hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05944
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ACTA2 | Actin, aortic smooth muscle (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form] | UniProt NCBI |
| ZMAT3 | Zinc finger matrin-type protein 3 (Zinc finger protein WIG-1) (p53-activated gene 608 protein) | UniProt NCBI |
| SPICE1 | Spindle and centriole-associated protein 1 (Coiled-coil domain-containing protein 52) (Spindle and centriole-associated protein) | UniProt NCBI |
| N4BP3 | NEDD4-binding protein 3 (N4BP3) | UniProt NCBI |
| CEP295 | Centrosomal protein of 295 kDa | UniProt NCBI |
| CEP72 | Centrosomal protein of 72 kDa (Cep72) | UniProt NCBI |
| DCAF17 | DDB1- and CUL4-associated factor 17 | UniProt NCBI |
| SPATA24 | Spermatogenesis-associated protein 24 (Testis protein T6441 homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0007099 | 0.0301968453576 | 0.375 | CEP295 CEP72 SPICE1 | centriole replication |
| GO:0098534 | 0.0360121609904 | 0.375 | CEP295 CEP72 SPICE1 | centriole assembly |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZMAT3 | DCAF17 | 0.999 | 0.949 | bioplex (ZMAT3) bioplex_WMM |
| SPATA24 | DCAF17 | 0.137 | 0.407 | bioplex (SPATA24) bioplex_WMM |
| SPATA24 | CEP72 | 0.1 | 0.36 | bioplex (CEP72) bioplex_WMM youn_WMM gupta_WMM |
| CEP72 | CEP295 | 0.039 | 0.266 | hein_WMM youn_WMM hein (CEP72) gupta_WMM |
| SPICE1 | CEP295 | 0.032 | 0.246 | hein_WMM bioplex (SPICE1) bioplex_WMM youn_WMM gupta_WMM gupta (SPICE1) |
| CEP72 | N4BP3 | 0.021 | 0.195 | hein_WMM hein (CEP72) gupta_WMM |
| ZMAT3 | ACTA2 | 0.021 | 0.191 | bioplex (ZMAT3) bioplex_WMM |
| CEP72 | ACTA2 | 0.007 | 0.003 | gupta_WMM WMM_only |
| SPATA24 | SPICE1 | 0.007 | 0.006 | gupta_WMM WMM_only |
| ACTA2 | N4BP3 | 0.007 | 0.001 | gupta_WMM WMM_only |
| SPATA24 | ACTA2 | 0.007 | 0.002 | gupta_WMM WMM_only |
| ACTA2 | CEP295 | 0.007 | 0.002 | hein_WMM gupta_WMM WMM_only boldt_WMM |
| DCAF17 | ACTA2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| N4BP3 | CEP295 | 0.006 | 0.003 | hein_WMM gupta_WMM WMM_only |
| SPICE1 | ACTA2 | 0.005 | 0.013 | gupta_WMM gupta (SPICE1) |
| SPICE1 | N4BP3 | 0.003 | 0.013 | hein_WMM gupta (SPICE1) |
| SPICE1 | CEP72 | 0.0 | 0.008 | hein_WMM youn_WMM gupta_WMM gupta (SPICE1) |
Images
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Complex HuMAP2_05944 has an average edge precision of 0.157 which is ranked 6656 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ACTA2 | HuMAP2_01827 HuMAP2_02950 HuMAP2_05944 |
| ZMAT3 | HuMAP2_01827 HuMAP2_02950 HuMAP2_03377 HuMAP2_05908 HuMAP2_05944 |
| SPICE1 | HuMAP2_01687 HuMAP2_05143 HuMAP2_05944 HuMAP2_06047 HuMAP2_06578 |
| N4BP3 | HuMAP2_05944 HuMAP2_06503 |
| CEP295 | HuMAP2_05944 HuMAP2_06377 HuMAP2_06578 |
| CEP72 | HuMAP2_01789 HuMAP2_02050 HuMAP2_03013 HuMAP2_04000 HuMAP2_05944 HuMAP2_06503 |
| DCAF17 | HuMAP2_01827 HuMAP2_02950 HuMAP2_03377 HuMAP2_05908 HuMAP2_05944 |
| SPATA24 | HuMAP2_01006 HuMAP2_01827 HuMAP2_05908 HuMAP2_05944 |