hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_05985
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HINT1 | Histidine triad nucleotide-binding protein 1 (EC 3.-.-.-) (Adenosine 5'-monophosphoramidase) (Protein kinase C inhibitor 1) (Protein kinase C-interacting protein 1) (PKCI-1) | UniProt NCBI |
| PRDX5 | Peroxiredoxin-5, mitochondrial (EC 1.11.1.15) (Alu corepressor 1) (Antioxidant enzyme B166) (AOEB166) (Liver tissue 2D-page spot 71B) (PLP) (Peroxiredoxin V) (Prx-V) (Peroxisomal antioxidant enzyme) (TPx type VI) (Thioredoxin peroxidase PMP20) | UniProt NCBI |
| PRDX6 | Peroxiredoxin-6 (EC 1.11.1.15) (1-Cys peroxiredoxin) (1-Cys PRX) (24 kDa protein) (Acidic calcium-independent phospholipase A2) (aiPLA2) (EC 3.1.1.4) (Antioxidant protein 2) (Liver 2D page spot 40) (Non-selenium glutathione peroxidase) (NSGPx) (Red blood cells page spot 12) | UniProt NCBI |
| LACTB2 | Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2) | UniProt NCBI |
| PNP | Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) | UniProt NCBI |
| COX17 | Cytochrome c oxidase copper chaperone | UniProt NCBI |
| PARK7 | Protein/nucleic acid deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase) (Oncogene DJ1) (Parkinson disease protein 7) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) | UniProt NCBI |
| SPR | Sepiapterin reductase (SPR) (EC 1.1.1.153) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6208 | 0.0248670854284 | 0.125 | PNP | PNP homotrimer complex |
| CORUM:5830 | 0.0497224828424 | 0.125 | PARK7 | DJ-1-SNCA complex, high molecular weight complex |
| CORUM:5837 | 0.0497224828424 | 0.125 | PARK7 | PPD complex |
| CORUM:7324 | 0.0497224828424 | 0.125 | HINT1 | HINT1-TIP60 complex |
| CORUM:7326 | 0.0497224828424 | 0.125 | HINT1 | HINT1-SP1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LACTB2 | PARK7 | 0.973 | 0.886 | bioplex (LACTB2) bioplex_WMM fraction |
| PRDX5 | HINT1 | 0.355 | 0.54 | bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| PRDX5 | LACTB2 | 0.263 | 0.481 | bioplex_WMM fraction |
| PRDX5 | SPR | 0.154 | 0.414 | fraction treiber_WMM |
| HINT1 | LACTB2 | 0.137 | 0.406 | bioplex_WMM fraction |
| PARK7 | PRDX6 | 0.126 | 0.399 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| HINT1 | PARK7 | 0.107 | 0.373 | bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| PRDX5 | PARK7 | 0.106 | 0.373 | bioplex (PRDX5) bioplex_WMM gupta_WMM fraction treiber_WMM |
| PARK7 | PNP | 0.098 | 0.357 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| PRDX5 | COX17 | 0.069 | 0.348 | fraction |
| COX17 | PARK7 | 0.059 | 0.328 | youn_WMM fraction |
| HINT1 | PRDX6 | 0.054 | 0.303 | bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| LACTB2 | PRDX6 | 0.033 | 0.252 | bioplex (LACTB2) bioplex_WMM fraction |
| LACTB2 | COX17 | 0.022 | 0.203 | fraction |
| HINT1 | PNP | 0.013 | 0.142 | bioplex_WMM gupta_WMM fraction |
| PRDX5 | PNP | 0.007 | 0.005 | bioplex_WMM gupta_WMM WMM_only treiber_WMM |
| SPR | PARK7 | 0.006 | 0.008 | bioplex_WMM fraction treiber_WMM |
| LACTB2 | PNP | 0.006 | 0.006 | bioplex_WMM WMM_only |
| SPR | PRDX6 | 0.004 | 0.011 | bioplex_WMM fraction treiber_WMM |
| SPR | COX17 | 0.004 | 0.011 | fraction |
| PRDX6 | PNP | 0.0 | 0.011 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| COX17 | PNP | 0.0 | 0.011 | fraction |
| SPR | LACTB2 | 0.0 | 0.011 | bioplex_WMM fraction |
| COX17 | PRDX6 | 0.0 | 0.009 | youn_WMM fraction |
| SPR | PNP | 0.0 | 0.001 | bioplex_WMM fraction treiber_WMM |
| PRDX5 | PRDX6 | 0.0 | 0.003 | bioplex (PRDX5) bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| SPR | HINT1 | 0.0 | 0.001 | bioplex_WMM fraction |
| HINT1 | COX17 | 0.0 | 0.0 | youn_WMM fraction |
Images
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Complex HuMAP2_05985 has an average edge precision of 0.21 which is ranked 6019 out of all 6965 complexes.
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