hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_06190
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| C1QBP | Complement component 1 Q subcomponent-binding protein, mitochondrial (ASF/SF2-associated protein p32) (Glycoprotein gC1qBP) (C1qBP) (Hyaluronan-binding protein 1) (Mitochondrial matrix protein p32) (gC1q-R protein) (p33) (SF2AP32) | UniProt NCBI |
| LUC7L | Putative RNA-binding protein Luc7-like 1 (Putative SR protein LUC7B1) (SR+89) | UniProt NCBI |
| PRPF38B | Pre-mRNA-splicing factor 38B (Sarcoma antigen NY-SAR-27) | UniProt NCBI |
| SRPK1 | SRSF protein kinase 1 (EC 2.7.11.1) (SFRS protein kinase 1) (Serine/arginine-rich protein-specific kinase 1) (SR-protein-specific kinase 1) | UniProt NCBI |
| SRPK2 | SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0022618 | 0.00719806897192 | 0.8 | SRPK1 C1QBP LUC7L SRPK2 | ribonucleoprotein complex assembly |
| GO:0071826 | 0.00949806952278 | 0.8 | SRPK1 C1QBP LUC7L SRPK2 | ribonucleoprotein complex subunit organization |
| GO:0000245 | 0.0199719657189 | 0.6 | SRPK1 LUC7L SRPK2 | spliceosomal complex assembly |
| WP:WP411 | 0.0254557044772 | 0.4 | SRPK1 SRPK2 | mRNA Processing |
| GO:0000377 | 0.0464577202339 | 0.8 | SRPK1 C1QBP LUC7L SRPK2 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.0464577202339 | 0.8 | SRPK1 C1QBP LUC7L SRPK2 | mRNA splicing, via spliceosome |
| GO:0000375 | 0.0482714880996 | 0.8 | SRPK1 C1QBP LUC7L SRPK2 | RNA splicing, via transesterification reactions |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LUC7L | C1QBP | 0.923 | 0.844 | hein_WMM bioplex (LUC7L) bioplex_WMM hein (C1QBP) fraction |
| SRPK2 | LUC7L | 0.914 | 0.839 | bioplex (LUC7L) bioplex_WMM youn_WMM fraction |
| PRPF38B | LUC7L | 0.881 | 0.816 | bioplex (LUC7L) bioplex_WMM youn_WMM gupta_WMM |
| SRPK1 | LUC7L | 0.774 | 0.751 | bioplex (LUC7L,SRPK1) bioplex_WMM youn_WMM gupta_WMM fraction |
| SRPK1 | SRPK2 | 0.064 | 0.348 | bioplex_WMM boldt youn_WMM boldt_WMM |
| PRPF38B | SRPK1 | 0.007 | 0.009 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PRPF38B | SRPK2 | 0.007 | 0.01 | bioplex_WMM youn_WMM WMM_only |
| SRPK2 | C1QBP | 0.006 | 0.008 | bioplex_WMM boldt boldt_WMM |
| SRPK1 | C1QBP | 0.005 | 0.008 | bioplex_WMM boldt boldt_WMM |
| PRPF38B | C1QBP | 0.0 | 0.008 | bioplex (PRPF38B) bioplex_WMM fraction |
Images
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Complex HuMAP2_06190 has an average edge precision of 0.364 which is ranked 3701 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| C1QBP | HuMAP2_04103 HuMAP2_04211 HuMAP2_04355 HuMAP2_04456 HuMAP2_05755 HuMAP2_06190 |
| LUC7L | HuMAP2_03353 HuMAP2_04355 HuMAP2_06190 |
| PRPF38B | HuMAP2_02300 HuMAP2_03225 HuMAP2_03353 HuMAP2_04355 HuMAP2_06190 |
| SRPK1 | HuMAP2_02899 HuMAP2_03353 HuMAP2_03491 HuMAP2_04347 HuMAP2_06190 |
| SRPK2 | HuMAP2_02899 HuMAP2_03353 HuMAP2_03491 HuMAP2_04347 HuMAP2_06190 |