hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05905
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBM45 | RNA-binding protein 45 (Developmentally-regulated RNA-binding protein 1) (RB-1) (RNA-binding motif protein 45) | UniProt NCBI |
| CTNNBIP1 | Beta-catenin-interacting protein 1 (Inhibitor of beta-catenin and Tcf-4) | UniProt NCBI |
| GSTK1 | Glutathione S-transferase kappa 1 (EC 2.5.1.18) (GST 13-13) (GST class-kappa) (GSTK1-1) (hGSTK1) (Glutathione S-transferase subunit 13) | UniProt NCBI |
| ARHGAP24 | Rho GTPase-activating protein 24 (Filamin-A-associated RhoGAP) (FilGAP) (RAC1- and CDC42-specific GTPase-activating protein of 72 kDa) (RC-GAP72) (Rho-type GTPase-activating protein 24) (RhoGAP of 73 kDa) (Sarcoma antigen NY-SAR-88) (p73RhoGAP) | UniProt NCBI |
| DKK1 | Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK) | UniProt NCBI |
| TK2 | Thymidine kinase 2, mitochondrial (EC 2.7.1.21) (Mt-TK) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4336 | 0.0165558163549 | 0.333333333333 | CTNNBIP1 DKK1 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
| WP:WP4258 | 0.0205911896387 | 0.333333333333 | CTNNBIP1 DKK1 | LncRNA involvement in canonical Wnt signaling and colorectal cancer |
| WP:WP428 | 0.0311023908548 | 0.333333333333 | CTNNBIP1 DKK1 | Wnt Signaling |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TK2 | DKK1 | 0.951 | 0.858 | bioplex (DKK1) bioplex_WMM |
| ARHGAP24 | DKK1 | 0.339 | 0.528 | bioplex (DKK1) bioplex_WMM |
| CTNNBIP1 | TK2 | 0.301 | 0.496 | bioplex (CTNNBIP1) bioplex_WMM |
| GSTK1 | TK2 | 0.077 | 0.354 | bioplex (GSTK1) bioplex_WMM |
| RBM45 | DKK1 | 0.041 | 0.271 | bioplex (DKK1) bioplex_WMM |
| TK2 | ARHGAP24 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| RBM45 | TK2 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| RBM45 | ARHGAP24 | 0.008 | 0.06 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05905 has an average edge precision of 0.34 which is ranked 4121 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RBM45 | HuMAP2_00209 HuMAP2_01508 HuMAP2_05905 HuMAP2_06363 |
| CTNNBIP1 | HuMAP2_00209 HuMAP2_02933 HuMAP2_03682 HuMAP2_05905 |
| GSTK1 | HuMAP2_00209 HuMAP2_02933 HuMAP2_03682 HuMAP2_05905 |
| ARHGAP24 | HuMAP2_00209 HuMAP2_01508 HuMAP2_02933 HuMAP2_05905 |
| DKK1 | HuMAP2_00209 HuMAP2_01508 HuMAP2_02933 HuMAP2_04047 HuMAP2_05905 |
| TK2 | HuMAP2_00209 HuMAP2_01508 HuMAP2_02933 HuMAP2_03682 HuMAP2_04047 HuMAP2_05905 |