hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06115
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KDM4A | Lysine-specific demethylase 4A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) | UniProt NCBI |
| CCL22 | C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)] | UniProt NCBI |
| KDM4B | Lysine-specific demethylase 4B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) | UniProt NCBI |
| ANGEL1 | Protein angel homolog 1 | UniProt NCBI |
| ZNF414 | Zinc finger protein 414 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3214842 | 0.0157733411945 | 0.4 | KDM4A KDM4B | HDMs demethylate histones |
| REAC:R-HSA-5693565 | 0.0380875604325 | 0.4 | KDM4A KDM4B | Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks |
| REAC:R-HSA-5693606 | 0.0390979640759 | 0.4 | KDM4A KDM4B | DNA Double Strand Break Response |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZNF414 | KDM4B | 1.0 | 0.949 | bioplex (ZNF414) bioplex_WMM |
| KDM4A | CCL22 | 0.397 | 0.558 | bioplex (CCL22) bioplex_WMM |
| KDM4A | KDM4B | 0.34 | 0.528 | bioplex (KDM4B) bioplex_WMM |
| ZNF414 | KDM4A | 0.218 | 0.465 | bioplex (ZNF414) bioplex_WMM |
| ZNF414 | ANGEL1 | 0.025 | 0.217 | bioplex (ZNF414) bioplex_WMM |
| ANGEL1 | KDM4B | 0.008 | 0.044 | bioplex_WMM WMM_only |
| ANGEL1 | KDM4A | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
Click to enlarge
Complex HuMAP2_06115 has an average edge precision of 0.395 which is ranked 3378 out of all 6965 complexes.
Related Complexes