hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06156
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NSMCE3 | Non-structural maintenance of chromosomes element 3 homolog (Non-SMC element 3 homolog) (Hepatocellular carcinoma-associated protein 4) (MAGE-G1 antigen) (Melanoma-associated antigen G1) (Necdin-like protein 2) | UniProt NCBI |
| NSMCE1 | Non-structural maintenance of chromosomes element 1 homolog (Non-SMC element 1 homolog) (EC 2.3.2.27) | UniProt NCBI |
| NSMCE4A | Non-structural maintenance of chromosomes element 4 homolog A (NS4EA) (Non-SMC element 4 homolog A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0030915 | 3.17865016081e-06 | 1.0 | NSMCE4A NSMCE1 NSMCE3 | Smc5-Smc6 complex |
| GO:0106068 | 3.17865016081e-06 | 1.0 | NSMCE4A NSMCE1 NSMCE3 | SUMO ligase complex |
| REAC:R-HSA-3108214 | 2.56967114485e-05 | 1.0 | NSMCE4A NSMCE1 NSMCE3 | SUMOylation of DNA damage response and repair proteins |
| REAC:R-HSA-3108232 | 0.000336595223393 | 1.0 | NSMCE4A NSMCE1 NSMCE3 | SUMO E3 ligases SUMOylate target proteins |
| REAC:R-HSA-2990846 | 0.000374667089817 | 1.0 | NSMCE4A NSMCE1 NSMCE3 | SUMOylation |
| GO:0000793 | 0.0212638981157 | 1.0 | NSMCE4A NSMCE1 NSMCE3 | condensed chromosome |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NSMCE1 | NSMCE3 | 1.0 | 0.949 | hein_WMM bioplex (NSMCE1) bioplex_WMM Malo fraction |
| NSMCE1 | NSMCE4A | 0.961 | 0.869 | hein_WMM bioplex (NSMCE1,NSMCE4A) bioplex_WMM |
| NSMCE3 | NSMCE4A | 0.88 | 0.814 | hein_WMM bioplex (NSMCE4A) bioplex_WMM |
Images
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Complex HuMAP2_06156 has an average edge precision of 0.877 which is ranked 670 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NSMCE3 | HuMAP2_00383 HuMAP2_00828 HuMAP2_04865 HuMAP2_05208 HuMAP2_06156 |
| NSMCE1 | HuMAP2_00383 HuMAP2_00828 HuMAP2_03675 HuMAP2_04865 HuMAP2_05208 HuMAP2_06156 |
| NSMCE4A | HuMAP2_00383 HuMAP2_00828 HuMAP2_04865 HuMAP2_05208 HuMAP2_06156 |