hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05913
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MDH1 | Malate dehydrogenase, cytoplasmic (EC 1.1.1.37) (Cytosolic malate dehydrogenase) (Diiodophenylpyruvate reductase) (EC 1.1.1.96) | UniProt NCBI |
| ESD | S-formylglutathione hydrolase (FGH) (EC 3.1.2.12) (Esterase D) (Methylumbelliferyl-acetate deacetylase) (EC 3.1.1.56) | UniProt NCBI |
| SORD | Sorbitol dehydrogenase (SDH) (EC 1.1.1.-) ((R,R)-butanediol dehydrogenase) (EC 1.1.1.4) (L-iditol 2-dehydrogenase) (EC 1.1.1.14) (Polyol dehydrogenase) (Ribitol dehydrogenase) (RDH) (EC 1.1.1.56) (Xylitol dehydrogenase) (XDH) (EC 1.1.1.9) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01200 | 0.00287006078872 | 0.666666666667 | ESD MDH1 | Carbon metabolism |
| KEGG:01100 | 0.0105851300972 | 1.0 | SORD ESD MDH1 | Metabolic pathways |
| WP:WP690 | 0.0285649389616 | 0.333333333333 | SORD | Polyol Pathway |
| WP:WP136 | 0.0499785733994 | 0.333333333333 | ESD | Phase I biotransformations, non P450 |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MDH1 | SORD | 0.942 | 0.855 | bioplex_WMM fraction treiber_WMM |
| MDH1 | ESD | 0.626 | 0.679 | bioplex_WMM fraction treiber_WMM |
| ESD | SORD | 0.0 | 0.009 | bioplex_WMM fraction |
Images
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Complex HuMAP2_05913 has an average edge precision of 0.514 which is ranked 2418 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MDH1 | HuMAP2_01176 HuMAP2_04246 HuMAP2_04645 HuMAP2_05524 HuMAP2_05913 |
| ESD | HuMAP2_01455 HuMAP2_01504 HuMAP2_05913 |
| SORD | HuMAP2_05524 HuMAP2_05913 |