hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06129
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLC30A9 | Zinc transporter 9 (ZnT-9) (Human embryonic lung protein) (HuEL) (Solute carrier family 30 member 9) | UniProt NCBI |
| SRPRA | Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha) | UniProt NCBI |
| COX4I1 | Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Cytochrome c oxidase polypeptide IV) (Cytochrome c oxidase subunit IV isoform 1) (COX IV-1) | UniProt NCBI |
| COX5A | Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6442 | 0.000457035673196 | 0.5 | COX4I1 COX5A | Cytochrome c oxidase, mitochondrial |
| KEGG:04260 | 0.00567266508452 | 0.5 | COX4I1 COX5A | Cardiac muscle contraction |
| WP:WP111 | 0.0071289861505 | 0.5 | COX4I1 COX5A | Electron Transport Chain (OXPHOS system in mitochondria) |
| KEGG:00190 | 0.0136880283161 | 0.5 | COX4I1 COX5A | Oxidative phosphorylation |
| WP:WP4396 | 0.0154631487697 | 0.5 | COX4I1 COX5A | Nonalcoholic fatty liver disease |
| KEGG:05012 | 0.0156041830743 | 0.5 | COX4I1 COX5A | Parkinson disease |
| KEGG:04932 | 0.0173825101547 | 0.5 | COX4I1 COX5A | Non-alcoholic fatty liver disease (NAFLD) |
| KEGG:05010 | 0.0232850911193 | 0.5 | COX4I1 COX5A | Alzheimer disease |
| KEGG:05016 | 0.03037774612 | 0.5 | COX4I1 COX5A | Huntington disease |
| REAC:R-HSA-5628897 | 0.0315540312145 | 0.5 | COX4I1 COX5A | TP53 Regulates Metabolic Genes |
| KEGG:04714 | 0.0427485725169 | 0.5 | COX4I1 COX5A | Thermogenesis |
| REAC:R-HSA-611105 | 0.0435915557177 | 0.5 | COX4I1 COX5A | Respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| COX5A | SLC30A9 | 0.05 | 0.296 | bioplex (COX5A) bioplex_WMM boldt youn_WMM boldt_WMM |
| COX4I1 | COX5A | 0.048 | 0.294 | hein_WMM bioplex (COX4I1,COX5A) bioplex_WMM Guru boldt youn_WMM gupta_WMM fraction boldt_WMM |
| SRPRA | COX5A | 0.041 | 0.269 | bioplex (SRPRA) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| COX4I1 | SLC30A9 | 0.006 | 0.009 | bioplex_WMM boldt youn_WMM boldt_WMM |
| COX4I1 | SRPRA | 0.006 | 0.01 | bioplex (SRPRA) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SRPRA | SLC30A9 | 0.005 | 0.008 | bioplex_WMM boldt youn_WMM boldt_WMM |
Images
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Complex HuMAP2_06129 has an average edge precision of 0.148 which is ranked 6716 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLC30A9 | HuMAP2_02248 HuMAP2_06129 |
| SRPRA | HuMAP2_01699 HuMAP2_02248 HuMAP2_02446 HuMAP2_05917 HuMAP2_06129 |
| COX4I1 | HuMAP2_00163 HuMAP2_02248 HuMAP2_06129 |
| COX5A | HuMAP2_01699 HuMAP2_02248 HuMAP2_06129 |