hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06116
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP5F1C | ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit) | UniProt NCBI |
| SLC25A4 | ADP/ATP translocase 1 (ADP,ATP carrier protein 1) (ADP,ATP carrier protein, heart/skeletal muscle isoform T1) (Adenine nucleotide translocator 1) (ANT 1) (Solute carrier family 25 member 4) | UniProt NCBI |
| UQCRC2 | Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP111 | 8.35827186966e-06 | 1.0 | UQCRC2 ATP5F1C SLC25A4 | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:05012 | 9.78855844223e-06 | 1.0 | UQCRC2 ATP5F1C SLC25A4 | Parkinson disease |
| KEGG:05016 | 2.6860646392e-05 | 1.0 | UQCRC2 ATP5F1C SLC25A4 | Huntington disease |
| KEGG:00190 | 0.00307537091529 | 0.666666666667 | ATP5F1C UQCRC2 | Oxidative phosphorylation |
| KEGG:05010 | 0.00524007678336 | 0.666666666667 | ATP5F1C UQCRC2 | Alzheimer disease |
| KEGG:04714 | 0.00964399884594 | 0.666666666667 | ATP5F1C UQCRC2 | Thermogenesis |
| REAC:R-HSA-163200 | 0.0444303896492 | 0.666666666667 | ATP5F1C UQCRC2 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UQCRC2 | SLC25A4 | 0.934 | 0.849 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| ATP5F1C | UQCRC2 | 0.914 | 0.839 | bioplex_WMM Guru boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| ATP5F1C | SLC25A4 | 0.549 | 0.643 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM |
Images
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Complex HuMAP2_06116 has an average edge precision of 0.777 which is ranked 1012 out of all 6965 complexes.
Related Complexes