hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06144
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAB8A | Ras-related protein Rab-8A (Oncogene c-mel) | UniProt NCBI |
| MICALL2 | MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2) | UniProt NCBI |
| RAB8B | Ras-related protein Rab-8B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04530 | 1.49652172755e-05 | 1.0 | RAB8B RAB8A MICALL2 | Tight junction |
| REAC:R-HSA-8854214 | 0.00603484671946 | 0.666666666667 | RAB8B RAB8A | TBC/RABGAPs |
| REAC:R-HSA-8873719 | 0.0126269885924 | 0.666666666667 | RAB8B RAB8A | RAB geranylgeranylation |
| GO:0048210 | 0.0135228859698 | 0.666666666667 | RAB8B RAB8A | Golgi vesicle fusion to target membrane |
| REAC:R-HSA-8876198 | 0.0238137546255 | 0.666666666667 | RAB8B RAB8A | RAB GEFs exchange GTP for GDP on RABs |
| GO:0055037 | 0.0248678516681 | 1.0 | RAB8B RAB8A MICALL2 | recycling endosome |
| REAC:R-HSA-9007101 | 0.0444303896492 | 0.666666666667 | RAB8B RAB8A | Rab regulation of trafficking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB8B | RAB8A | 0.89 | 0.818 | bioplex (RAB8B) bioplex_WMM gupta_WMM |
| RAB8B | MICALL2 | 0.639 | 0.686 | bioplex (RAB8B) bioplex_WMM |
| RAB8A | MICALL2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06144 has an average edge precision of 0.53 which is ranked 2332 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAB8A | HuMAP2_01064 HuMAP2_01661 HuMAP2_06144 HuMAP2_06285 |
| MICALL2 | HuMAP2_01661 HuMAP2_06001 HuMAP2_06144 HuMAP2_06285 |
| RAB8B | HuMAP2_01064 HuMAP2_01661 HuMAP2_06001 HuMAP2_06144 HuMAP2_06285 |