hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06135
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KDM3A | Lysine-specific demethylase 3A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) | UniProt NCBI |
| POGK | Pogo transposable element with KRAB domain | UniProt NCBI |
| UHRF1 | E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1) | UniProt NCBI |
| STAT3 | Signal transducer and activator of transcription 3 (Acute-phase response factor) | UniProt NCBI |
| PYGO2 | Pygopus homolog 2 | UniProt NCBI |
| TCEAL1 | Transcription elongation factor A protein-like 1 (TCEA-like protein 1) (Nuclear phosphoprotein p21/SIIR) (Transcription elongation factor S-II protein-like 1) | UniProt NCBI |
| GPSM2 | G-protein-signaling modulator 2 (Mosaic protein LGN) | UniProt NCBI |
| PTBP3 | Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1) | UniProt NCBI |
| PHF7 | PHD finger protein 7 (Testis development protein NYD-SP6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1522 | 0.0249698419797 | 0.111111111111 | STAT3 | STAT3 homodimer complex |
| CORUM:7316 | 0.0499262710315 | 0.111111111111 | STAT3 | NFKB1-STAT3 complex |
| CORUM:7317 | 0.0499262710315 | 0.111111111111 | STAT3 | RELA-STAT3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KDM3A | TCEAL1 | 0.962 | 0.869 | bioplex (TCEAL1) bioplex_WMM youn_WMM |
| TCEAL1 | GPSM2 | 0.333 | 0.524 | bioplex (TCEAL1) bioplex_WMM |
| TCEAL1 | UHRF1 | 0.292 | 0.494 | bioplex (TCEAL1) bioplex_WMM |
| TCEAL1 | POGK | 0.263 | 0.482 | bioplex (TCEAL1) bioplex_WMM |
| PHF7 | TCEAL1 | 0.125 | 0.399 | bioplex (PHF7) bioplex_WMM |
| TCEAL1 | PTBP3 | 0.072 | 0.353 | bioplex (TCEAL1) bioplex_WMM |
| TCEAL1 | STAT3 | 0.047 | 0.292 | bioplex (TCEAL1) bioplex_WMM youn_WMM |
| PYGO2 | PTBP3 | 0.022 | 0.195 | fraction |
| GPSM2 | PTBP3 | 0.01 | 0.105 | bioplex_WMM WMM_only |
| KDM3A | PTBP3 | 0.009 | 0.107 | bioplex_WMM youn_WMM WMM_only |
| KDM3A | GPSM2 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| POGK | UHRF1 | 0.009 | 0.092 | bioplex_WMM WMM_only |
| POGK | PTBP3 | 0.009 | 0.094 | bioplex_WMM youn_WMM WMM_only |
| POGK | GPSM2 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| STAT3 | PTBP3 | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only treiber_WMM |
| UHRF1 | PTBP3 | 0.008 | 0.084 | bioplex_WMM youn_WMM WMM_only |
| KDM3A | POGK | 0.008 | 0.084 | bioplex_WMM WMM_only |
| GPSM2 | UHRF1 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| STAT3 | GPSM2 | 0.008 | 0.068 | bioplex_WMM WMM_only |
| KDM3A | UHRF1 | 0.008 | 0.06 | bioplex_WMM youn_WMM WMM_only |
| KDM3A | STAT3 | 0.008 | 0.035 | bioplex_WMM youn_WMM WMM_only |
| STAT3 | UHRF1 | 0.008 | 0.008 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| STAT3 | POGK | 0.007 | 0.005 | bioplex_WMM youn_WMM WMM_only |
Images
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Complex HuMAP2_06135 has an average edge precision of 0.205 which is ranked 6101 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| KDM3A | HuMAP2_00350 HuMAP2_03087 HuMAP2_05897 HuMAP2_05914 HuMAP2_06135 |
| POGK | HuMAP2_06135 |
| UHRF1 | HuMAP2_06135 |
| STAT3 | HuMAP2_06135 |
| PYGO2 | HuMAP2_06135 HuMAP2_06744 |
| TCEAL1 | HuMAP2_00350 HuMAP2_06135 HuMAP2_06382 |
| GPSM2 | HuMAP2_06135 |
| PTBP3 | HuMAP2_06135 HuMAP2_06744 |
| PHF7 | HuMAP2_00003 HuMAP2_04209 HuMAP2_05925 HuMAP2_06135 |