hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05924
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NDUFA8 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (Complex I-19kD) (CI-19kD) (Complex I-PGIV) (CI-PGIV) (NADH-ubiquinone oxidoreductase 19 kDa subunit) | UniProt NCBI |
| NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (Complex I-MWFE) (CI-MWFE) (NADH-ubiquinone oxidoreductase MWFE subunit) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2919 | 7.54165558069e-05 | 1.0 | NDUFA1 NDUFA8 | Respiratory chain complex I (gamma subunit) mitochondrial |
| WP:WP4324 | 0.000513417075107 | 1.0 | NDUFA1 NDUFA8 | Mitochondrial complex I assembly model OXPHOS system |
| KEGG:00190 | 0.00100713074717 | 1.0 | NDUFA1 NDUFA8 | Oxidative phosphorylation |
| KEGG:05012 | 0.00114894316007 | 1.0 | NDUFA1 NDUFA8 | Parkinson disease |
| KEGG:04723 | 0.0012614301666 | 1.0 | NDUFA1 NDUFA8 | Retrograde endocannabinoid signaling |
| KEGG:04932 | 0.00128068864242 | 1.0 | NDUFA1 NDUFA8 | Non-alcoholic fatty liver disease (NAFLD) |
| CORUM:178 | 0.00130722030065 | 1.0 | NDUFA1 NDUFA8 | Respiratory chain complex I (holoenzyme), mitochondrial |
| WP:WP111 | 0.00159390293709 | 1.0 | NDUFA1 NDUFA8 | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:05010 | 0.00171881896746 | 1.0 | NDUFA1 NDUFA8 | Alzheimer disease |
| REAC:R-HSA-6799198 | 0.00222227451111 | 1.0 | NDUFA1 NDUFA8 | Complex I biogenesis |
| KEGG:05016 | 0.00224682217969 | 1.0 | NDUFA1 NDUFA8 | Huntington disease |
| KEGG:04714 | 0.00317122901933 | 1.0 | NDUFA1 NDUFA8 | Thermogenesis |
| WP:WP4396 | 0.00347096768628 | 1.0 | NDUFA1 NDUFA8 | Nonalcoholic fatty liver disease |
| REAC:R-HSA-611105 | 0.00732546145404 | 1.0 | NDUFA1 NDUFA8 | Respiratory electron transport |
| REAC:R-HSA-163200 | 0.011178409494 | 1.0 | NDUFA1 NDUFA8 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| REAC:R-HSA-1428517 | 0.0226752444459 | 1.0 | NDUFA1 NDUFA8 | The citric acid (TCA) cycle and respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NDUFA8 | NDUFA1 | 0.549 | 0.643 | bioplex (NDUFA8) bioplex_WMM |
Images
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Complex HuMAP2_05924 has an average edge precision of 0.643 which is ranked 1686 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NDUFA8 | HuMAP2_00273 HuMAP2_01373 HuMAP2_01573 HuMAP2_01600 HuMAP2_02247 HuMAP2_04424 HuMAP2_05114 HuMAP2_05273 HuMAP2_05924 |
| NDUFA1 | HuMAP2_01573 HuMAP2_04424 HuMAP2_05273 HuMAP2_05924 |