hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06105
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SRSF1 | Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit) | UniProt NCBI |
| SRSF8 | Serine/arginine-rich splicing factor 8 (Pre-mRNA-splicing factor SRP46) (Splicing factor SRp46) (Splicing factor, arginine/serine-rich 2B) | UniProt NCBI |
| CLK3 | Dual specificity protein kinase CLK3 (EC 2.7.12.1) (CDC-like kinase 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03040 | 0.00373360278335 | 0.666666666667 | SRSF1 SRSF8 | Spliceosome |
| WP:WP411 | 0.00739285752446 | 0.666666666667 | SRSF1 CLK3 | mRNA Processing |
| GO:0043484 | 0.0255054888903 | 1.0 | SRSF1 CLK3 SRSF8 | regulation of RNA splicing |
| KEGG:05168 | 0.0315376705583 | 0.666666666667 | SRSF1 SRSF8 | Herpes simplex virus 1 infection |
| CORUM:6261 | 0.0499776345577 | 0.333333333333 | SRSF1 | Histone-2-Histone-4-ASF1-MCM2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CLK3 | SRSF1 | 0.816 | 0.773 | hein_WMM bioplex (CLK3) bioplex_WMM youn_WMM hein (SRSF1) |
| SRSF1 | SRSF8 | 0.651 | 0.69 | hein_WMM bioplex_WMM youn_WMM hein (SRSF1) gupta_WMM |
| CLK3 | SRSF8 | 0.119 | 0.392 | hein_WMM bioplex (CLK3) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_06105 has an average edge precision of 0.618 which is ranked 1845 out of all 6965 complexes.
Related Complexes