hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05923
Confidence: Medium  
ProteinsGenename | Protein Name | Links |
---|---|---|
GPR137 | Integral membrane protein GPR137 (Transmembrane 7 superfamily member 1-like 1 protein) | UniProt   NCBI |
SELENOT | Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9) | UniProt   NCBI |
HVCN1 | Voltage-gated hydrogen channel 1 (Hydrogen voltage-gated channel 1) (HV1) (Voltage sensor domain-only protein) | UniProt   NCBI |
ENPP4 | Bis(5'-adenosyl)-triphosphatase ENPP4 (EC 3.6.1.29) (AP3A hydrolase) (AP3Aase) (Ectonucleotide pyrophosphatase/phosphodiesterase family member 4) (E-NPP 4) (NPP-4) | UniProt   NCBI |
SLC9A1 | Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1) | UniProt   NCBI |
LMBR1 | Limb region 1 protein homolog (Differentiation-related gene 14 protein) | UniProt   NCBI |
LPAR1 | Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2) | UniProt   NCBI |
TESC | Calcineurin B homologous protein 3 (Tescalcin) (TSC) | UniProt   NCBI |
IPPK | Inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) (IPK1 homolog) (Inositol-1,3,4,5,6-pentakisphosphate 2-kinase) (Ins(1,3,4,5,6)P5 2-kinase) (InsP5 2-kinase) | UniProt   NCBI |
MFSD8 | Major facilitator superfamily domain-containing protein 8 (Ceroid-lipofuscinosis neuronal protein 7) | UniProt   NCBI |
CERS4 | Ceramide synthase 4 (CerS4) (LAG1 longevity assurance homolog 4) | UniProt   NCBI |
SC5D | Lathosterol oxidase (EC 1.14.19.20) (C-5 sterol desaturase) (Delta(7)-sterol 5-desaturase) (Delta(7)-sterol C5(6)-desaturase) (Lathosterol 5-desaturase) (Sterol-C5-desaturase) | UniProt   NCBI |
MAS1 | Proto-oncogene Mas | UniProt   NCBI |
EXTL2 | Exostosin-like 2 (EC 2.4.1.223) (Alpha-1,4-N-acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2) (Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) [Cleaved into: Processed exostosin-like 2] | UniProt   NCBI |
SYP | Synaptophysin (Major synaptic vesicle protein p38) | UniProt   NCBI |
GPR50 | Melatonin-related receptor (G protein-coupled receptor 50) (H9) | UniProt   NCBI |
GALNT7 | N-acetylgalactosaminyltransferase 7 (EC 2.4.1.41) (Polypeptide GalNAc transferase 7) (GalNAc-T7) (pp-GaNTase 7) (Protein-UDP acetylgalactosaminyltransferase 7) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7) | UniProt   NCBI |
TMEM87B | Transmembrane protein 87B | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  WP:WP247 | 0.00562581664918 | 0.111111111111 | GPR50 LPAR1 | Small Ligand GPCRs |
Edges
Protein 1 | Protein 2 | Score | Precision | Evidence |
---|---|---|---|---|
 IPPK |  LPAR1 | 0.988 | 0.902           | bioplex (IPPK)     bioplex_WMM     |
 TESC |  IPPK | 0.432 | 0.578           | bioplex (IPPK)     bioplex_WMM     |
 TESC |  LPAR1 | 0.148 | 0.41           | bioplex (LPAR1)     bioplex_WMM     |
 SLC9A1 |  LPAR1 | 0.122 | 0.394           | bioplex (LPAR1)     bioplex_WMM     |
 CERS4 |  LPAR1 | 0.102 | 0.364           | bioplex (LPAR1)     bioplex_WMM     |
 ENPP4 |  LPAR1 | 0.093 | 0.355           | bioplex (LPAR1)     bioplex_WMM     |
 SELENOT |  IPPK | 0.079 | 0.353           | bioplex (IPPK)     bioplex_WMM     |
 IPPK |  GPR137 | 0.07 | 0.348           | bioplex (IPPK)     bioplex_WMM     |
