hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05966
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ILF3 | Interleukin enhancer-binding factor 3 (Double-stranded RNA-binding protein 76) (DRBP76) (M-phase phosphoprotein 4) (MPP4) (Nuclear factor associated with dsRNA) (NFAR) (Nuclear factor of activated T-cells 90 kDa) (NF-AT-90) (Translational control protein 80) (TCP80) | UniProt NCBI |
| ILF2 | Interleukin enhancer-binding factor 2 (Nuclear factor of activated T-cells 45 kDa) | UniProt NCBI |
| SYNCRIP | Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | UniProt NCBI |
| KHDRBS1 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) | UniProt NCBI |
| STRBP | Spermatid perinuclear RNA-binding protein | UniProt NCBI |
| ZFR | Zinc finger RNA-binding protein (hZFR) (M-phase phosphoprotein homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003725 | 0.000216594058417 | 0.666666666667 | ZFR ILF3 ILF2 STRBP | double-stranded RNA binding |
| GO:0003727 | 0.000231008761032 | 0.666666666667 | ZFR ILF3 KHDRBS1 STRBP | single-stranded RNA binding |
| CORUM:5183 | 0.000234668084372 | 0.333333333333 | ILF3 ILF2 | DNA-PK-Ku-eIF2-NF90-NF45 complex |
| HPA:026010_13 | 0.00147271416647 | 0.5 | ILF3 ILF2 ZFR | liver; bile duct cells[Supported,High] |
| CORUM:1332 | 0.00158897110565 | 0.333333333333 | ILF3 ILF2 | Large Drosha complex |
| HPA:047010_13 | 0.00185452154089 | 0.5 | ILF3 ILF2 ZFR | soft tissue 1; adipocytes[Supported,High] |
| HPA:008010_13 | 0.00190059586168 | 0.5 | ILF3 ILF2 ZFR | cerebral cortex; endothelial cells[Supported,High] |
| HPA:048010_13 | 0.0026272950766 | 0.5 | ILF3 ILF2 ZFR | soft tissue 2; adipocytes[Supported,High] |
| HPA:026010_03 | 0.00450483352673 | 0.5 | ILF3 ILF2 ZFR | liver; bile duct cells[Uncertain,High] |
| HPA:031020_13 | 0.00484174312092 | 0.5 | ILF3 ILF2 ZFR | ovary; ovarian stroma cells[Supported,High] |
| HPA:047010_03 | 0.0057558927923 | 0.5 | ILF3 ILF2 ZFR | soft tissue 1; adipocytes[Uncertain,High] |
| HPA:046010_13 | 0.00585311327625 | 0.5 | ILF3 ILF2 ZFR | smooth muscle; smooth muscle cells[Supported,High] |
| HPA:048030_13 | 0.0062528373512 | 0.5 | ILF3 ILF2 ZFR | soft tissue 2; fibroblasts[Supported,High] |
| HPA:047030_13 | 0.00710551584535 | 0.5 | ILF3 ILF2 ZFR | soft tissue 1; fibroblasts[Supported,High] |
| HPA:048010_03 | 0.00767553017836 | 0.5 | ILF3 ILF2 ZFR | soft tissue 2; adipocytes[Uncertain,High] |
| HPA:031020_03 | 0.00864896230736 | 0.5 | ILF3 ILF2 ZFR | ovary; ovarian stroma cells[Uncertain,High] |
| HPA:008010_03 | 0.00864896230736 | 0.5 | ILF3 ILF2 ZFR | cerebral cortex; endothelial cells[Uncertain,High] |
| HPA:022010_13 | 0.00970050432156 | 0.5 | ILF3 ILF2 ZFR | hippocampus; glial cells[Supported,High] |
| HPA:011010_13 | 0.010686940244 | 0.5 | ILF3 ILF2 ZFR | colon; endothelial cells[Supported,High] |
| HPA:050010_13 | 0.0118926812045 | 0.5 | ILF3 ILF2 ZFR | spleen; cells in red pulp[Supported,High] |
| HPA:043010_13 | 0.0145660211017 | 0.5 | ILF3 ILF2 ZFR | skin 1; Langerhans[Supported,High] |
| HPA:041010_13 | 0.0145660211017 | 0.5 | ILF3 ILF2 ZFR | skeletal muscle; myocytes[Supported,High] |
| HPA:043020_13 | 0.0164222898738 | 0.5 | ILF3 ILF2 ZFR | skin 1; fibroblasts[Supported,High] |
