hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06040
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RABEP1 | Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17) | UniProt NCBI |
| RABGEF1 | Rab5 GDP/GTP exchange factor (RAP1) (Rabaptin-5-associated exchange factor for Rab5) (Rabex-5) | UniProt NCBI |
| HGFAC | Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:50 | 1.00675659188e-05 | 0.666666666667 | RABGEF1 RABEP1 | RAB5-RABAPTIN5-RABEX5 complex |
| REAC:R-HSA-8854214 | 0.00603484671946 | 0.666666666667 | RABGEF1 RABEP1 | TBC/RABGAPs |
| MIRNA:hsa-miR-6739-3p | 0.0243005432667 | 0.666666666667 | RABGEF1 HGFAC | hsa-miR-6739-3p |
| MIRNA:hsa-miR-7156-5p | 0.0243005432667 | 0.666666666667 | RABGEF1 HGFAC | hsa-miR-7156-5p |
| MIRNA:hsa-miR-4273 | 0.0250037840329 | 0.666666666667 | RABGEF1 HGFAC | hsa-miR-4273 |
| MIRNA:hsa-miR-4677-5p | 0.0302063424264 | 0.666666666667 | RABGEF1 HGFAC | hsa-miR-4677-5p |
| MIRNA:hsa-miR-3611 | 0.0393704925026 | 0.666666666667 | RABGEF1 HGFAC | hsa-miR-3611 |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | RABGEF1 RABEP1 | Rab regulation of trafficking |
| CORUM:1090 | 0.0499776345577 | 0.333333333333 | RABEP1 | APLG1-Rababtin5 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RABEP1 | RABGEF1 | 1.0 | 0.949 | hein_WMM bioplex (RABGEF1) bioplex_WMM boldt youn_WMM hein (RABEP1) boldt_WMM |
| RABGEF1 | HGFAC | 0.045 | 0.279 | bioplex (RABGEF1) bioplex_WMM |
| RABEP1 | HGFAC | 0.008 | 0.024 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06040 has an average edge precision of 0.417 which is ranked 3130 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RABEP1 | HuMAP2_02900 HuMAP2_03255 HuMAP2_05932 HuMAP2_06040 |
| RABGEF1 | HuMAP2_03255 HuMAP2_06040 |
| HGFAC | HuMAP2_06040 |