 IPPK |  SLC9A1 | 0.037 | 0.264           | bioplex (IPPK)     bioplex_WMM     |
 LMBR1 |  LPAR1 | 0.032 | 0.245           | bioplex (LPAR1)     bioplex_WMM     |
 MFSD8 |  LPAR1 | 0.031 | 0.24           | bioplex (LPAR1)     bioplex_WMM     |
 GPR137 |  LPAR1 | 0.029 | 0.232           | bioplex (LPAR1)     bioplex_WMM     |
 GALNT7 |  SLC9A1 | 0.027 | 0.23           | bioplex (GALNT7)     bioplex_WMM     |
 SC5D |  LPAR1 | 0.027 | 0.231           | bioplex (LPAR1)     bioplex_WMM     |
 LPAR1 |  EXTL2 | 0.027 | 0.223           | bioplex_WMM     bioplex ()     |
 IPPK |  ENPP4 | 0.026 | 0.218           | bioplex (IPPK)     bioplex_WMM     |
 IPPK |  TMEM87B | 0.026 | 0.215           | bioplex (IPPK)     bioplex_WMM     |
 IPPK |  SC5D | 0.025 | 0.216           | bioplex (IPPK)     bioplex_WMM     |
 IPPK |  CERS4 | 0.025 | 0.212           | bioplex (IPPK)     bioplex_WMM     |
 SYP |  LPAR1 | 0.023 | 0.21           | bioplex (LPAR1)     bioplex_WMM     |
 IPPK |  GPR50 | 0.022 | 0.205           | bioplex (IPPK)     bioplex_WMM     |
 HVCN1 |  LPAR1 | 0.022 | 0.205           | bioplex (LPAR1)     bioplex_WMM     |
 GPR50 |  MAS1 | 0.02 | 0.188           | bioplex (MAS1)     bioplex_WMM     |
 IPPK |  SYP | 0.017 | 0.168           | bioplex (IPPK)     bioplex_WMM     |
 TESC |  CERS4 | 0.011 | 0.141           | bioplex_WMM     WMM_only     |
 GPR50 |  LPAR1 | 0.01 | 0.14           | bioplex (LPAR1)     bioplex_WMM     |
 IPPK |  LMBR1 | 0.01 | 0.129           | bioplex (IPPK)     bioplex_WMM     |
 GPR137 |  CERS4 | 0.01 | 0.128           | bioplex_WMM     WMM_only     |
 TESC |  GPR137 | 0.01 | 0.128           | bioplex_WMM     WMM_only     |
 TESC |  TMEM87B | 0.009 | 0.114           | bioplex_WMM     WMM_only     |
 TMEM87B |  CERS4 | 0.009 | 0.114           | bioplex_WMM     WMM_only     |
 TESC |  SYP | 0.009 | 0.108           | bioplex_WMM     WMM_only     |
 ENPP4 |  CERS4 | 0.009 | 0.108           | bioplex_WMM     WMM_only     |
 SYP |  CERS4 | 0.009 | 0.108           | bioplex_WMM     WMM_only     |
 TESC |  ENPP4 | 0.009 | 0.108           | bioplex_WMM     WMM_only     |
 GPR137 |  TMEM87B | 0.009 | 0.105           | bioplex_WMM     WMM_only     |
 SLC9A1 |  CERS4 | 0.009 | 0.09           | bioplex_WMM     youn_WMM     WMM_only     |
 GPR137 |  ENPP4 | 0.009 | 0.094           | bioplex_WMM     WMM_only     |
 GPR137 |  SYP | 0.009 | 0.094           | bioplex_WMM     WMM_only     |
 TESC |  SELENOT | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 SELENOT |  CERS4 | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 MFSD8 |  SC5D | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 TESC |  SC5D | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 CERS4 |  SC5D | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 TESC |  GPR50 | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 GPR50 |  CERS4 | 0.009 | 0.098           | bioplex_WMM     WMM_only     |
 TESC |  SLC9A1 | 0.009 | 0.092           | bioplex_WMM     WMM_only     |
 TMEM87B |  ENPP4 | 0.008 | 0.089           | bioplex_WMM     WMM_only     |
 MFSD8 |  LMBR1 | 0.008 | 0.089           | bioplex_WMM     WMM_only     |
