hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06026
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR26 | WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2) | UniProt NCBI |
| MAEA | E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP) | UniProt NCBI |
| GID8 | Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1) | UniProt NCBI |
| GID4 | Glucose-induced degradation protein 4 homolog (Vacuolar import and degradation protein 24 homolog) | UniProt NCBI |
| HTRA2 | Serine protease HTRA2, mitochondrial (EC 3.4.21.108) (High temperature requirement protein A2) (HtrA2) (Omi stress-regulated endoprotease) (Serine protease 25) (Serine proteinase OMI) | UniProt NCBI |
| RANBP9 | Ran-binding protein 9 (RanBP9) (BPM-L) (BPM90) (Ran-binding protein M) (RanBPM) (RanBP7) | UniProt NCBI |
| RANBP10 | Ran-binding protein 10 (RanBP10) | UniProt NCBI |
| ARMC8 | Armadillo repeat-containing protein 8 | UniProt NCBI |
| ZMYND19 | Zinc finger MYND domain-containing protein 19 (Melanin-concentrating hormone receptor 1-interacting zinc finger protein) (MCH-R1-interacting zinc finger protein) | UniProt NCBI |
| YPEL5 | Protein yippee-like 5 | UniProt NCBI |
| TDGF1 | Teratocarcinoma-derived growth factor 1 (Cripto-1 growth factor) (CRGF) (Epidermal growth factor-like cripto protein CR1) | UniProt NCBI |
| RMND5B | E3 ubiquitin-protein transferase RMND5B (EC 2.3.2.27) (Protein RMD5 homolog B) | UniProt NCBI |
| MKLN1 | Muskelin | UniProt NCBI |
| RMND5A | E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4352 | 6.79258510057e-22 | 0.928571428571 | MKLN1 GID4 YPEL5 HTRA2 ZMYND19 RANBP9 ARMC8 GID8 RANBP10 RMND5A MAEA WDR26 RMND5B | Ciliary landscape |
| CORUM:3071 | 1.74470635107e-14 | 0.357142857143 | MKLN1 RANBP9 RMND5A ARMC8 MAEA | CTLH complex |
| GO:0000151 | 9.25829629309e-11 | 0.714285714286 | MKLN1 GID4 YPEL5 RANBP9 ARMC8 GID8 RANBP10 RMND5A MAEA WDR26 | ubiquitin ligase complex |
| GO:0034657 | 2.44199569133e-08 | 0.285714285714 | MAEA ARMC8 RMND5B RMND5A | GID complex |
| CORUM:639 | 1.40594241297e-07 | 0.214285714286 | RANBP9 GID8 MKLN1 | RANBPM-Muskelin-TWA1-HSMpp8 complex |
| GO:1990234 | 2.05416317052e-06 | 0.714285714286 | MKLN1 GID4 YPEL5 RANBP9 ARMC8 GID8 RANBP10 RMND5A MAEA WDR26 | transferase complex |
| GO:1902494 | 1.23295189921e-05 | 0.785714285714 | MKLN1 GID4 YPEL5 HTRA2 RANBP9 ARMC8 GID8 RANBP10 RMND5A MAEA WDR26 | catalytic complex |
| WP:000000 | 0.00103744873361 | 0.928571428571 | MKLN1 GID4 YPEL5 HTRA2 ZMYND19 RANBP9 ARMC8 GID8 RANBP10 RMND5A MAEA WDR26 RMND5B | WIKIPATHWAYS |
| REAC:R-HSA-8851805 | 0.00746879685583 | 0.142857142857 | RANBP9 RANBP10 | MET activates RAS signaling |
| CORUM:641 | 0.0499987143188 | 0.0714285714286 | RANBP9 | RANBPM-SMP1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RMND5A | WDR26 | 1.0 | 0.949 | bioplex (RMND5A) bioplex_WMM boldt (RMND5A,WDR26) youn_WMM boldt_WMM |
| RMND5A | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| RANBP9 | GID8 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (GID8,RANBP9) youn_WMM Malo fraction boldt_WMM |
| RMND5A | RANBP10 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (RANBP10,RMND5A) boldt_WMM |
| RANBP9 | MAEA | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (MAEA,RANBP9) youn_WMM Malo fraction boldt_WMM |
| RMND5A | RANBP9 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (RANBP9,RMND5A) youn_WMM boldt_WMM |
