hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06180
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ZMYM3 | Zinc finger MYM-type protein 3 (Zinc finger protein 261) | UniProt NCBI |
| SLC9A3R1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | UniProt NCBI |
| UBQLN1 | Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1) | UniProt NCBI |
| ZMYM4 | Zinc finger MYM-type protein 4 (Zinc finger protein 262) | UniProt NCBI |
| IRF2BP2 | Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:048020_22 | 0.0306536094775 | 0.6 | IRF2BP2 ZMYM4 ZMYM3 | soft tissue 2; chondrocytes[Approved,Medium] |
| CORUM:687 | 0.0499494897235 | 0.2 | SLC9A3R1 | CFTR-NHERF-beta(2)AR signaling complex |
| CORUM:6702 | 0.0499494897235 | 0.2 | SLC9A3R1 | CXCR2-NHERF1-PLC-beta-3 complex |
| CORUM:6788 | 0.0499494897235 | 0.2 | SLC9A3R1 | SLC9A3R1-ACTN4 complex |
| CORUM:6790 | 0.0499494897235 | 0.2 | SLC9A3R1 | NHERF1-PRKCZ complex |
| CORUM:6791 | 0.0499494897235 | 0.2 | SLC9A3R1 | NHERF1-NPT2A-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UBQLN1 | SLC9A3R1 | 0.511 | 0.63 | bioplex_WMM fraction |
| UBQLN1 | IRF2BP2 | 0.054 | 0.305 | fraction bioplex_WMM |
| UBQLN1 | ZMYM4 | 0.051 | 0.295 | bioplex_WMM Guru fraction |
| UBQLN1 | ZMYM3 | 0.047 | 0.293 | bioplex_WMM Guru fraction |
| ZMYM4 | ZMYM3 | 0.007 | 0.006 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| IRF2BP2 | ZMYM3 | 0.007 | 0.007 | youn_WMM WMM_only |
| IRF2BP2 | ZMYM4 | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only |
| ZMYM4 | SLC9A3R1 | 0.0 | 0.017 | fraction |
| IRF2BP2 | SLC9A3R1 | 0.0 | 0.002 | fraction |
Images
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Complex HuMAP2_06180 has an average edge precision of 0.174 which is ranked 6490 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ZMYM3 | HuMAP2_04021 HuMAP2_04761 HuMAP2_06180 |
| SLC9A3R1 | HuMAP2_05594 HuMAP2_06180 HuMAP2_06548 HuMAP2_06957 |
| UBQLN1 | HuMAP2_00203 HuMAP2_05594 HuMAP2_05984 HuMAP2_06180 HuMAP2_06957 |
| ZMYM4 | HuMAP2_03164 HuMAP2_06180 |
| IRF2BP2 | HuMAP2_01837 HuMAP2_02068 HuMAP2_04016 HuMAP2_04843 HuMAP2_06180 |