hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_06178
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FBXL3 | F-box/LRR-repeat protein 3 (F-box and leucine-rich repeat protein 3A) (F-box/LRR-repeat protein 3A) | UniProt NCBI |
| CRY2 | Cryptochrome-2 | UniProt NCBI |
| CRY1 | Cryptochrome-1 | UniProt NCBI |
| TEKT4 | Tektin-4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04710 | 9.81974852015e-07 | 0.75 | CRY2 CRY1 FBXL3 | Circadian rhythm |
| CORUM:2773 | 3.01612206104e-05 | 0.5 | CRY2 FBXL3 | Ubiquitin E3 ligase (CRY2, SKP1A, CUL1, FBXL3) |
| CORUM:2772 | 3.01612206104e-05 | 0.5 | FBXL3 CRY1 | Ubiquitin E3 ligase (CRY1, SKP1A, CUL1, FBXL3) |
| REAC:R-HSA-400253 | 5.88039824914e-05 | 0.75 | CRY2 CRY1 FBXL3 | Circadian Clock |
| WP:WP3594 | 0.000155677737629 | 0.75 | CRY2 CRY1 FBXL3 | Circadian rhythm related genes |
| GO:0043153 | 0.000296207880886 | 0.75 | CRY2 CRY1 FBXL3 | entrainment of circadian clock by photoperiod |
| GO:0009648 | 0.000351729129078 | 0.75 | CRY2 CRY1 FBXL3 | photoperiodism |
| GO:0009649 | 0.000482716802139 | 0.75 | CRY2 CRY1 FBXL3 | entrainment of circadian clock |
| WP:WP3298 | 0.00077921353079 | 0.5 | CRY2 CRY1 | Melatonin metabolism and effects |
| WP:WP410 | 0.00144137960059 | 0.5 | CRY2 CRY1 | Exercise-induced Circadian Regulation |
| GO:0009882 | 0.00270494046827 | 0.5 | CRY2 CRY1 | blue light photoreceptor activity |
| GO:0071483 | 0.00270494046827 | 0.5 | CRY2 CRY1 | cellular response to blue light |
| GO:0009785 | 0.00270494046827 | 0.5 | CRY2 CRY1 | blue light signaling pathway |
| GO:0009637 | 0.00270494046827 | 0.5 | CRY2 CRY1 | response to blue light |
| GO:0042752 | 0.0297308662285 | 0.75 | CRY2 CRY1 FBXL3 | regulation of circadian rhythm |
| GO:2000323 | 0.0405595771497 | 0.5 | CRY2 CRY1 | negative regulation of glucocorticoid receptor signaling pathway |
| GO:2000322 | 0.0405595771497 | 0.5 | CRY2 CRY1 | regulation of glucocorticoid receptor signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CRY2 | CRY1 | 0.996 | 0.929 | hein_WMM bioplex (CRY1) bioplex_WMM |
| CRY1 | FBXL3 | 0.149 | 0.411 | bioplex (CRY1,FBXL3) bioplex_WMM |
| CRY2 | TEKT4 | 0.076 | 0.357 | bioplex (TEKT4) bioplex_WMM |
| CRY1 | TEKT4 | 0.074 | 0.356 | bioplex (TEKT4) bioplex_WMM |
| CRY2 | FBXL3 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| FBXL3 | TEKT4 | 0.0 | 0.006 | bioplex (TEKT4) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_06178 has an average edge precision of 0.344 which is ranked 4068 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FBXL3 | HuMAP2_02639 HuMAP2_03436 HuMAP2_06178 |
| CRY2 | HuMAP2_02639 HuMAP2_02822 HuMAP2_06178 HuMAP2_06686 |
| CRY1 | HuMAP2_02639 HuMAP2_02822 HuMAP2_05794 HuMAP2_06178 HuMAP2_06686 |
| TEKT4 | HuMAP2_02639 HuMAP2_06049 HuMAP2_06178 HuMAP2_06217 HuMAP2_06686 |