hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06085
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BCAR3 | Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B) | UniProt NCBI |
| BCAR1 | Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas) | UniProt NCBI |
| NEDD9 | Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55] | UniProt NCBI |
| RHEB | GTP-binding protein Rheb (Ras homolog enriched in brain) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP366 | 0.012672821387 | 0.5 | NEDD9 BCAR1 | TGF-beta Signaling Pathway |
| KEGG:05163 | 0.0399515654372 | 0.5 | RHEB BCAR1 | Human cytomegalovirus infection |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BCAR3 | BCAR1 | 1.0 | 0.949 | bioplex (BCAR3) bioplex_WMM youn_WMM |
| BCAR3 | NEDD9 | 0.442 | 0.586 | bioplex (BCAR3) bioplex_WMM youn_WMM |
| NEDD9 | RHEB | 0.026 | 0.216 | bioplex (NEDD9) bioplex_WMM |
| NEDD9 | BCAR1 | 0.009 | 0.097 | bioplex_WMM youn_WMM WMM_only |
| BCAR1 | RHEB | 0.007 | 0.001 | youn_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_06085 has an average edge precision of 0.37 which is ranked 3642 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BCAR3 | HuMAP2_01043 HuMAP2_01259 HuMAP2_05998 HuMAP2_06085 |
| BCAR1 | HuMAP2_01043 HuMAP2_01259 HuMAP2_05998 HuMAP2_06085 |
| NEDD9 | HuMAP2_01043 HuMAP2_02488 HuMAP2_05998 HuMAP2_06085 |
| RHEB | HuMAP2_02488 HuMAP2_05514 HuMAP2_06085 |