| HPA:002020_13 | 0.0166160335558 | 0.5 | ILF3 ILF2 ZFR | appendix; lymphoid tissue[Supported,High] |
| HPA:024010_13 | 0.0174060390869 | 0.5 | ILF3 ILF2 ZFR | kidney; cells in glomeruli[Supported,High] |
| HPA:028010_13 | 0.0182203551373 | 0.5 | ILF3 ILF2 ZFR | lymph node; germinal center cells[Supported,High] |
| HPA:032020_13 | 0.0182203551373 | 0.5 | ILF3 ILF2 ZFR | pancreas; islets of Langerhans[Supported,High] |
| HPA:048030_03 | 0.018847255069 | 0.5 | ILF3 ILF2 ZFR | soft tissue 2; fibroblasts[Uncertain,High] |
| HPA:006010_13 | 0.0190593292701 | 0.5 | ILF3 ILF2 ZFR | caudate; glial cells[Supported,High] |
| HPA:022010_03 | 0.0197049502977 | 0.5 | ILF3 ILF2 ZFR | hippocampus; glial cells[Uncertain,High] |
| HPA:007020_13 | 0.0210389711895 | 0.5 | ILF3 ILF2 ZFR | cerebellum; cells in granular layer[Supported,High] |
| HPA:008020_13 | 0.0214964780915 | 0.5 | ILF3 ILF2 ZFR | cerebral cortex; glial cells[Supported,High] |
| HPA:021010_13 | 0.0219604733195 | 0.5 | ILF3 ILF2 ZFR | heart muscle; myocytes[Supported,High] |
| HPA:043040_13 | 0.022194917473 | 0.5 | ILF3 ILF2 ZFR | skin 1; melanocytes[Supported,High] |
| HPA:043030_13 | 0.0233918179533 | 0.5 | ILF3 ILF2 ZFR | skin 1; keratinocytes[Supported,High] |
| HPA:047030_03 | 0.0256515765772 | 0.5 | ILF3 ILF2 ZFR | soft tissue 1; fibroblasts[Uncertain,High] |
| HPA:027020_13 | 0.0259111542195 | 0.5 | ILF3 ILF2 ZFR | lung; pneumocytes[Supported,High] |
| HPA:028020_13 | 0.0264354692737 | 0.5 | ILF3 ILF2 ZFR | lymph node; non-germinal center cells[Supported,High] |
| HPA:046010_03 | 0.0264354692737 | 0.5 | ILF3 ILF2 ZFR | smooth muscle; smooth muscle cells[Uncertain,High] |
| HPA:006020_13 | 0.0275048868331 | 0.5 | ILF3 ILF2 ZFR | caudate; neuronal cells[Supported,High] |
| HPA:047040_12 | 0.0297280557391 | 0.5 | ILF3 ILF2 ZFR | soft tissue 1; peripheral nerve[Supported,Medium] |
| HPA:035010_13 | 0.0300139609548 | 0.5 | ILF3 ILF2 ZFR | placenta; decidual cells[Supported,High] |
| HPA:036010_13 | 0.0317673198783 | 0.5 | ILF3 ILF2 ZFR | prostate; glandular cells[Supported,High] |
| HPA:022020_13 | 0.033278695592 | 0.5 | ILF3 ILF2 ZFR | hippocampus; neuronal cells[Supported,High] |
| HPA:058010_13 | 0.035153614842 | 0.5 | ILF3 ILF2 ZFR | vagina; squamous epithelial cells[Supported,High] |
| HPA:007030_13 | 0.0361164666626 | 0.5 | ILF3 ILF2 ZFR | cerebellum; cells in molecular layer[Supported,High] |
| HPA:002020_03 | 0.0364412136813 | 0.5 | ILF3 ILF2 ZFR | appendix; lymphoid tissue[Uncertain,High] |
| HPA:056010_13 | 0.0367678675409 | 0.5 | ILF3 ILF2 ZFR | tonsil; germinal center cells[Supported,High] |
| HPA:040010_13 | 0.0384299204809 | 0.5 | ILF3 ILF2 ZFR | seminal vesicle; glandular cells[Supported,High] |
| GO:0003723 | 0.0386338629612 | 1.0 | ILF3 ZFR STRBP ILF2 SYNCRIP KHDRBS1 | RNA binding |
| HPA:050010_03 | 0.0387681239533 | 0.5 | ILF3 ILF2 ZFR | spleen; cells in red pulp[Uncertain,High] |
| HPA:007010_13 | 0.0391082704229 | 0.5 | ILF3 ILF2 ZFR | cerebellum; Purkinje cells[Supported,High] |
| HPA:056020_13 | 0.0391082704229 | 0.5 | ILF3 ILF2 ZFR | tonsil; non-germinal center cells[Supported,High] |