 GPR137 |  LMBR1 | 0.008 | 0.084           | bioplex_WMM     WMM_only     |
 SELENOT |  GPR137 | 0.008 | 0.083           | bioplex_WMM     WMM_only     |
 HVCN1 |  CERS4 | 0.008 | 0.085           | bioplex_WMM     WMM_only     |
 TESC |  HVCN1 | 0.008 | 0.085           | bioplex_WMM     WMM_only     |
 GPR137 |  SC5D | 0.008 | 0.085           | bioplex_WMM     WMM_only     |
 TESC |  MFSD8 | 0.008 | 0.085           | bioplex_WMM     WMM_only     |
 MFSD8 |  CERS4 | 0.008 | 0.085           | bioplex_WMM     WMM_only     |
 GPR137 |  GPR50 | 0.008 | 0.083           | bioplex_WMM     WMM_only     |
 MFSD8 |  TMEM87B | 0.008 | 0.083           | bioplex_WMM     WMM_only     |
 GPR137 |  SLC9A1 | 0.008 | 0.081           | bioplex_WMM     WMM_only     |
 TMEM87B |  SYP | 0.008 | 0.076           | bioplex_WMM     WMM_only     |
 GPR137 |  HVCN1 | 0.008 | 0.067           | bioplex_WMM     WMM_only     |
 SELENOT |  TMEM87B | 0.008 | 0.067           | bioplex_WMM     WMM_only     |
 TMEM87B |  SC5D | 0.008 | 0.059           | bioplex_WMM     WMM_only     |
 SYP |  ENPP4 | 0.008 | 0.047           | bioplex_WMM     WMM_only     |
 TMEM87B |  SLC9A1 | 0.008 | 0.043           | bioplex_WMM     WMM_only     |
 LMBR1 |  CERS4 | 0.008 | 0.045           | bioplex_WMM     WMM_only     |
 TESC |  LMBR1 | 0.008 | 0.045           | bioplex_WMM     WMM_only     |
 TMEM87B |  HVCN1 | 0.008 | 0.04           | bioplex_WMM     WMM_only     |
 GPR137 |  MFSD8 | 0.008 | 0.034           | bioplex_WMM     WMM_only     |
 HVCN1 |  ENPP4 | 0.008 | 0.026           | bioplex_WMM     WMM_only     |
 SYP |  HVCN1 | 0.008 | 0.026           | bioplex_WMM     WMM_only     |
 SELENOT |  ENPP4 | 0.008 | 0.025           | bioplex_WMM     WMM_only     |
 SLC9A1 |  HVCN1 | 0.008 | 0.026           | bioplex_WMM     gupta_WMM     WMM_only     |
 TMEM87B |  EXTL2 | 0.008 | 0.013           | bioplex_WMM     WMM_only     |
 GPR50 |  TMEM87B | 0.008 | 0.017           | bioplex_WMM     WMM_only     |
 ENPP4 |  SC5D | 0.008 | 0.012           | bioplex_WMM     WMM_only     |
 CERS4 |  EXTL2 | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 SELENOT |  HVCN1 | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 TESC |  EXTL2 | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 HVCN1 |  SC5D | 0.007 | 0.01           | bioplex_WMM     WMM_only     |
 SLC9A1 |  ENPP4 | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 GPR50 |  HVCN1 | 0.007 | 0.004           | bioplex_WMM     WMM_only     |
 SELENOT |  SYP | 0.007 | 0.008           | bioplex_WMM     WMM_only     |
 SYP |  SC5D | 0.007 | 0.005           | bioplex_WMM     WMM_only     |
 TMEM87B |  LMBR1 | 0.007 | 0.009           | bioplex_WMM     WMM_only     |
 GPR137 |  EXTL2 | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 GPR50 |  ENPP4 | 0.007 | 0.014           | bioplex_WMM     WMM_only     |
 GPR50 |  SYP | 0.007 | 0.014           | bioplex_WMM     WMM_only     |
 ENPP4 |  EXTL2 | 0.007 | 0.008           | bioplex_WMM     WMM_only     |
 SLC9A1 |  SYP | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 SC5D |  EXTL2 | 0.007 | 0.007           | bioplex_WMM     WMM_only     |
 MFSD8 |  HVCN1 | 0.007 | 0.017           | bioplex_WMM     WMM_only     |
