hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06158
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RBBP6 | E3 ubiquitin-protein ligase RBBP6 (EC 2.3.2.27) (Proliferation potential-related protein) (Protein P2P-R) (RING-type E3 ubiquitin transferase RBBP6) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated cellular protein of testis) | UniProt NCBI |
| FNBP4 | Formin-binding protein 4 (Formin-binding protein 30) | UniProt NCBI |
| TOPORS | E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3) | UniProt NCBI |
| YTHDC1 | YTH domain-containing protein 1 (Splicing factor YT521) (YT521-B) | UniProt NCBI |
| ZC3H18 | Zinc finger CCCH domain-containing protein 18 (Nuclear protein NHN1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016607 | 0.000137615733893 | 1.0 | YTHDC1 TOPORS ZC3H18 RBBP6 FNBP4 | nuclear speck |
| GO:0016604 | 0.00553319297715 | 1.0 | YTHDC1 TOPORS ZC3H18 RBBP6 FNBP4 | nuclear body |
| GO:0044451 | 0.0442638282809 | 1.0 | YTHDC1 TOPORS ZC3H18 RBBP6 FNBP4 | nucleoplasm part |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ZC3H18 | RBBP6 | 0.261 | 0.482 | hein_WMM bioplex (ZC3H18) bioplex_WMM youn_WMM gupta_WMM |
| ZC3H18 | FNBP4 | 0.127 | 0.398 | bioplex (ZC3H18) bioplex_WMM youn_WMM |
| ZC3H18 | YTHDC1 | 0.073 | 0.357 | bioplex (ZC3H18) bioplex_WMM youn_WMM |
| ZC3H18 | TOPORS | 0.057 | 0.322 | bioplex (ZC3H18) bioplex_WMM |
| YTHDC1 | RBBP6 | 0.01 | 0.134 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| RBBP6 | TOPORS | 0.008 | 0.093 | bioplex_WMM WMM_only |
| FNBP4 | RBBP6 | 0.008 | 0.085 | bioplex_WMM youn_WMM WMM_only |
| YTHDC1 | FNBP4 | 0.008 | 0.009 | bioplex_WMM youn_WMM WMM_only |
| FNBP4 | TOPORS | 0.007 | 0.006 | bioplex_WMM WMM_only |
| YTHDC1 | TOPORS | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06158 has an average edge precision of 0.189 which is ranked 6323 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RBBP6 | HuMAP2_01088 HuMAP2_03225 HuMAP2_06158 |
| FNBP4 | HuMAP2_01088 HuMAP2_03225 HuMAP2_04605 HuMAP2_06158 |
| TOPORS | HuMAP2_01088 HuMAP2_03225 HuMAP2_05973 HuMAP2_06158 |
| YTHDC1 | HuMAP2_00913 HuMAP2_02016 HuMAP2_02572 HuMAP2_06158 |
| ZC3H18 | HuMAP2_00359 HuMAP2_01088 HuMAP2_03225 HuMAP2_06158 HuMAP2_06262 HuMAP2_06561 HuMAP2_06895 |