hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05967
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DOCK9 | Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1) | UniProt NCBI |
| DOCK10 | Dedicator of cytokinesis protein 10 (Zizimin-3) | UniProt NCBI |
| PAAT | Uncharacterized protein C10orf88 | UniProt NCBI |
| DOCK11 | Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-983231 | 0.000880763368668 | 0.75 | DOCK10 DOCK9 DOCK11 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-109582 | 0.033540764945 | 0.75 | DOCK10 DOCK9 DOCK11 | Hemostasis |
| GO:0002315 | 0.0405595771497 | 0.5 | DOCK11 DOCK10 | marginal zone B cell differentiation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DOCK9 | DOCK10 | 0.999 | 0.948 | bioplex (DOCK10) bioplex_WMM |
| DOCK9 | PAAT | 0.73 | 0.735 | bioplex (PAAT) bioplex_WMM |
| PAAT | DOCK11 | 0.612 | 0.674 | bioplex (PAAT) bioplex_WMM |
| DOCK9 | DOCK11 | 0.008 | 0.065 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_05967 has an average edge precision of 0.606 which is ranked 1911 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DOCK9 | HuMAP2_00371 HuMAP2_01713 HuMAP2_03644 HuMAP2_04351 HuMAP2_05967 |
| DOCK10 | HuMAP2_00371 HuMAP2_03644 HuMAP2_04351 HuMAP2_05967 |
| PAAT | HuMAP2_00371 HuMAP2_00785 HuMAP2_01713 HuMAP2_03644 HuMAP2_05967 |
| DOCK11 | HuMAP2_00371 HuMAP2_00668 HuMAP2_00785 HuMAP2_00950 HuMAP2_01713 HuMAP2_05967 HuMAP2_06314 |