 MFSD8 |  GPR50 | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 SLC9A1 |  EXTL2 | 0.007 | 0.005           | bioplex_WMM     WMM_only     |
 IPPK |  EXTL2 | 0.007 | 0.003           | bioplex (IPPK)     bioplex_WMM     |
 SELENOT |  SC5D | 0.007 | 0.005           | bioplex_WMM     WMM_only     |
 SELENOT |  EXTL2 | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 MFSD8 |  ENPP4 | 0.007 | 0.005           | bioplex_WMM     WMM_only     |
 HVCN1 |  LMBR1 | 0.007 | 0.001           | bioplex_WMM     WMM_only     |
 SELENOT |  SLC9A1 | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 MFSD8 |  EXTL2 | 0.007 | 0.005           | bioplex_WMM     WMM_only     |
 SYP |  EXTL2 | 0.007 | 0.001           | bioplex_WMM     WMM_only     |
 MFSD8 |  SYP | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 SLC9A1 |  SC5D | 0.007 | 0.004           | bioplex_WMM     WMM_only     |
 SELENOT |  GPR50 | 0.007 | 0.0           | bioplex_WMM     WMM_only     |
 GPR50 |  LMBR1 | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 GPR50 |  SC5D | 0.007 | 0.002           | bioplex_WMM     WMM_only     |
 GPR50 |  SLC9A1 | 0.007 | 0.001           | bioplex_WMM     WMM_only     |
 SELENOT |  MFSD8 | 0.007 | 0.003           | bioplex_WMM     WMM_only     |
 GPR50 |  EXTL2 | 0.007 | 0.004           | bioplex_WMM     WMM_only     |
 MFSD8 |  SLC9A1 | 0.007 | 0.007           | bioplex_WMM     WMM_only     |
 LMBR1 |  SC5D | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 SYP |  LMBR1 | 0.007 | 0.006           | bioplex_WMM     WMM_only     |
 ENPP4 |  LMBR1 | 0.007 | 0.002           | bioplex_WMM     WMM_only     |
 GALNT7 |  TMEM87B | 0.007 | 0.007           | bioplex_WMM     WMM_only     |
 SLC9A1 |  LMBR1 | 0.007 | 0.005           | bioplex_WMM     WMM_only     |
 LMBR1 |  EXTL2 | 0.006 | 0.007           | bioplex_WMM     WMM_only     |
 SELENOT |  LMBR1 | 0.006 | 0.004           | bioplex_WMM     WMM_only     |
 GALNT7 |  EXTL2 | 0.006 | 0.002           | bioplex_WMM     WMM_only     |
 GALNT7 |  LMBR1 | 0.005 | 0.009           | bioplex_WMM     WMM_only     |
 SELENOT |  LPAR1 | 0.005 | 0.006           | bioplex (LPAR1)     bioplex_WMM     |
 IPPK |  MFSD8 | 0.005 | 0.008           | bioplex (IPPK)     bioplex_WMM     |
 TMEM87B |  LPAR1 | 0.0 | 0.007           | bioplex (LPAR1)     bioplex_WMM     |
Images
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Complex HuMAP2_05923 has an average edge precision of 0.095 which is ranked 6945 out of all 6965 complexes.
Related Complexes
Genename | Complexes |
---|---|
GPR137 | HuMAP2_01056 HuMAP2_05923 |
SELENOT | HuMAP2_01056 HuMAP2_03515 HuMAP2_05923 |
HVCN1 | HuMAP2_05923 |
ENPP4 | HuMAP2_05923 |
SLC9A1 | HuMAP2_05516 HuMAP2_05923 |
LMBR1 | HuMAP2_05923 |
LPAR1 | HuMAP2_05923 HuMAP2_06586 |
TESC | HuMAP2_01056 HuMAP2_05923 |
IPPK | HuMAP2_01056 HuMAP2_05923 HuMAP2_06586 |
MFSD8 | HuMAP2_02035 HuMAP2_05460 HuMAP2_05923 |
CERS4 | HuMAP2_05923 |
SC5D | HuMAP2_05923 |
MAS1 | HuMAP2_02143 HuMAP2_05923 |
EXTL2 | HuMAP2_05923 |
SYP | HuMAP2_05645 HuMAP2_05923 |
GPR50 | HuMAP2_02143 HuMAP2_05923 |
GALNT7 | HuMAP2_03643 HuMAP2_05516 HuMAP2_05923 |
TMEM87B | HuMAP2_04083 HuMAP2_05923 |