hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05933
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EXO1 | Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI) | UniProt NCBI |
| DHX35 | Probable ATP-dependent RNA helicase DHX35 (EC 3.6.4.13) (DEAH box protein 35) | UniProt NCBI |
| GPATCH1 | G patch domain-containing protein 1 (Evolutionarily conserved G-patch domain-containing protein) | UniProt NCBI |
| SIPA1L3 | Signal-induced proliferation-associated 1-like protein 3 (SIPA1-like protein 3) (SPA-1-like protein 3) | UniProt NCBI |
| DCAF13 | DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1) | UniProt NCBI |
| RIMS4 | Regulating synaptic membrane exocytosis protein 4 (RIM4 gamma) (Rab3-interacting molecule 4) (RIM 4) | UniProt NCBI |
| USB1 | U6 snRNA phosphodiesterase (hUsb1) (EC 3.1.4.-) | UniProt NCBI |
| SH2B2 | SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS) | UniProt NCBI |
| ZBTB49 | Zinc finger and BTB domain-containing protein 49 (Zinc finger protein 509) | UniProt NCBI |
| WDR83 | WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1) | UniProt NCBI |
| ZNF140 | Zinc finger protein 140 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1181 | 0.00120153329648 | 0.3 | DHX35 GPATCH1 WDR83 | C complex spliceosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GPATCH1 | WDR83 | 0.999 | 0.949 | bioplex (WDR83) bioplex_WMM youn_WMM gupta_WMM |
| WDR83 | DHX35 | 0.984 | 0.899 | bioplex (WDR83) bioplex_WMM youn_WMM gupta_WMM |
| DCAF13 | WDR83 | 0.935 | 0.85 | bioplex (WDR83) bioplex_WMM youn_WMM |
| WDR83 | SH2B2 | 0.817 | 0.773 | bioplex (WDR83) bioplex_WMM youn_WMM |
| WDR83 | SIPA1L3 | 0.692 | 0.717 | bioplex (WDR83) bioplex_WMM youn_WMM gupta_WMM |
| WDR83 | EXO1 | 0.45 | 0.594 | bioplex (WDR83) bioplex_WMM |
| WDR83 | ZNF140 | 0.4 | 0.561 | bioplex (WDR83) bioplex_WMM |
| GPATCH1 | USB1 | 0.38 | 0.548 | bioplex (USB1) bioplex_WMM |
| WDR83 | RIMS4 | 0.327 | 0.516 | bioplex (WDR83) bioplex_WMM |
| WDR83 | ZBTB49 | 0.317 | 0.509 | bioplex (WDR83) bioplex_WMM |
| USB1 | DHX35 | 0.094 | 0.356 | bioplex (USB1) bioplex_WMM |
| GPATCH1 | DHX35 | 0.033 | 0.248 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| WDR83 | USB1 | 0.015 | 0.14 | bioplex (USB1) bioplex_WMM |
| SIPA1L3 | EXO1 | 0.01 | 0.1 | bioplex_WMM WMM_only boldt_WMM |
| RIMS4 | ZNF140 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| ZBTB49 | ZNF140 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| SH2B2 | ZNF140 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| SH2B2 | ZBTB49 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| EXO1 | ZNF140 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| EXO1 | ZBTB49 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| SH2B2 | RIMS4 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| RIMS4 | ZBTB49 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| EXO1 | RIMS4 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| SH2B2 | EXO1 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| SIPA1L3 | ZNF140 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| SIPA1L3 | RIMS4 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| SH2B2 | SIPA1L3 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| SIPA1L3 | ZBTB49 | 0.009 | 0.104 | bioplex_WMM WMM_only |
| DCAF13 | ZBTB49 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| DCAF13 | RIMS4 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| DCAF13 | ZNF140 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| DCAF13 | SH2B2 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| DCAF13 | EXO1 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| DCAF13 | SIPA1L3 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| SIPA1L3 | DHX35 | 0.009 | 0.097 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GPATCH1 | SIPA1L3 | 0.008 | 0.092 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GPATCH1 | SH2B2 | 0.008 | 0.082 | bioplex_WMM youn_WMM WMM_only |
| GPATCH1 | RIMS4 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| GPATCH1 | EXO1 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| GPATCH1 | ZNF140 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| GPATCH1 | ZBTB49 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| SH2B2 | DHX35 | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only |
| DHX35 | EXO1 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| DHX35 | ZNF140 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| DHX35 | RIMS4 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| DHX35 | ZBTB49 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| GPATCH1 | DCAF13 | 0.008 | 0.032 | bioplex_WMM youn_WMM WMM_only |
| DCAF13 | DHX35 | 0.008 | 0.023 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05933 has an average edge precision of 0.228 which is ranked 5737 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| EXO1 | HuMAP2_04045 HuMAP2_04789 HuMAP2_05933 |
| DHX35 | HuMAP2_03672 HuMAP2_04045 HuMAP2_05933 |
| GPATCH1 | HuMAP2_01551 HuMAP2_03672 HuMAP2_04045 HuMAP2_05933 |
| SIPA1L3 | HuMAP2_02173 HuMAP2_03772 HuMAP2_04789 HuMAP2_05933 |
| DCAF13 | HuMAP2_01551 HuMAP2_04444 HuMAP2_04789 HuMAP2_05419 HuMAP2_05933 |
| RIMS4 | HuMAP2_04045 HuMAP2_04789 HuMAP2_05933 |
| USB1 | HuMAP2_03672 HuMAP2_04045 HuMAP2_05933 |
| SH2B2 | HuMAP2_01551 HuMAP2_04045 HuMAP2_04789 HuMAP2_05933 |
| ZBTB49 | HuMAP2_04045 HuMAP2_04789 HuMAP2_05933 |
| WDR83 | HuMAP2_01551 HuMAP2_04045 HuMAP2_04789 HuMAP2_05933 |
| ZNF140 | HuMAP2_04045 HuMAP2_04789 HuMAP2_05933 |