hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05973
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| YRDC | YrdC domain-containing protein, mitochondrial (Dopamine receptor-interacting protein 3) (Ischemia/reperfusion-inducible protein homolog) (hIRIP) | UniProt NCBI |
| SPIN1 | Spindlin-1 (Ovarian cancer-related protein) (Spindlin1) | UniProt NCBI |
| TOPORS | E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3) | UniProt NCBI |
| SPIN2B | Spindlin-2B (Spindlin-like protein 2B) (SPIN-2) (SPIN-2B) | UniProt NCBI |
| SPINDOC | Spindlin interactor and repressor of chromatin-binding protein (SPIN1-docking protein) (SPIN-DOC) | UniProt NCBI |
| UBR7 | Putative E3 ubiquitin-protein ligase UBR7 (EC 2.3.2.27) (N-recognin-7) (RING-type E3 ubiquitin transferase UBR7) | UniProt NCBI |
| CGGBP1 | CGG triplet repeat-binding protein 1 (CGG-binding protein 1) (20 kDa CGG-binding protein) (p20-CGGBP DNA-binding protein) | UniProt NCBI |
| PAX3 | Paired box protein Pax-3 (HuP2) | UniProt NCBI |
| SPIN3 | Spindlin-3 (Spindlin-like protein 3) (SPIN-3) | UniProt NCBI |
| SPIN4 | Spindlin-4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035064 | 0.0018503338385 | 0.4 | SPIN2B SPIN3 SPIN1 SPIN4 | methylated histone binding |
| GO:0140034 | 0.0018503338385 | 0.4 | SPIN2B SPIN3 SPIN1 SPIN4 | methylation-dependent protein binding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SPINDOC | SPIN1 | 0.998 | 0.941 | bioplex (SPIN1,SPINDOC) bioplex_WMM boldt boldt_WMM |
| SPIN1 | SPIN2B | 0.995 | 0.923 | bioplex (SPIN1,SPIN2B) bioplex_WMM |
| CGGBP1 | SPIN2B | 0.972 | 0.886 | bioplex (SPIN2B) bioplex_WMM |
| SPINDOC | SPIN3 | 0.948 | 0.856 | bioplex (SPINDOC) bioplex_WMM |
| SPIN2B | SPIN4 | 0.919 | 0.841 | bioplex (SPIN2B) bioplex_WMM |
| CGGBP1 | SPIN1 | 0.656 | 0.694 | bioplex (SPIN1) bioplex_WMM |
| SPIN1 | SPIN4 | 0.596 | 0.666 | bioplex (SPIN1) bioplex_WMM |
| SPINDOC | SPIN2B | 0.5 | 0.621 | bioplex (SPIN2B,SPINDOC) bioplex_WMM |
| UBR7 | SPIN2B | 0.17 | 0.426 | bioplex (SPIN2B) bioplex_WMM |
| PAX3 | SPIN1 | 0.129 | 0.399 | bioplex (SPIN1) bioplex_WMM |
| TOPORS | SPIN1 | 0.074 | 0.357 | bioplex (SPIN1) bioplex_WMM |
| SPIN1 | YRDC | 0.06 | 0.336 | bioplex (SPIN1) bioplex_WMM |
| YRDC | SPIN4 | 0.012 | 0.146 | bioplex_WMM WMM_only |
| SPIN2B | YRDC | 0.012 | 0.147 | bioplex (SPIN2B) bioplex_WMM |
| SPINDOC | SPIN4 | 0.012 | 0.149 | bioplex_WMM WMM_only |
| CGGBP1 | SPIN4 | 0.011 | 0.142 | bioplex_WMM WMM_only |
| SPINDOC | YRDC | 0.011 | 0.145 | bioplex_WMM WMM_only |
| CGGBP1 | YRDC | 0.011 | 0.145 | bioplex_WMM WMM_only |
| CGGBP1 | SPINDOC | 0.011 | 0.145 | bioplex_WMM WMM_only |
| TOPORS | SPIN4 | 0.01 | 0.121 | bioplex_WMM WMM_only |
| SPIN3 | SPIN2B | 0.01 | 0.099 | bioplex_WMM WMM_only |
| TOPORS | YRDC | 0.01 | 0.103 | bioplex_WMM WMM_only |
| SPIN1 | SPIN3 | 0.009 | 0.112 | bioplex_WMM WMM_only |
| TOPORS | SPINDOC | 0.009 | 0.109 | bioplex_WMM WMM_only |
| CGGBP1 | TOPORS | 0.009 | 0.107 | bioplex_WMM WMM_only |
| PAX3 | SPIN4 | 0.009 | 0.098 | bioplex_WMM WMM_only |
| UBR7 | SPIN4 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| PAX3 | YRDC | 0.008 | 0.086 | bioplex_WMM WMM_only |
| PAX3 | SPINDOC | 0.008 | 0.092 | bioplex_WMM WMM_only |
| UBR7 | YRDC | 0.008 | 0.088 | bioplex_WMM WMM_only |
| UBR7 | SPINDOC | 0.008 | 0.085 | bioplex_WMM WMM_only |
| CGGBP1 | PAX3 | 0.008 | 0.083 | bioplex_WMM WMM_only |
| PAX3 | SPIN2B | 0.008 | 0.084 | bioplex_WMM WMM_only |
| CGGBP1 | UBR7 | 0.008 | 0.079 | bioplex_WMM WMM_only |
| UBR7 | SPIN1 | 0.008 | 0.063 | bioplex_WMM WMM_only |
| TOPORS | PAX3 | 0.008 | 0.035 | bioplex_WMM WMM_only |
| TOPORS | UBR7 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| TOPORS | SPIN3 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| TOPORS | SPIN2B | 0.004 | 0.009 | bioplex (SPIN2B) bioplex_WMM |
Images
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Complex HuMAP2_05973 has an average edge precision of 0.27 which is ranked 5020 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| YRDC | HuMAP2_05686 HuMAP2_05973 |
| SPIN1 | HuMAP2_03736 HuMAP2_05686 HuMAP2_05906 HuMAP2_05973 |
| TOPORS | HuMAP2_01088 HuMAP2_03225 HuMAP2_05973 HuMAP2_06158 |
| SPIN2B | HuMAP2_05686 HuMAP2_05906 HuMAP2_05973 |
| SPINDOC | HuMAP2_03736 HuMAP2_03887 HuMAP2_05686 HuMAP2_05973 |
| UBR7 | HuMAP2_01408 HuMAP2_01768 HuMAP2_04079 HuMAP2_05686 HuMAP2_05973 |
| CGGBP1 | HuMAP2_00943 HuMAP2_05686 HuMAP2_05906 HuMAP2_05973 |
| PAX3 | HuMAP2_01593 HuMAP2_02253 HuMAP2_03121 HuMAP2_05973 HuMAP2_06878 |
| SPIN3 | HuMAP2_03736 HuMAP2_03887 HuMAP2_05973 |
| SPIN4 | HuMAP2_05686 HuMAP2_05906 HuMAP2_05973 |