hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06148
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| METTL14 | N6-adenosine-methyltransferase non-catalytic subunit (Methyltransferase-like protein 14) (hMETTL14) | UniProt NCBI |
| METTL3 | N6-adenosine-methyltransferase catalytic subunit (EC 2.1.1.348) (Methyltransferase-like protein 3) (hMETTL3) (N6-adenosine-methyltransferase 70 kDa subunit) (MT-A70) | UniProt NCBI |
| RBM15B | Putative RNA-binding protein 15B (One-twenty two protein 3) (HsOTT3) (HuOTT3) (RNA-binding motif protein 15B) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0036396 | 5.08584025729e-06 | 1.0 | RBM15B METTL14 METTL3 | RNA N6-methyladenosine methyltransferase complex |
| GO:0045293 | 5.08584025729e-06 | 1.0 | RBM15B METTL14 METTL3 | mRNA editing complex |
| GO:0001510 | 0.00378386515143 | 1.0 | RBM15B METTL14 METTL3 | RNA methylation |
| GO:0021861 | 0.00811409485621 | 0.666666666667 | METTL14 METTL3 | forebrain radial glial cell differentiation |
| GO:0034708 | 0.0180261250619 | 1.0 | RBM15B METTL14 METTL3 | methyltransferase complex |
| GO:0060019 | 0.020283420769 | 0.666666666667 | METTL14 METTL3 | radial glial cell differentiation |
| GO:0009451 | 0.0302766427817 | 1.0 | RBM15B METTL14 METTL3 | RNA modification |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RBM15B | METTL3 | 0.084 | 0.347 | hein_WMM youn_WMM hein (METTL3) |
| METTL14 | METTL3 | 0.05 | 0.294 | hein_WMM youn_WMM hein (METTL3) Malo fraction |
| RBM15B | METTL14 | 0.007 | 0.008 | hein_WMM WMM_only |
Images
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Complex HuMAP2_06148 has an average edge precision of 0.216 which is ranked 5918 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| METTL14 | HuMAP2_00310 HuMAP2_05045 HuMAP2_06148 |
| METTL3 | HuMAP2_00310 HuMAP2_05045 HuMAP2_06148 |
| RBM15B | HuMAP2_00310 HuMAP2_05045 HuMAP2_06148 |