hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06012
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KANK1 | KN motif and ankyrin repeat domain-containing protein 1 (Ankyrin repeat domain-containing protein 15) (Kidney ankyrin repeat-containing protein) | UniProt NCBI |
| ARR3 | Arrestin-C (Cone arrestin) (C-arrestin) (cArr) (Retinal cone arrestin-3) (X-arrestin) | UniProt NCBI |
| ARRB2 | Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0002031 | 0.0486736709081 | 0.666666666667 | ARR3 ARRB2 | G protein-coupled receptor internalization |
| CORUM:6805 | 0.0499776345577 | 0.333333333333 | ARRB2 | S1PR1-beta-arrestin 2 complex, ApoM(+)HDL-S1P stimulated |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARR3 | ARRB2 | 0.95 | 0.858 | bioplex (ARRB2) bioplex_WMM |
| KANK1 | ARRB2 | 0.062 | 0.345 | bioplex (ARRB2) bioplex_WMM |
| KANK1 | ARR3 | 0.008 | 0.091 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06012 has an average edge precision of 0.431 which is ranked 3014 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KANK1 | HuMAP2_00647 HuMAP2_02112 HuMAP2_03451 HuMAP2_06012 |
| ARR3 | HuMAP2_01749 HuMAP2_02112 HuMAP2_06012 |
| ARRB2 | HuMAP2_01749 HuMAP2_02112 HuMAP2_06012 |