hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05937
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RTCB | tRNA-splicing ligase RtcB homolog (EC 6.5.1.3) | UniProt NCBI |
| HNRNPM | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) | UniProt NCBI |
| DDX1 | ATP-dependent RNA helicase DDX1 (EC 3.6.4.13) (DEAD box protein 1) (DEAD box protein retinoblastoma) (DBP-RB) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6301 | 3.35555483123e-05 | 0.666666666667 | DDX1 RTCB | tRNA Splicing Ligase Complex |
| CORUM:1332 | 0.000637127241024 | 0.666666666667 | DDX1 HNRNPM | Large Drosha complex |
| WP:WP411 | 0.00739285752446 | 0.666666666667 | DDX1 HNRNPM | mRNA Processing |
| REAC:R-HSA-6784531 | 0.00955880978777 | 0.666666666667 | DDX1 RTCB | tRNA processing in the nucleus |
| REAC:R-HSA-8953854 | 0.0206735000409 | 1.0 | DDX1 RTCB HNRNPM | Metabolism of RNA |
| REAC:R-HSA-72306 | 0.0343335993912 | 0.666666666667 | DDX1 RTCB | tRNA processing |
| GO:0072669 | 0.0378589948753 | 0.666666666667 | DDX1 RTCB | tRNA-splicing ligase complex |
| WP:WP2942 | 0.0499785733994 | 0.333333333333 | DDX1 | DDX1 as a regulatory component of the Drosha microprocessor |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX1 | RTCB | 1.0 | 0.949 | hein_WMM youn (DDX1) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| RTCB | HNRNPM | 0.723 | 0.733 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| DDX1 | HNRNPM | 0.579 | 0.661 | hein_WMM youn (DDX1) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_05937 has an average edge precision of 0.781 which is ranked 997 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RTCB | HuMAP2_00096 HuMAP2_01139 HuMAP2_01163 HuMAP2_01397 HuMAP2_04108 HuMAP2_05216 HuMAP2_05937 |
| HNRNPM | HuMAP2_00096 HuMAP2_03821 HuMAP2_04108 HuMAP2_05216 HuMAP2_05937 |
| DDX1 | HuMAP2_00096 HuMAP2_01139 HuMAP2_01163 HuMAP2_02412 HuMAP2_05937 |