hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06043
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TMED1 | Transmembrane emp24 domain-containing protein 1 (Interleukin-1 receptor-like 1 ligand) (Putative T1/ST2 receptor-binding protein) (p24 family protein gamma-1) (Tp24) (p24gamma1) | UniProt NCBI |
| TMED5 | Transmembrane emp24 domain-containing protein 5 (p24 family protein gamma-2) (p24gamma2) (p28) | UniProt NCBI |
| TMED10 | Transmembrane emp24 domain-containing protein 10 (21 kDa transmembrane-trafficking protein) (S31III125) (S31I125) (Tmp-21-I) (Transmembrane protein Tmp21) (p23) (p24 family protein delta-1) (p24delta1) (p24delta) | UniProt NCBI |
| TMED4 | Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (GMP25iso) (Putative NF-kappa-B-activating protein 156) (p24 family protein alpha-3) (p24alpha3) | UniProt NCBI |
| TMED7 | Transmembrane emp24 domain-containing protein 7 (p24 family protein gamma-3) (p24gamma3) (p27) | UniProt NCBI |
| LIPG | Endothelial lipase (EC 3.1.1.3) (Endothelial cell-derived lipase) (EDL) (EL) | UniProt NCBI |
| TMED9 | Transmembrane emp24 domain-containing protein 9 (GMP25) (Glycoprotein 25L2) (p24 family protein alpha-2) (p24alpha2) (p25) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030134 | 3.91857948075e-09 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | COPII-coated ER to Golgi transport vesicle |
| GO:0005793 | 9.35095673699e-09 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | endoplasmic reticulum-Golgi intermediate compartment |
| GO:0007030 | 7.56545265843e-08 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | Golgi organization |
| GO:0005798 | 1.8023911526e-07 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | Golgi-associated vesicle |
| GO:0006888 | 1.09833709241e-06 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO:0030135 | 2.45902527963e-06 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | coated vesicle |
| GO:0048193 | 3.95741215929e-05 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | Golgi vesicle transport |
| GO:0010256 | 4.10371587902e-05 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | endomembrane system organization |
| GO:0005794 | 0.000453965088566 | 1.0 | TMED1 TMED7 LIPG TMED9 TMED5 TMED10 TMED4 | Golgi apparatus |
| REAC:R-HSA-6811434 | 0.00149069932759 | 0.428571428571 | TMED9 TMED10 TMED7 | COPI-dependent Golgi-to-ER retrograde traffic |
| REAC:R-HSA-6807878 | 0.00153796376749 | 0.428571428571 | TMED9 TMED10 TMED7 | COPI-mediated anterograde transport |
| REAC:R-HSA-8856688 | 0.00370699600406 | 0.428571428571 | TMED9 TMED10 TMED7 | Golgi-to-ER retrograde transport |
| REAC:R-HSA-199977 | 0.00503540377545 | 0.428571428571 | TMED9 TMED10 TMED7 | ER to Golgi Anterograde Transport |
| GO:0031410 | 0.00667947733575 | 1.0 | TMED1 TMED7 LIPG TMED9 TMED5 TMED10 TMED4 | cytoplasmic vesicle |
| GO:0097708 | 0.00670966219137 | 1.0 | TMED1 TMED7 LIPG TMED9 TMED5 TMED10 TMED4 | intracellular vesicle |
| REAC:R-HSA-948021 | 0.00812379143266 | 0.428571428571 | TMED9 TMED10 TMED7 | Transport to the Golgi and subsequent modification |
| REAC:R-HSA-6811442 | 0.0128273022096 | 0.428571428571 | TMED9 TMED10 TMED7 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0006886 | 0.0180209467821 | 0.857142857143 | TMED1 TMED7 TMED10 TMED5 TMED9 TMED4 | intracellular protein transport |
| GO:0071702 | 0.0180623174395 | 1.0 | TMED1 TMED7 LIPG TMED9 TMED5 TMED10 TMED4 | organic substance transport |
| GO:0033116 | 0.0245293846287 | 0.428571428571 | TMED9 TMED10 TMED7 | endoplasmic reticulum-Golgi intermediate compartment membrane |
| REAC:R-HSA-446203 | 0.0383313102015 | 0.428571428571 | TMED9 TMED10 TMED7 | Asparagine N-linked glycosylation |
| MIRNA:hsa-miR-30a-5p | 0.0429788789383 | 0.571428571429 | TMED1 TMED10 TMED5 TMED7 | hsa-miR-30a-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TMED10 | TMED9 | 1.0 | 0.949 | hein_WMM bioplex (TMED10) bioplex_WMM Guru boldt hein (TMED10) gupta_WMM fraction boldt_WMM treiber_WMM |
| TMED10 | TMED4 | 1.0 | 0.949 | hein_WMM bioplex (TMED10) bioplex_WMM Guru boldt hein (TMED10) fraction boldt_WMM treiber_WMM |
| TMED10 | TMED1 | 0.999 | 0.945 | hein_WMM bioplex (TMED10) bioplex_WMM boldt hein (TMED10) boldt_WMM |
| TMED10 | TMED5 | 0.984 | 0.899 | hein_WMM bioplex (TMED10) bioplex_WMM boldt hein (TMED10) gupta_WMM boldt_WMM |
| LIPG | TMED5 | 0.098 | 0.358 | bioplex (LIPG) bioplex_WMM |
| TMED10 | TMED7 | 0.056 | 0.312 | bioplex (TMED10) bioplex_WMM |
| LIPG | TMED9 | 0.051 | 0.296 | bioplex (LIPG) bioplex_WMM |
| TMED4 | LIPG | 0.029 | 0.232 | bioplex (LIPG) bioplex_WMM |
| TMED4 | TMED9 | 0.024 | 0.214 | hein_WMM bioplex_WMM boldt boldt_WMM treiber_WMM |
| TMED1 | TMED4 | 0.023 | 0.205 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED1 | TMED5 | 0.021 | 0.193 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED5 | TMED9 | 0.018 | 0.178 | hein_WMM bioplex_WMM boldt gupta_WMM boldt_WMM |
| TMED1 | TMED9 | 0.016 | 0.158 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED4 | TMED5 | 0.016 | 0.154 | hein_WMM bioplex_WMM boldt boldt_WMM |
| TMED10 | LIPG | 0.015 | 0.139 | bioplex (LIPG) bioplex_WMM |
| TMED4 | TMED7 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| TMED7 | TMED9 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TMED7 | TMED5 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TMED1 | LIPG | 0.006 | 0.007 | bioplex (LIPG) bioplex_WMM |
| TMED1 | TMED7 | 0.006 | 0.007 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06043 has an average edge precision of 0.31 which is ranked 4449 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TMED1 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED5 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED10 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED4 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |
| TMED7 | HuMAP2_00162 HuMAP2_06043 |
| LIPG | HuMAP2_00162 HuMAP2_06043 HuMAP2_06507 |
| TMED9 | HuMAP2_00162 HuMAP2_02885 HuMAP2_06043 |