-derived IFNG-induced protein) (DCIP) (Monocyte protein 5) (MOP-5) (SAM domain and HD domain-containing protein 1) (hSAMHD1) | UniProt NCBI |
| IRF2BP1 | Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00970 | 0.00587890830807 | 0.333333333333 | FARSA FARSB | Aminoacyl-tRNA biosynthesis |
| REAC:R-HSA-379716 | 0.0060953046166 | 0.333333333333 | FARSA FARSB | Cytosolic tRNA aminoacylation |
| GO:0009328 | 0.00676235117068 | 0.333333333333 | FARSA FARSB | phenylalanine-tRNA ligase complex |
| REAC:R-HSA-379724 | 0.0189534530409 | 0.333333333333 | FARSA FARSB | tRNA Aminoacylation |
| GO:0006432 | 0.020283420769 | 0.333333333333 | FARSA FARSB | phenylalanyl-tRNA aminoacylation |
| GO:0004826 | 0.0405595771497 | 0.333333333333 | FARSA FARSB | phenylalanine-tRNA ligase activity |
| CORUM:2802 | 0.0499726005494 | 0.166666666667 | POU2F1 | OCT1-SOX2 DNA-protein complex |
| CORUM:3122 | 0.0499726005494 | 0.166666666667 | POU2F1 | OCT1-OBF1-DNA complex |
| CORUM:3132 | 0.0499726005494 | 0.166666666667 | POU2F1 | OCT1-OBF1-DNA complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FARSA | FARSB | 0.996 | 0.928 | bioplex (FARSA) bioplex_WMM Guru youn_WMM Malo gupta_WMM fraction treiber_WMM |
| FARSA | SAMHD1 | 0.268 | 0.483 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ARFGAP2 | POU2F1 | 0.124 | 0.395 | fraction boldt_WMM |
| IRF2BP1 | ARFGAP2 | 0.113 | 0.382 | boldt youn_WMM fraction boldt_WMM |
| POU2F1 | FARSB | 0.106 | 0.374 | bioplex_WMM fraction |
| IRF2BP1 | FARSB | 0.067 | 0.352 | youn_WMM fraction bioplex_WMM |
| FARSA | POU2F1 | 0.016 | 0.156 | fraction |
| SAMHD1 | FARSB | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| SAMHD1 | IRF2BP1 | 0.007 | 0.003 | youn_WMM WMM_only |
| SAMHD1 | ARFGAP2 | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| FARSA | IRF2BP1 | 0.003 | 0.017 | youn_WMM fraction |
| IRF2BP1 | POU2F1 | 0.0 | 0.015 | fraction boldt_WMM |
| ARFGAP2 | FARSB | 0.0 | 0.0 | youn_WMM gupta_WMM fraction |
| FARSA | ARFGAP2 | 0.0 | 0.001 | youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05903 has an average edge precision of 0.222 which is ranked 5820 out of all 6965 complexes.
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