hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06146
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DDX19A | ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A) | UniProt NCBI |
| MIF4GD | MIF4G domain-containing protein (SLBP-interacting protein 1) (hSLIP1) | UniProt NCBI |
| DDX25 | ATP-dependent RNA helicase DDX25 (EC 3.6.4.13) (DEAD box protein 25) (Gonadotropin-regulated testicular RNA helicase) | UniProt NCBI |
| CTIF | CBP80/20-dependent translation initiation factor | UniProt NCBI |
| HOOK1 | Protein Hook homolog 1 (h-hook1) (hHK1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6116 | 0.0499494897235 | 0.2 | HOOK1 | Hook1-Vps16 complex |
| CORUM:6117 | 0.0499494897235 | 0.2 | HOOK1 | Hook1-Vps18 complex |
| CORUM:6118 | 0.0499494897235 | 0.2 | HOOK1 | Hook1-Vps39 complex |
| CORUM:6119 | 0.0499494897235 | 0.2 | HOOK1 | Hook1-Vps41 complex |
| CORUM:7441 | 0.0499494897235 | 0.2 | HOOK1 | HOOK1-SHP2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDX19A | DDX25 | 1.0 | 0.949 | bioplex (DDX19A) bioplex_WMM |
| CTIF | MIF4GD | 1.0 | 0.949 | youn (CTIF) bioplex (MIF4GD) bioplex_WMM youn_WMM |
| CTIF | DDX19A | 1.0 | 0.949 | youn (CTIF) bioplex (DDX19A) bioplex_WMM youn_WMM |
| DDX19A | MIF4GD | 0.823 | 0.774 | bioplex (DDX19A) bioplex_WMM youn_WMM |
| CTIF | HOOK1 | 0.177 | 0.435 | youn (CTIF) youn_WMM |
| CTIF | DDX25 | 0.009 | 0.108 | bioplex_WMM WMM_only |
| DDX25 | MIF4GD | 0.009 | 0.101 | bioplex_WMM WMM_only |
| HOOK1 | MIF4GD | 0.007 | 0.01 | youn_WMM WMM_only |
| HOOK1 | DDX19A | 0.007 | 0.006 | youn_WMM WMM_only |
Images
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Complex HuMAP2_06146 has an average edge precision of 0.476 which is ranked 2659 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DDX19A | HuMAP2_00700 HuMAP2_04216 HuMAP2_04774 HuMAP2_06146 HuMAP2_06175 |
| MIF4GD | HuMAP2_04216 HuMAP2_04774 HuMAP2_06146 HuMAP2_06247 |
| DDX25 | HuMAP2_00700 HuMAP2_04216 HuMAP2_04774 HuMAP2_06146 HuMAP2_06175 |
| CTIF | HuMAP2_00058 HuMAP2_04216 HuMAP2_04774 HuMAP2_06146 HuMAP2_06247 |
| HOOK1 | HuMAP2_00058 HuMAP2_03373 HuMAP2_03893 HuMAP2_05370 HuMAP2_06146 |