hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05947
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NAE1 | NEDD8-activating enzyme E1 regulatory subunit (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Amyloid protein-binding protein 1) (Proto-oncogene protein 1) | UniProt NCBI |
| UBA3 | NEDD8-activating enzyme E1 catalytic subunit (EC 6.2.1.-) (NEDD8-activating enzyme E1C) (Ubiquitin-activating enzyme E1C) (Ubiquitin-like modifier-activating enzyme 3) (Ubiquitin-activating enzyme 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2162 | 1.67592346237e-06 | 1.0 | UBA3 NAE1 | APPBP1-UBA3 complex |
| GO:0019781 | 0.000450823411379 | 1.0 | UBA3 NAE1 | NEDD8 activating enzyme activity |
| GO:0008641 | 0.0162296428096 | 1.0 | UBA3 NAE1 | ubiquitin-like modifier activating enzyme activity |
| REAC:R-HSA-8951664 | 0.0411120784555 | 1.0 | UBA3 NAE1 | Neddylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UBA3 | NAE1 | 0.966 | 0.875 | bioplex_WMM youn_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_05947 has an average edge precision of 0.875 which is ranked 676 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NAE1 | HuMAP2_00413 HuMAP2_03398 HuMAP2_05548 HuMAP2_05947 |
| UBA3 | HuMAP2_00413 HuMAP2_03398 HuMAP2_05548 HuMAP2_05947 |