hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06188
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NECTIN1 | Nectin-1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin cell adhesion molecule 1) (Poliovirus receptor-related protein 1) (CD antigen CD111) | UniProt NCBI |
| NECTIN3 | Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113) | UniProt NCBI |
| ASB6 | Ankyrin repeat and SOCS box protein 6 (ASB-6) | UniProt NCBI |
| NPTX1 | Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I) | UniProt NCBI |
| MAK | Serine/threonine-protein kinase MAK (EC 2.7.11.1) (Male germ cell-associated kinase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-420597 | 0.000202356855584 | 0.4 | NECTIN1 NECTIN3 | Nectin/Necl trans heterodimerization |
| REAC:R-HSA-418990 | 0.00472180750517 | 0.4 | NECTIN1 NECTIN3 | Adherens junctions interactions |
| KEGG:04520 | 0.00998234880291 | 0.4 | NECTIN1 NECTIN3 | Adherens junction |
| REAC:R-HSA-421270 | 0.0126969553517 | 0.4 | NECTIN1 NECTIN3 | Cell-cell junction organization |
| KEGG:04514 | 0.0213955956609 | 0.4 | NECTIN1 NECTIN3 | Cell adhesion molecules (CAMs) |
| REAC:R-HSA-446728 | 0.0332320424718 | 0.4 | NECTIN1 NECTIN3 | Cell junction organization |
| CORUM:6611 | 0.0499494897235 | 0.2 | NECTIN1 | PDZD11-nectin1 complex |
| CORUM:6612 | 0.0499494897235 | 0.2 | NECTIN3 | PDZD11-nectin3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NECTIN1 | NECTIN3 | 0.974 | 0.886 | bioplex (NECTIN3) bioplex_WMM |
| NECTIN3 | NPTX1 | 0.104 | 0.368 | bioplex (NECTIN3) bioplex_WMM |
| NECTIN3 | MAK | 0.095 | 0.359 | bioplex (NECTIN3) bioplex_WMM |
| MAK | ASB6 | 0.093 | 0.355 | bioplex (ASB6) bioplex_WMM |
| NECTIN1 | MAK | 0.008 | 0.091 | bioplex_WMM WMM_only |
| NECTIN1 | NPTX1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| NPTX1 | MAK | 0.007 | 0.0 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_06188 has an average edge precision of 0.295 which is ranked 4682 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NECTIN1 | HuMAP2_01843 HuMAP2_02751 HuMAP2_06188 |
| NECTIN3 | HuMAP2_01843 HuMAP2_02751 HuMAP2_06188 |
| ASB6 | HuMAP2_03005 HuMAP2_06188 |
| NPTX1 | HuMAP2_02751 HuMAP2_06188 |
| MAK | HuMAP2_02751 HuMAP2_06188 |