hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05963
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CLDND1 | Claudin domain-containing protein 1 (Membrane protein GENX-3745) | UniProt NCBI |
| ZDHHC8 | Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378) | UniProt NCBI |
| GOLGA7 | Golgin subfamily A member 7 (Golgi complex-associated protein of 16 kDa) | UniProt NCBI |
| MAN1A2 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) | UniProt NCBI |
| MAN1A1 | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Man9-mannosidase) (Mannosidase alpha class 1A member 1) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-964827 | 4.04876825444e-05 | 0.4 | MAN1A1 MAN1A2 | Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 |
| REAC:R-HSA-964739 | 0.000134922692372 | 0.4 | MAN1A1 MAN1A2 | N-glycan trimming and elongation in the cis-Golgi |
| KEGG:00513 | 0.00269260965903 | 0.4 | MAN1A1 MAN1A2 | Various types of N-glycan biosynthesis |
| KEGG:00510 | 0.00403884103568 | 0.4 | MAN1A1 MAN1A2 | N-Glycan biosynthesis |
| REAC:R-HSA-6811438 | 0.0126969553517 | 0.4 | MAN1A1 MAN1A2 | Intra-Golgi traffic |
| GO:1904381 | 0.0135228859698 | 0.4 | MAN1A1 MAN1A2 | Golgi apparatus mannose trimming |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CLDND1 | ZDHHC8 | 0.995 | 0.924 | bioplex (CLDND1) bioplex_WMM gupta_WMM |
| CLDND1 | GOLGA7 | 0.973 | 0.886 | bioplex (CLDND1) bioplex_WMM |
| CLDND1 | MAN1A1 | 0.74 | 0.738 | bioplex (CLDND1) bioplex_WMM |
| CLDND1 | MAN1A2 | 0.124 | 0.396 | bioplex (CLDND1) bioplex_WMM |
| MAN1A1 | MAN1A2 | 0.01 | 0.116 | bioplex_WMM WMM_only |
| ZDHHC8 | GOLGA7 | 0.008 | 0.094 | bioplex_WMM WMM_only |
| MAN1A1 | ZDHHC8 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| MAN1A2 | ZDHHC8 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| MAN1A1 | GOLGA7 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| MAN1A2 | GOLGA7 | 0.007 | 0.001 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_05963 has an average edge precision of 0.331 which is ranked 4222 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CLDND1 | HuMAP2_00899 HuMAP2_02858 HuMAP2_05963 |
| ZDHHC8 | HuMAP2_00899 HuMAP2_02858 HuMAP2_05963 |
| GOLGA7 | HuMAP2_00899 HuMAP2_02199 HuMAP2_02858 HuMAP2_05963 |
| MAN1A2 | HuMAP2_00899 HuMAP2_05963 |
| MAN1A1 | HuMAP2_00899 HuMAP2_02142 HuMAP2_02858 HuMAP2_05963 |