hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05939
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EPN2 | Epsin-2 (EPS-15-interacting protein 2) | UniProt NCBI |
| PHGDH | D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37) | UniProt NCBI |
| EPN1 | Epsin-1 (EH domain-binding mitotic phosphoprotein) (EPS-15-interacting protein 1) | UniProt NCBI |
| EPN3 | Epsin-3 (EPS-15-interacting protein 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.000539397470166 | 0.75 | EPN2 EPN1 EPN3 | Endocytosis |
| REAC:R-HSA-8856825 | 0.0390714342086 | 0.5 | EPN2 EPN1 | Cargo recognition for clathrin-mediated endocytosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EPN2 | EPN3 | 1.0 | 0.949 | bioplex (EPN3) bioplex_WMM youn_WMM |
| EPN3 | EPN1 | 0.994 | 0.921 | bioplex (EPN3) bioplex_WMM youn_WMM gupta_WMM |
| EPN3 | PHGDH | 0.86 | 0.796 | bioplex (EPN3) bioplex_WMM youn_WMM gupta_WMM |
| EPN2 | EPN1 | 0.01 | 0.129 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| EPN2 | PHGDH | 0.01 | 0.129 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PHGDH | EPN1 | 0.0 | 0.001 | hein_WMM bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_05939 has an average edge precision of 0.487 which is ranked 2570 out of all 6965 complexes.
Related Complexes