| RMND5A | ARMC8 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (ARMC8,RMND5A) boldt_WMM |
| RMND5A | MKLN1 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (MKLN1,RMND5A) youn_WMM boldt_WMM |
| GID8 | RANBP10 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt Malo fraction boldt_WMM |
| RMND5A | MAEA | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt youn_WMM boldt_WMM |
| WDR26 | RANBP10 | 1.0 | 0.949 | bioplex_WMM boldt (RANBP10,WDR26) Malo fraction boldt_WMM |
| RANBP10 | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (RANBP10,YPEL5) hein (YPEL5) boldt_WMM |
| RANBP9 | MKLN1 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (MKLN1,RANBP9) youn_WMM hein (MKLN1) boldt_WMM |
| RANBP9 | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (RANBP9,YPEL5) hein (YPEL5) boldt_WMM |
| RMND5A | GID4 | 1.0 | 0.949 | bioplex (RMND5A) bioplex_WMM boldt (RMND5A) boldt_WMM |
| ARMC8 | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (ARMC8,YPEL5) hein (YPEL5) boldt_WMM |
| RMND5A | GID8 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (GID8,RMND5A) youn_WMM boldt_WMM |
| MAEA | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| GID8 | YPEL5 | 0.999 | 0.949 | hein_WMM bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| GID8 | MKLN1 | 0.995 | 0.923 | hein_WMM bioplex_WMM boldt youn_WMM hein (MKLN1) boldt_WMM |
| RMND5A | ZMYND19 | 0.965 | 0.874 | bioplex (RMND5A) bioplex_WMM boldt boldt_WMM |
| RANBP9 | RANBP10 | 0.958 | 0.863 | hein_WMM bioplex_WMM boldt (RANBP10,RANBP9) boldt_WMM |
| RANBP10 | ARMC8 | 0.942 | 0.855 | hein_WMM bioplex_WMM boldt (ARMC8,RANBP10) boldt_WMM |
| MAEA | ARMC8 | 0.939 | 0.85 | hein_WMM bioplex_WMM boldt (ARMC8,MAEA) youn_WMM boldt_WMM |
| MAEA | RANBP10 | 0.937 | 0.85 | hein_WMM bioplex_WMM boldt (MAEA,RANBP10) boldt_WMM |
| RANBP9 | ARMC8 | 0.929 | 0.845 | hein_WMM bioplex_WMM boldt (ARMC8,RANBP9) youn_WMM boldt_WMM |
| MKLN1 | YPEL5 | 0.908 | 0.831 | hein_WMM bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| RANBP9 | WDR26 | 0.845 | 0.789 | bioplex_WMM boldt (RANBP9,WDR26) youn_WMM boldt_WMM |
| MAEA | MKLN1 | 0.787 | 0.757 | hein_WMM bioplex_WMM boldt (MAEA,MKLN1) youn_WMM boldt_WMM |
| WDR26 | MAEA | 0.737 | 0.738 | bioplex_WMM boldt (MAEA,WDR26) youn_WMM boldt_WMM |
| ARMC8 | MKLN1 | 0.736 | 0.738 | hein_WMM bioplex_WMM boldt (ARMC8,MKLN1) boldt_WMM |
| GID8 | MAEA | 0.728 | 0.735 | hein_WMM bioplex_WMM boldt (GID8,MAEA) youn_WMM boldt_WMM |
| RANBP10 | GID4 | 0.601 | 0.671 | bioplex_WMM boldt (RANBP10) boldt_WMM |
| ARMC8 | GID4 | 0.553 | 0.646 | bioplex_WMM boldt (ARMC8) boldt_WMM |
| WDR26 | ARMC8 | 0.531 | 0.636 | bioplex_WMM boldt (ARMC8,WDR26) youn_WMM boldt_WMM |
| RMND5A | HTRA2 | 0.458 | 0.596 | bioplex (RMND5A) bioplex_WMM boldt youn_WMM boldt_WMM |
| MKLN1 | GID4 | 0.444 | 0.587 | bioplex_WMM boldt (MKLN1) boldt_WMM |
| RANBP9 | GID4 | 0.432 | 0.578 | bioplex_WMM boldt (RANBP9) boldt_WMM |
| WDR26 | YPEL5 | 0.397 | 0.557 | bioplex_WMM boldt (WDR26,YPEL5) boldt_WMM |
| GID8 | ARMC8 | 0.374 | 0.546 | hein_WMM bioplex_WMM boldt (ARMC8) youn_WMM boldt_WMM |
| WDR26 | GID8 | 0.336 | 0.527 | bioplex_WMM boldt (GID8,WDR26) youn_WMM boldt_WMM |
| MAEA | GID4 | 0.326 | 0.515 | bioplex_WMM boldt (MAEA) boldt_WMM |
| WDR26 | TDGF1 | 0.152 | 0.409 | bioplex (TDGF1) bioplex_WMM |
| MKLN1 | ZMYND19 | 0.139 | 0.406 | bioplex_WMM boldt (MKLN1) boldt_WMM |
| WDR26 | GID4 | 0.127 | 0.398 | bioplex_WMM boldt (WDR26) boldt_WMM |