| HPA:006010_03 | 0.0404883892401 | 0.5 | ILF3 ILF2 ZFR | caudate; glial cells[Uncertain,High] |
| HPA:009010_13 | 0.0404883892401 | 0.5 | ILF3 ILF2 ZFR | cervix, uterine; glandular cells[Supported,High] |
| HPA:013020_13 | 0.0419000074614 | 0.5 | ILF3 ILF2 ZFR | endometrium 1; glandular cells[Supported,High] |
| CORUM:3055 | 0.0424488557459 | 0.333333333333 | ILF3 ILF2 | Nop56p-associated pre-rRNA complex |
| HPA:043010_03 | 0.0429795900804 | 0.5 | ILF3 ILF2 ZFR | skin 1; Langerhans[Uncertain,High] |
| HPA:030010_13 | 0.044077213876 | 0.5 | ILF3 ILF2 ZFR | oral mucosa; squamous epithelial cells[Supported,High] |
| HPA:008020_03 | 0.0459470526365 | 0.5 | ILF3 ILF2 ZFR | cerebral cortex; glial cells[Uncertain,High] |
| HPA:053010_13 | 0.0467092699772 | 0.5 | ILF3 ILF2 ZFR | testis; Leydig cells[Supported,High] |
| HPA:028010_03 | 0.0494420452986 | 0.5 | ILF3 ILF2 ZFR | lymph node; germinal center cells[Uncertain,High] |
| HPA:056030_13 | 0.0498407651214 | 0.5 | ILF3 ILF2 ZFR | tonsil; squamous epithelial cells[Supported,High] |
| CORUM:644 | 0.0499726005494 | 0.166666666667 | KHDRBS1 | ASPP1-SAM68 complex |
| CORUM:3080 | 0.0499726005494 | 0.166666666667 | ILF3 | ILF3-XPO5 complex |
| CORUM:2578 | 0.0499726005494 | 0.166666666667 | KHDRBS1 | Sam68-p120GAP complex |
| CORUM:3079 | 0.0499726005494 | 0.166666666667 | ILF3 | DGCR8-ILF3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ILF3 | ILF2 | 1.0 | 0.949 | hein_WMM youn (ILF3) bioplex (ILF2) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ZFR | ILF2 | 1.0 | 0.949 | bioplex (ILF2) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| ILF2 | SYNCRIP | 0.999 | 0.949 | hein_WMM youn (SYNCRIP) bioplex (ILF2,SYNCRIP) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| KHDRBS1 | SYNCRIP | 0.985 | 0.899 | hein_WMM youn (SYNCRIP) bioplex (SYNCRIP) bioplex_WMM Guru youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| ILF2 | STRBP | 0.936 | 0.85 | bioplex (ILF2,STRBP) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ILF2 | KHDRBS1 | 0.816 | 0.773 | hein_WMM bioplex (ILF2) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| ILF3 | STRBP | 0.813 | 0.773 | youn (ILF3) bioplex (STRBP) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ZFR | SYNCRIP | 0.04 | 0.268 | youn (SYNCRIP) bioplex (SYNCRIP) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| SYNCRIP | STRBP | 0.015 | 0.147 | youn (SYNCRIP) bioplex (STRBP,SYNCRIP) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| ILF3 | SYNCRIP | 0.015 | 0.145 | hein_WMM youn (ILF3,SYNCRIP) bioplex (SYNCRIP) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| ILF3 | KHDRBS1 | 0.012 | 0.146 | hein_WMM youn (ILF3) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| ZFR | STRBP | 0.011 | 0.148 | bioplex (STRBP) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| KHDRBS1 | STRBP | 0.007 | 0.01 | bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| ZFR | ILF3 | 0.005 | 0.007 | youn (ILF3) bioplex_WMM youn_WMM gupta_WMM treiber_WMM |
| ZFR | KHDRBS1 | 0.004 | 0.005 | bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_05966 has an average edge precision of 0.468 which is ranked 2726 out of all 6965 complexes.
Related Complexes