hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06030
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TAF1 | Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (EC 2.7.11.1) (Cell cycle gene 1 protein) (TBP-associated factor 250 kDa) (p250) (Transcription initiation factor TFIID 250 kDa subunit) (TAF(II)250) (TAFII-250) (TAFII250) | UniProt NCBI |
| TAF13 | Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18) | UniProt NCBI |
| TAF11 | Transcription initiation factor TFIID subunit 11 (TFIID subunit p30-beta) (Transcription initiation factor TFIID 28 kDa subunit) (TAF(II)28) (TAFII-28) (TAFII28) | UniProt NCBI |
| TAF7L | Transcription initiation factor TFIID subunit 7-like (Cancer/testis antigen 40) (CT40) (RNA polymerase II TBP-associated factor subunit Q) (TATA box-binding protein-associated factor 50 kDa) (Transcription initiation factor TFIID 50 kDa subunit) | UniProt NCBI |
| TAF3 | Transcription initiation factor TFIID subunit 3 (140 kDa TATA box-binding protein-associated factor) (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (TAF(II)140) (TAF140) (TAFII-140) (TAFII140) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03022 | 6.63677232536e-12 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Basal transcription factors |
| REAC:R-HSA-73776 | 3.76225081583e-11 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II Promoter Escape |
| REAC:R-HSA-75953 | 3.76225081583e-11 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II Transcription Initiation |
| REAC:R-HSA-76042 | 3.76225081583e-11 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II Transcription Initiation And Promoter Clearance |
| REAC:R-HSA-73779 | 3.76225081583e-11 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| REAC:R-HSA-167162 | 3.76225081583e-11 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II HIV Promoter Escape |
| REAC:R-HSA-167161 | 3.76225081583e-11 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | HIV Transcription Initiation |
| CORUM:492 | 2.4762098927e-10 | 0.8 | TAF1 TAF3 TAF13 TAF11 | DA complex |
| REAC:R-HSA-167172 | 3.19335796647e-10 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Transcription of the HIV genome |
| CORUM:493 | 3.30143569849e-10 | 0.8 | TAF1 TAF3 TAF13 TAF11 | DAB complex |
| REAC:R-HSA-674695 | 6.69220077371e-10 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II Pre-transcription Events |
| REAC:R-HSA-6804756 | 1.14060229938e-09 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Regulation of TP53 Activity through Phosphorylation |
| GO:0005669 | 2.27945309589e-09 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | transcription factor TFIID complex |
| REAC:R-HSA-162599 | 7.88294216037e-09 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Late Phase of HIV Life Cycle |
| REAC:R-HSA-162587 | 1.2652202713e-08 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | HIV Life Cycle |
| REAC:R-HSA-5633007 | 1.82821181031e-08 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Regulation of TP53 Activity |
| REAC:R-HSA-162906 | 1.07739589482e-07 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | HIV Infection |
| GO:0016591 | 1.14617719967e-07 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA polymerase II, holoenzyme |
| CORUM:484 | 2.22812373687e-07 | 0.6 | TAF1 TAF13 TAF11 | TFIID complex |
| CORUM:463 | 2.22812373687e-07 | 0.6 | TAF1 TAF13 TAF11 | TFIID complex |
| CORUM:469 | 2.97053227881e-07 | 0.6 | TAF1 TAF13 TAF11 | TFIID-beta complex |
| CORUM:485 | 2.97053227881e-07 | 0.6 | TAF1 TAF13 TAF11 | TFIID complex, B-cell specific |
| CORUM:509 | 2.97053227881e-07 | 0.6 | TAF1 TAF13 TAF11 | TFIID complex |
| CORUM:514 | 2.97053227881e-07 | 0.6 | TAF1 TAF13 TAF11 | TFIID-beta complex |
| GO:0055029 | 5.00723926593e-07 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | nuclear DNA-directed RNA polymerase complex |
