hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05921
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PITHD1 | PITH domain-containing protein 1 | UniProt NCBI |
| VTI1B | Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1) | UniProt NCBI |
| PTTG1IP | Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor) | UniProt NCBI |
| CWC27 | Spliceosome-associated protein CWC27 homolog (Antigen NY-CO-10) (Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog) (PPIase CWC27) (Serologically defined colon cancer antigen 10) | UniProt NCBI |
| NAPG | Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma) | UniProt NCBI |
| STX8 | Syntaxin-8 | UniProt NCBI |
| STX7 | Syntaxin-7 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04130 | 1.6429978705e-05 | 0.428571428571 | VTI1B STX8 STX7 | SNARE interactions in vesicular transport |
| GO:0031201 | 0.000138393555724 | 0.571428571429 | VTI1B NAPG STX7 STX8 | SNARE complex |
| GO:0019869 | 0.000380900357231 | 0.428571428571 | VTI1B STX8 STX7 | chloride channel inhibitor activity |
| GO:0017081 | 0.000907263777246 | 0.428571428571 | VTI1B STX8 STX7 | chloride channel regulator activity |
| GO:0000149 | 0.00205634104213 | 0.571428571429 | VTI1B NAPG STX7 STX8 | SNARE binding |
| GO:0061025 | 0.00559719590834 | 0.571428571429 | VTI1B NAPG STX7 STX8 | membrane fusion |
| GO:0008200 | 0.0115540711621 | 0.428571428571 | VTI1B STX8 STX7 | ion channel inhibitor activity |
| GO:0005484 | 0.0128352677703 | 0.428571428571 | VTI1B STX8 STX7 | SNAP receptor activity |
| GO:0016248 | 0.0128352677703 | 0.428571428571 | VTI1B STX8 STX7 | channel inhibitor activity |
| GO:0048278 | 0.0478353182304 | 0.428571428571 | VTI1B STX8 STX7 | vesicle docking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STX8 | STX7 | 0.84 | 0.784 | hein_WMM bioplex (STX7) bioplex_WMM youn_WMM gupta_WMM |
| STX7 | PTTG1IP | 0.5 | 0.621 | hein_WMM bioplex (STX7) bioplex_WMM |
| STX8 | VTI1B | 0.429 | 0.577 | hein_WMM bioplex (VTI1B) bioplex_WMM |
| NAPG | STX7 | 0.092 | 0.355 | bioplex (NAPG,STX7) bioplex_WMM |
| VTI1B | STX7 | 0.084 | 0.349 | hein_WMM bioplex (STX7,VTI1B) bioplex_WMM |
| VTI1B | CWC27 | 0.077 | 0.352 | bioplex (VTI1B) bioplex_WMM |
| PITHD1 | CWC27 | 0.073 | 0.357 | bioplex (PITHD1) bioplex_WMM fraction |
| NAPG | VTI1B | 0.064 | 0.35 | bioplex (NAPG,VTI1B) bioplex_WMM |
| NAPG | STX8 | 0.053 | 0.301 | bioplex (NAPG) bioplex_WMM |
| STX8 | PTTG1IP | 0.009 | 0.105 | hein_WMM bioplex_WMM WMM_only |
| VTI1B | PTTG1IP | 0.008 | 0.091 | hein_WMM bioplex_WMM WMM_only |
| NAPG | PTTG1IP | 0.008 | 0.082 | bioplex_WMM WMM_only |
| STX7 | CWC27 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| NAPG | CWC27 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| NAPG | PITHD1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| STX7 | PITHD1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| STX8 | PITHD1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| VTI1B | PITHD1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| STX8 | CWC27 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05921 has an average edge precision of 0.229 which is ranked 5725 out of all 6965 complexes.
Related Complexes