| RANBP10 | MKLN1 | 0.116 | 0.387 | hein_WMM bioplex_WMM boldt boldt_WMM |
| WDR26 | MKLN1 | 0.095 | 0.359 | bioplex_WMM boldt (MKLN1) youn_WMM boldt_WMM |
| GID8 | GID4 | 0.095 | 0.357 | bioplex_WMM boldt boldt_WMM |
| ARMC8 | TDGF1 | 0.049 | 0.294 | bioplex (TDGF1) bioplex_WMM |
| YPEL5 | GID4 | 0.048 | 0.294 | bioplex_WMM boldt boldt_WMM |
| MAEA | RMND5B | 0.043 | 0.27 | bioplex_WMM boldt (MAEA,RMND5B) boldt_WMM |
| ARMC8 | ZMYND19 | 0.037 | 0.265 | bioplex_WMM boldt (ARMC8) boldt_WMM |
| RANBP9 | ZMYND19 | 0.033 | 0.251 | bioplex_WMM boldt (RANBP9) boldt_WMM |
| RMND5A | TDGF1 | 0.031 | 0.241 | bioplex (TDGF1) bioplex_WMM |
| ARMC8 | RMND5B | 0.029 | 0.232 | bioplex_WMM boldt (ARMC8,RMND5B) boldt_WMM |
| TDGF1 | RMND5B | 0.029 | 0.231 | bioplex (TDGF1) bioplex_WMM |
| MAEA | ZMYND19 | 0.027 | 0.223 | bioplex_WMM boldt boldt_WMM |
| GID4 | ZMYND19 | 0.025 | 0.218 | bioplex_WMM boldt boldt_WMM |
| HTRA2 | MAEA | 0.022 | 0.207 | bioplex_WMM boldt (MAEA) youn_WMM boldt_WMM |
| WDR26 | ZMYND19 | 0.02 | 0.185 | bioplex_WMM boldt boldt_WMM |
| GID8 | TDGF1 | 0.02 | 0.186 | bioplex (TDGF1) bioplex_WMM |
| RANBP10 | ZMYND19 | 0.018 | 0.177 | bioplex_WMM boldt boldt_WMM |
| WDR26 | RMND5B | 0.017 | 0.177 | bioplex_WMM boldt (RMND5B) boldt_WMM |
| HTRA2 | RANBP10 | 0.017 | 0.172 | bioplex_WMM boldt (RANBP10) boldt_WMM |
| HTRA2 | WDR26 | 0.017 | 0.169 | bioplex_WMM boldt (WDR26) youn_WMM boldt_WMM |
| YPEL5 | ZMYND19 | 0.016 | 0.161 | bioplex_WMM boldt boldt_WMM |
| RANBP9 | RMND5B | 0.016 | 0.16 | bioplex_WMM boldt (RMND5B) boldt_WMM |
| HTRA2 | ARMC8 | 0.015 | 0.147 | bioplex_WMM boldt (ARMC8) boldt_WMM |
| YPEL5 | RMND5B | 0.015 | 0.145 | bioplex_WMM boldt (RMND5B) boldt_WMM |
| HTRA2 | MKLN1 | 0.014 | 0.138 | bioplex_WMM boldt (MKLN1) youn_WMM boldt_WMM |
| ZMYND19 | RMND5B | 0.014 | 0.141 | bioplex_WMM boldt boldt_WMM |
| GID8 | ZMYND19 | 0.012 | 0.15 | bioplex_WMM boldt boldt_WMM |
| HTRA2 | GID4 | 0.012 | 0.147 | bioplex_WMM boldt boldt_WMM |
| MAEA | TDGF1 | 0.011 | 0.149 | bioplex (TDGF1) bioplex_WMM |
| MKLN1 | RMND5B | 0.011 | 0.141 | bioplex_WMM boldt boldt_WMM |
| HTRA2 | RMND5B | 0.011 | 0.14 | bioplex_WMM boldt boldt_WMM |
| GID4 | RMND5B | 0.011 | 0.146 | bioplex_WMM boldt boldt_WMM |
| RANBP10 | RMND5B | 0.01 | 0.126 | bioplex_WMM boldt boldt_WMM |
| HTRA2 | ZMYND19 | 0.01 | 0.12 | bioplex_WMM boldt boldt_WMM |
| RMND5A | RMND5B | 0.01 | 0.12 | bioplex_WMM boldt boldt_WMM |
| GID8 | RMND5B | 0.009 | 0.112 | bioplex_WMM boldt boldt_WMM |
| HTRA2 | RANBP9 | 0.008 | 0.049 | bioplex_WMM boldt youn_WMM boldt_WMM |
| YPEL5 | TDGF1 | 0.008 | 0.009 | bioplex (TDGF1) bioplex_WMM |
| GID4 | TDGF1 | 0.007 | 0.007 | bioplex (TDGF1) bioplex_WMM |
| HTRA2 | YPEL5 | 0.007 | 0.007 | bioplex_WMM boldt boldt_WMM |
| MKLN1 | TDGF1 | 0.006 | 0.0 | bioplex (TDGF1) bioplex_WMM |
| RANBP9 | TDGF1 | 0.006 | 0.004 | bioplex (TDGF1) bioplex_WMM |
| HTRA2 | GID8 | 0.006 | 0.006 | bioplex_WMM boldt youn_WMM boldt_WMM |
| ZMYND19 | TDGF1 | 0.006 | 0.004 | bioplex (TDGF1) bioplex_WMM |
| RANBP10 | TDGF1 | 0.003 | 0.011 | bioplex (TDGF1) bioplex_WMM |
| HTRA2 | TDGF1 | 0.0 | 0.001 | bioplex (TDGF1) bioplex_WMM |
Images
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Complex HuMAP2_06026 has an average edge precision of 0.472 which is ranked 2678 out of all 6965 complexes.
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