hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
RAB4B	Ras-related protein Rab-4B	UniProt NCBI
ECI1	Enoyl-CoA delta isomerase 1, mitochondrial (EC 5.3.3.8) (3,2-trans-enoyl-CoA isomerase) (Delta(3),Delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Dodecenoyl-CoA isomerase)	UniProt NCBI
RAP1B	Ras-related protein Rap-1b (GTP-binding protein smg p21B)	UniProt NCBI
FAM71F2	Protein FAM71F2 (Protein FAM137B)	UniProt NCBI
RAB7A	Ras-related protein Rab-7a	UniProt NCBI
RAB2A	Ras-related protein Rab-2A	UniProt NCBI
RAB2B	Ras-related protein Rab-2B	UniProt NCBI
RAB14	Ras-related protein Rab-14	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-8873719	1.04263792074e-08	0.625	RAB7A RAB2B RAB4B RAB2A RAB14	RAB geranylgeranylation
GO:0032482	5.90691289327e-06	0.625	RAB7A RAB2B RAB4B RAB2A RAB14	Rab protein signal transduction
GO:0003924	2.6022146593e-05	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	GTPase activity
GO:0007265	7.93376992765e-05	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	Ras protein signal transduction
GO:0007264	0.000469384667037	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	small GTPase mediated signal transduction
GO:0019003	0.0010043755339	0.5	RAB7A RAB14 RAB2A RAP1B	GDP binding
GO:0017111	0.00427281124245	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	nucleoside-triphosphatase activity
GO:0016462	0.00637283867876	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	pyrophosphatase activity
GO:0016817	0.0064969623439	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	hydrolase activity, acting on acid anhydrides
GO:0016818	0.0064969623439	0.75	RAB2B RAB2A RAP1B RAB14 RAB7A RAB4B	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
REAC:R-HSA-6798695	0.00782589647258	0.5	RAB7A RAB14 RAB4B RAP1B	Neutrophil degranulation
REAC:R-HSA-597592	0.034214843382	0.625	RAB7A RAB2B RAB4B RAB2A RAB14	Post-translational protein modification

Protein 1	Protein 2	Score	Precision	Evidence
RAB2B	RAB2A	0.618	0.674	bioplex (RAB2B) bioplex_WMM youn_WMM gupta_WMM
RAB7A	RAB2A	0.135	0.407	hein_WMM bioplex_WMM Guru boldt hein (RAB2A) gupta_WMM fraction boldt_WMM treiber_WMM
RAP1B	RAB7A	0.11	0.379	hein_WMM bioplex_WMM Guru boldt gupta_WMM fraction boldt_WMM
RAB14	RAB7A	0.065	0.347	hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM treiber_WMM
RAB2B	FAM71F2	0.058	0.323	bioplex (FAM71F2) bioplex_WMM
RAB2B	RAB14	0.046	0.293	bioplex (RAB2B) bioplex_WMM youn_WMM gupta_WMM
RAB14	RAB4B	0.025	0.217	hein_WMM bioplex_WMM hein (RAB4B)
RAB14	ECI1	0.021	0.186	bioplex_WMM gupta_WMM fraction treiber_WMM
RAB14	RAB2A	0.013	0.149	bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM
FAM71F2	RAB2A	0.012	0.147	bioplex (FAM71F2) bioplex_WMM
RAB14	RAP1B	0.01	0.103	hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM
RAB2B	RAB7A	0.009	0.097	bioplex (RAB2B) bioplex_WMM gupta_WMM
RAB2B	RAB4B	0.008	0.087	bioplex_WMM WMM_only
RAB2A	RAB4B	0.008	0.065	bioplex_WMM gupta_WMM WMM_only
RAB7A	RAB4B	0.008	0.025	bioplex_WMM gupta_WMM WMM_only
RAB7A	ECI1	0.007	0.006	bioplex_WMM gupta_WMM WMM_only treiber_WMM
RAP1B	ECI1	0.007	0.006	bioplex_WMM WMM_only
FAM71F2	ECI1	0.007	0.006	bioplex (FAM71F2)
RAB2B	RAP1B	0.007	0.002	bioplex (RAB2B) bioplex_WMM
RAP1B	RAB2A	0.006	0.009	bioplex_WMM Guru boldt gupta_WMM fraction boldt_WMM
RAB2A	ECI1	0.0	0.009	bioplex_WMM Guru gupta_WMM fraction treiber_WMM

Click to enlarge

Complex HuMAP2_05948 has an average edge precision of 0.168 which is ranked 6543 out of all 6965 complexes.

Genename	Complexes
RAB4B	HuMAP2_00952 HuMAP2_02330 HuMAP2_05948
ECI1	HuMAP2_00363 HuMAP2_00952 HuMAP2_04952 HuMAP2_05948
RAP1B	HuMAP2_00248 HuMAP2_02250 HuMAP2_04766 HuMAP2_05570 HuMAP2_05778 HuMAP2_05948 HuMAP2_06607
FAM71F2	HuMAP2_00248 HuMAP2_00952 HuMAP2_02330 HuMAP2_05948 HuMAP2_07007
RAB7A	HuMAP2_00248 HuMAP2_02250 HuMAP2_05110 HuMAP2_05570 HuMAP2_05778 HuMAP2_05948
RAB2A	HuMAP2_00248 HuMAP2_00952 HuMAP2_02250 HuMAP2_02330 HuMAP2_04581 HuMAP2_05778 HuMAP2_05948 HuMAP2_07007
RAB2B	HuMAP2_00248 HuMAP2_00952 HuMAP2_02330 HuMAP2_04581 HuMAP2_05948 HuMAP2_07007
RAB14	HuMAP2_00248 HuMAP2_00952 HuMAP2_02330 HuMAP2_05948