hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_05989
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RIT1 | GTP-binding protein Rit1 (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1) | UniProt NCBI |
| LZTR1 | Leucine-zipper-like transcriptional regulator 1 (LZTR-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0011381 | 0.000303888373596 | 1.0 | RIT1 LZTR1 | Aplasia of the semicircular canal |
| HP:0011380 | 0.000510933199563 | 1.0 | RIT1 LZTR1 | Morphological abnormality of the semicircular canal |
| HP:0011376 | 0.000701280862145 | 1.0 | RIT1 LZTR1 | Morphological abnormality of the vestibule of the inner ear |
| HP:0002212 | 0.000701280862145 | 1.0 | RIT1 LZTR1 | Curly hair |
| HP:0000391 | 0.00108531561999 | 1.0 | RIT1 LZTR1 | Thickened helices |
| HP:0010318 | 0.00176322045339 | 1.0 | RIT1 LZTR1 | Aplasia/Hypoplasia of the abdominal wall musculature |
| HP:0000476 | 0.00198696244274 | 1.0 | RIT1 LZTR1 | Cystic hygroma |
| HP:0011869 | 0.00210384258643 | 1.0 | RIT1 LZTR1 | Abnormal platelet function |
| HP:0010991 | 0.00330603835011 | 1.0 | RIT1 LZTR1 | Abnormal morphology of the abdominal musculature |
| HP:0002208 | 0.00345631282057 | 1.0 | RIT1 LZTR1 | Coarse hair |
| HP:0004415 | 0.00360992672371 | 1.0 | RIT1 LZTR1 | Pulmonary artery stenosis |
| HP:0000995 | 0.00360992672371 | 1.0 | RIT1 LZTR1 | Melanocytic nevus |
| HP:0001641 | 0.00360992672371 | 1.0 | RIT1 LZTR1 | Abnormal pulmonary valve morphology |
| HP:0100625 | 0.00392717282801 | 1.0 | RIT1 LZTR1 | Enlarged thorax |
| HP:0000474 | 0.00425777666302 | 1.0 | RIT1 LZTR1 | Thickened nuchal skin fold |
| HP:0001004 | 0.00460173822874 | 1.0 | RIT1 LZTR1 | Lymphedema |
| HP:0011390 | 0.00477872816061 | 1.0 | RIT1 LZTR1 | Morphological abnormality of the inner ear |
| HP:0002974 | 0.00571376931014 | 1.0 | RIT1 LZTR1 | Radioulnar synostosis |
| HP:0011425 | 0.00716308309191 | 1.0 | RIT1 LZTR1 | Fetal ultrasound soft marker |
| HP:0030966 | 0.00829849020205 | 1.0 | RIT1 LZTR1 | Abnormal pulmonary artery morphology |
| HP:0002162 | 0.00829849020205 | 1.0 | RIT1 LZTR1 | Low posterior hairline |
| HP:0030141 | 0.00829849020205 | 1.0 | RIT1 LZTR1 | Abnormality of the posterior hairline |
| HP:0040157 | 0.00926692567834 | 1.0 | RIT1 LZTR1 | Abnormal intermamillary distance |
| HP:0006610 | 0.00926692567834 | 1.0 | RIT1 LZTR1 | Wide intermamillary distance |
| HP:0001642 | 0.0105526072589 | 1.0 | RIT1 LZTR1 | Pulmonic stenosis |
| HP:0000465 | 0.0105526072589 | 1.0 | RIT1 LZTR1 | Webbed neck |
| HP:0004414 | 0.0105526072589 | 1.0 | RIT1 LZTR1 | Abnormality of the pulmonary artery |
| HP:0100238 | 0.0136749768118 | 1.0 | RIT1 LZTR1 | Synostosis involving bones of the upper limbs |
| HP:0000044 | 0.0139788651854 | 1.0 | RIT1 LZTR1 | Hypogonadotrophic hypogonadism |
| HP:0011039 | 0.0149105669023 | 1.0 | RIT1 LZTR1 | Abnormality of the helix |
| HP:0000325 | 0.0149105669023 | 1.0 | RIT1 LZTR1 | Triangular face |
| HP:0031654 | 0.0158723235132 | 1.0 | RIT1 LZTR1 | Abnormal pulmonary valve physiology |
| HP:0003764 | 0.0165301917506 | 1.0 | RIT1 LZTR1 | Nevus |
| HP:0004930 | 0.0168641350182 | 1.0 | RIT1 LZTR1 | Abnormality of the pulmonary vasculature |
| HP:0000768 | 0.0218899811969 | 1.0 | RIT1 LZTR1 | Pectus carinatum |
| HP:0002997 | 0.0234461568244 | 1.0 | RIT1 LZTR1 | Abnormality of the ulna |
| HP:0000179 | 0.0302051685624 | 1.0 | RIT1 LZTR1 | Thick lower lip vermilion |
| HP:0010719 | 0.032028498804 | 1.0 | RIT1 LZTR1 | Abnormality of hair texture |
| HP:0009553 | 0.0329602005208 | 1.0 | RIT1 LZTR1 | Abnormality of the hairline |
| HP:0100240 | 0.0339052599684 | 1.0 | RIT1 LZTR1 | Synostosis of joints |
| HP:0004404 | 0.0348636771466 | 1.0 | RIT1 LZTR1 | Abnormal nipple morphology |
| HP:0011361 | 0.0388309231668 | 1.0 | RIT1 LZTR1 | Congenital abnormal hair pattern |
| HP:0001928 | 0.0403737410635 | 1.0 | RIT1 LZTR1 | Abnormality of coagulation |
| HP:0002818 | 0.0424775836499 | 1.0 | RIT1 LZTR1 | Abnormality of the radius |
| HP:0005692 | 0.0462878763342 | 1.0 | RIT1 LZTR1 | Joint hyperflexibility |
| HP:0010720 | 0.047406586281 | 1.0 | RIT1 LZTR1 | Abnormal hair pattern |
| HP:0040072 | 0.0485386539584 | 1.0 | RIT1 LZTR1 | Abnormality of forearm bone |
| HP:0002973 | 0.0496840793666 | 1.0 | RIT1 LZTR1 | Abnormality of the forearm |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RIT1 | LZTR1 | 0.048 | 0.296 | bioplex (RIT1) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_05989 has an average edge precision of 0.296 which is ranked 4654 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RIT1 | HuMAP2_01421 HuMAP2_05989 |
| LZTR1 | HuMAP2_01421 HuMAP2_01650 HuMAP2_05563 HuMAP2_05989 |