hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06013
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RIPK2 | Receptor-interacting serine/threonine-protein kinase 2 (EC 2.7.11.1) (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2) | UniProt NCBI |
| STRAP | Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD) | UniProt NCBI |
| SZRD1 | SUZ domain-containing protein 1 (Putative MAPK-activating protein PM18/PM20/PM22) | UniProt NCBI |
| C11orf68 | UPF0696 protein C11orf68 (Basophilic leukemia-expressed protein Bles03) (Protein p5326) | UniProt NCBI |
| LARP6 | La-related protein 6 (Acheron) (Achn) (La ribonucleoprotein domain family member 6) | UniProt NCBI |
| GEMIN5 | Gem-associated protein 5 (Gemin5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1751 | 0.000301662071994 | 0.333333333333 | GEMIN5 STRAP | SMN complex |
| CORUM:1143 | 0.000878902571644 | 0.333333333333 | GEMIN5 STRAP | SMN complex |
| CORUM:3298 | 0.0499726005494 | 0.166666666667 | GEMIN5 | SMN complex (GEMIN2,5, SMN) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STRAP | LARP6 | 1.0 | 0.949 | youn (STRAP) bioplex (STRAP) bioplex_WMM treiber_WMM |
| STRAP | SZRD1 | 0.998 | 0.935 | hein_WMM youn (STRAP) bioplex (STRAP,SZRD1) bioplex_WMM youn_WMM hein (STRAP) |
| STRAP | C11orf68 | 0.801 | 0.765 | bioplex (STRAP) bioplex_WMM |
| STRAP | GEMIN5 | 0.684 | 0.711 | hein_WMM youn (STRAP) bioplex (STRAP) bioplex_WMM youn_WMM hein (GEMIN5) gupta_WMM treiber_WMM |
| STRAP | RIPK2 | 0.05 | 0.298 | bioplex (STRAP) bioplex_WMM youn_WMM gupta_WMM |
| LARP6 | C11orf68 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| RIPK2 | C11orf68 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| LARP6 | RIPK2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SZRD1 | LARP6 | 0.009 | 0.097 | bioplex_WMM youn_WMM WMM_only |
| SZRD1 | RIPK2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| SZRD1 | C11orf68 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| LARP6 | GEMIN5 | 0.008 | 0.044 | bioplex_WMM youn_WMM WMM_only |
| RIPK2 | GEMIN5 | 0.008 | 0.042 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| C11orf68 | GEMIN5 | 0.008 | 0.042 | bioplex_WMM WMM_only |
| SZRD1 | GEMIN5 | 0.007 | 0.01 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_06013 has an average edge precision of 0.29 which is ranked 4748 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RIPK2 | HuMAP2_01368 HuMAP2_03787 HuMAP2_06013 |
| STRAP | HuMAP2_00065 HuMAP2_01368 HuMAP2_03787 HuMAP2_05882 HuMAP2_06013 HuMAP2_06611 |
| SZRD1 | HuMAP2_01368 HuMAP2_03787 HuMAP2_06013 HuMAP2_06611 |
| C11orf68 | HuMAP2_01368 HuMAP2_03787 HuMAP2_06013 HuMAP2_06611 |
| LARP6 | HuMAP2_01368 HuMAP2_03787 HuMAP2_06013 HuMAP2_06611 |
| GEMIN5 | HuMAP2_01368 HuMAP2_02139 HuMAP2_02196 HuMAP2_02424 HuMAP2_06013 |