hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05977
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KCNAB2 | Voltage-gated potassium channel subunit beta-2 (EC 1.1.1.-) (K(+) channel subunit beta-2) (Kv-beta-2) (hKvbeta2) | UniProt NCBI |
| KCNAB1 | Voltage-gated potassium channel subunit beta-1 (EC 1.1.1.-) (K(+) channel subunit beta-1) (Kv-beta-1) | UniProt NCBI |
| KCNAB3 | Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3) | UniProt NCBI |
| TNNC2 | Troponin C, skeletal muscle | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 8.82452886806e-06 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 8.36972120253e-05 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | Potassium Channels |
| WP:WP702 | 0.000147158600107 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | Metapathway biotransformation Phase I and II |
| GO:0015459 | 0.00217043933003 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | potassium channel regulator activity |
| REAC:R-HSA-112316 | 0.00869575285043 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | Neuronal System |
| GO:0099106 | 0.0198185309013 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | ion channel regulator activity |
| GO:0016247 | 0.0410761885593 | 0.75 | KCNAB3 KCNAB1 KCNAB2 | channel regulator activity |
| CORUM:7389 | 0.0499140284799 | 0.25 | KCNAB2 | Potassium channel complex (KCNA1, KCNA2, KCNAB2) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KCNAB1 | KCNAB2 | 1.0 | 0.949 | bioplex (KCNAB1) bioplex_WMM |
| KCNAB2 | KCNAB3 | 0.811 | 0.771 | bioplex (KCNAB3) bioplex_WMM |
| TNNC2 | KCNAB2 | 0.03 | 0.236 | bioplex (KCNAB2) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_05977 has an average edge precision of 0.652 which is ranked 1640 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KCNAB2 | HuMAP2_03963 HuMAP2_05977 |
| KCNAB1 | HuMAP2_03963 HuMAP2_05977 |
| KCNAB3 | HuMAP2_03963 HuMAP2_05977 |
| TNNC2 | HuMAP2_03899 HuMAP2_04612 HuMAP2_05977 HuMAP2_06061 |