| GO:0000428 | 5.27937183473e-07 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | DNA-directed RNA polymerase complex |
| GO:0030880 | 6.16749937273e-07 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA polymerase complex |
| REAC:R-HSA-3700989 | 1.01349302639e-06 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Transcriptional Regulation by TP53 |
| REAC:R-HSA-5663205 | 1.16866830373e-06 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Infectious disease |
| GO:0090575 | 4.22583570616e-06 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA polymerase II transcription factor complex |
| GO:0006367 | 9.13428048519e-06 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | transcription initiation from RNA polymerase II promoter |
| GO:0044798 | 1.05770080233e-05 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | nuclear transcription factor complex |
| GO:0006352 | 2.5942147504e-05 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | DNA-templated transcription, initiation |
| GO:0061695 | 3.59850228871e-05 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | transferase complex, transferring phosphorus-containing groups |
| CORUM:1318 | 6.7059790554e-05 | 0.4 | TAF1 TAF11 | Transcription initiation factor complex (TAF1, TAF5, TAF11, TAF12, TBP) |
| GO:0005667 | 6.80047135479e-05 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | transcription factor complex |
| REAC:R-HSA-1643685 | 0.000155670343335 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Disease |
| REAC:R-HSA-212436 | 0.000239251603487 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Generic Transcription Pathway |
| CORUM:3009 | 0.000241285563976 | 0.4 | TAF1 TAF11 | TFIID complex |
| CORUM:155 | 0.000241285563976 | 0.4 | TAF1 TAF11 | TFIID complex |
| CORUM:508 | 0.000301566439547 | 0.4 | TAF1 TAF11 | TFIID complex |
| REAC:R-HSA-73857 | 0.000412889072144 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | RNA Polymerase II Transcription |
| REAC:R-HSA-74160 | 0.000713316403356 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | Gene expression (Transcription) |
| GO:0051123 | 0.00139593056214 | 0.6 | TAF7L TAF11 TAF1 | RNA polymerase II preinitiation complex assembly |
| GO:0070897 | 0.00296772889435 | 0.6 | TAF7L TAF11 TAF1 | transcription preinitiation complex assembly |
| GO:1901796 | 0.00326130002182 | 0.8 | TAF1 TAF3 TAF13 TAF11 | regulation of signal transduction by p53 class mediator |
| GO:1990234 | 0.0112296002627 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | transferase complex |
| GO:0072331 | 0.0139267717582 | 0.8 | TAF1 TAF3 TAF13 TAF11 | signal transduction by p53 class mediator |
| REAC:R-HSA-6807505 | 0.0361060371214 | 0.4 | TAF13 TAF11 | RNA polymerase II transcribes snRNA genes |
| GO:0044451 | 0.0442638282809 | 1.0 | TAF7L TAF1 TAF3 TAF13 TAF11 | nucleoplasm part |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TAF7L | TAF1 | 0.991 | 0.909 | bioplex (TAF7L) bioplex_WMM |
| TAF3 | TAF1 | 0.991 | 0.909 | bioplex_WMM youn_WMM Malo fraction |
| TAF3 | TAF7L | 0.816 | 0.773 | bioplex (TAF7L) bioplex_WMM |
| TAF7L | TAF11 | 0.742 | 0.739 | bioplex (TAF7L) bioplex_WMM |
| TAF7L | TAF13 | 0.628 | 0.68 | bioplex (TAF7L) bioplex_WMM |
| TAF1 | TAF13 | 0.011 | 0.141 | bioplex_WMM WMM_only |
| TAF3 | TAF11 | 0.011 | 0.141 | bioplex_WMM WMM_only |
| TAF3 | TAF13 | 0.011 | 0.141 | bioplex_WMM WMM_only |
| TAF13 | TAF11 | 0.011 | 0.141 | bioplex_WMM WMM_only |
| TAF1 | TAF11 | 0.01 | 0.14 | hein_WMM bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06030 has an average edge precision of 0.471 which is ranked 2685 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TAF1 | HuMAP2_03155 HuMAP2_05057 HuMAP2_06030 |
| TAF13 | HuMAP2_05057 HuMAP2_06030 |
| TAF11 | HuMAP2_05057 HuMAP2_06030 |
| TAF7L | HuMAP2_03155 HuMAP2_05057 HuMAP2_06030 |
| TAF3 | HuMAP2_03155 HuMAP2_05057 HuMAP2_06030 |